JP7720914B2 - ヘテロアリール－ケトン縮合アザデカリングルココルチコイド受容体調節因子を調製する方法 - Google Patents

ヘテロアリール－ケトン縮合アザデカリングルココルチコイド受容体調節因子を調製する方法

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JP7720914B2
JP7720914B2 JP2023538962A JP2023538962A JP7720914B2 JP 7720914 B2 JP7720914 B2 JP 7720914B2 JP 2023538962 A JP2023538962 A JP 2023538962A JP 2023538962 A JP2023538962 A JP 2023538962A JP 7720914 B2 JP7720914 B2 JP 7720914B2
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JP2024501956A (ja
JP2024501956A5 (enExample
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マーク ドナー ジェフリー
ジョーン ハント ヘイゼル
レモンズ トラビス
リード ギャリー
ギャレック キリアン
シー．スティーブンズ トーマス
ダイスケ ガマック ヤマガタ アダム
ルー ユンクオ
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コーセプト セラピューティクス， インコーポレイテッド
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4745—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13—Crystalline forms, e.g. polymorphs

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Psychiatry (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
JP2023538962A 2020-12-25 2021-12-22 ヘテロアリール－ケトン縮合アザデカリングルココルチコイド受容体調節因子を調製する方法 Active JP7720914B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CNPCT/CN2020/139524 2020-12-25
PCT/CN2020/139524 WO2022134033A1 (en) 2020-12-25 2020-12-25 Methods of preparing heteroaryl-ketone fused azadecalin glucocorticoid receptor modulators
PCT/US2021/064947 WO2022140600A1 (en) 2020-12-25 2021-12-22 Methods of preparing heteroaryl-ketone fused azadecalin glucocorticoid receptor modulators

Publications (3)

Publication Number Publication Date
JP2024501956A JP2024501956A (ja) 2024-01-17
JP2024501956A5 JP2024501956A5 (enExample) 2024-07-22
JP7720914B2 true JP7720914B2 (ja) 2025-08-08

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JP2023538962A Active JP7720914B2 (ja) 2020-12-25 2021-12-22 ヘテロアリール－ケトン縮合アザデカリングルココルチコイド受容体調節因子を調製する方法

Country Status (10)

Country Link
US (2) US12152028B2 (enExample)
EP (1) EP4267577A4 (enExample)
JP (1) JP7720914B2 (enExample)
KR (1) KR20230124985A (enExample)
CN (1) CN116867780A (enExample)
AU (2) AU2021410756B2 (enExample)
CA (1) CA3202354A1 (enExample)
IL (1) IL304005A (enExample)
MX (1) MX2023007404A (enExample)
WO (2) WO2022134033A1 (enExample)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2022134033A1 (en) 2020-12-25 2022-06-30 Corcept Therapeutics Incorporated Methods of preparing heteroaryl-ketone fused azadecalin glucocorticoid receptor modulators
WO2024077169A1 (en) 2022-10-06 2024-04-11 Corcept Therapeutics Incorporated Formulations of glucocorticoid receptor modulators

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Publication number Publication date
AU2021410756A1 (en) 2023-07-06
EP4267577A4 (en) 2024-11-27
WO2022140600A1 (en) 2022-06-30
JP2024501956A (ja) 2024-01-17
CN116867780A (zh) 2023-10-10
CA3202354A1 (en) 2022-06-30
US12152028B2 (en) 2024-11-26
AU2021410756A9 (en) 2024-09-12
MX2023007404A (es) 2023-08-21
US20220227753A1 (en) 2022-07-21
US20250145620A1 (en) 2025-05-08
KR20230124985A (ko) 2023-08-28
AU2025203341B2 (en) 2026-03-05
EP4267577A1 (en) 2023-11-01
IL304005A (en) 2023-08-01
AU2025203341A1 (en) 2025-05-29
WO2022134033A1 (en) 2022-06-30
AU2021410756B2 (en) 2025-02-13

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