JP7706671B2 - 眼疾患モデル動物 - Google Patents

眼疾患モデル動物 Download PDF

Info

Publication number
JP7706671B2
JP7706671B2 JP2024573667A JP2024573667A JP7706671B2 JP 7706671 B2 JP7706671 B2 JP 7706671B2 JP 2024573667 A JP2024573667 A JP 2024573667A JP 2024573667 A JP2024573667 A JP 2024573667A JP 7706671 B2 JP7706671 B2 JP 7706671B2
Authority
JP
Japan
Prior art keywords
animal
meibomian gland
model animal
cells
eye disease
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
JP2024573667A
Other languages
English (en)
Japanese (ja)
Other versions
JPWO2024257328A5 (https=
JPWO2024257328A1 (https=
Inventor
幸 杉田
佳奈 池本
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Senju Pharmaceutical Co Ltd
Original Assignee
Senju Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Senju Pharmaceutical Co Ltd filed Critical Senju Pharmaceutical Co Ltd
Publication of JPWO2024257328A1 publication Critical patent/JPWO2024257328A1/ja
Publication of JPWO2024257328A5 publication Critical patent/JPWO2024257328A5/ja
Application granted granted Critical
Publication of JP7706671B2 publication Critical patent/JP7706671B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K67/00—Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
    • A01K67/027—New or modified breeds of vertebrates
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/15—Medicinal preparations ; Physical properties thereof, e.g. dissolubility
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Environmental Sciences (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Zoology (AREA)
  • Animal Husbandry (AREA)
  • Biodiversity & Conservation Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
JP2024573667A 2023-06-16 2023-06-16 眼疾患モデル動物 Active JP7706671B2 (ja)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/JP2023/022377 WO2024257328A1 (ja) 2023-06-16 2023-06-16 眼疾患モデル動物

Publications (3)

Publication Number Publication Date
JPWO2024257328A1 JPWO2024257328A1 (https=) 2024-12-19
JPWO2024257328A5 JPWO2024257328A5 (https=) 2025-05-28
JP7706671B2 true JP7706671B2 (ja) 2025-07-11

Family

ID=93851675

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2024573667A Active JP7706671B2 (ja) 2023-06-16 2023-06-16 眼疾患モデル動物

Country Status (2)

Country Link
JP (1) JP7706671B2 (https=)
WO (1) WO2024257328A1 (https=)

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20200054697A1 (en) 2017-04-17 2020-02-20 Baylor College Of Medicine Commensal bacteria as novel treatment for dry eye and sjogren syndrome
JP2021534202A (ja) 2018-08-20 2021-12-09 デューク ユニバーシティ 眼科疾患を処置する為の薬物の為の方法及び組成物
WO2022065436A1 (ja) 2020-09-25 2022-03-31 株式会社イーダーム ドライアイの予防剤，改善剤および治療剤
JP2022542889A (ja) 2019-07-25 2022-10-07 ザ・ユニバーシティ・オブ・マンチェスター ドライアイ疾患のためのｔｓｇ６ポリペプチドフラグメント

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20200054697A1 (en) 2017-04-17 2020-02-20 Baylor College Of Medicine Commensal bacteria as novel treatment for dry eye and sjogren syndrome
JP2021534202A (ja) 2018-08-20 2021-12-09 デューク ユニバーシティ 眼科疾患を処置する為の薬物の為の方法及び組成物
JP2022542889A (ja) 2019-07-25 2022-10-07 ザ・ユニバーシティ・オブ・マンチェスター ドライアイ疾患のためのｔｓｇ６ポリペプチドフラグメント
WO2022065436A1 (ja) 2020-09-25 2022-03-31 株式会社イーダーム ドライアイの予防剤，改善剤および治療剤

Non-Patent Citations (6)

* Cited by examiner, † Cited by third party
Title
American journal of ophthalmology，2023年03月，Vol. 247，p. 42-60，Manuscript
Experimental Eye Research，2022年02月，Vol. 219，pp. 108983 (1-10)
Eyelid blood vessel and meibomian gland changes ina sclerodermatous chronic GVHD mouse model，Ocul. Surf.，2021年10月26日，Vol.26，p.328-341，DOI: 10.1016/j.jtos.2021.10.006，Manuscript
Investigative Opthalmology & Visual Science，2008年，Vol. 49, No. 1，pp. 34-41
あたらしい眼科，2017年，Vol.34, No.4，p.571-574
林良夫ほか，シェーグレン症候群疾患モデルのＳＣＩＤマウスへの移入，炎症，1995年，Vol. 15, No. 3，pp. 225-230

Also Published As

Publication number Publication date
WO2024257328A1 (ja) 2024-12-19
JPWO2024257328A1 (https=) 2024-12-19

Similar Documents

Publication Publication Date Title
Yao et al. Deletion of autophagy inducer RB1CC1 results in degeneration of the retinal pigment epithelium
Mullins et al. Choriocapillaris vascular dropout related to density of drusen in human eyes with early age-related macular degeneration
Pauly et al. New tools for the evaluation of toxic ocular surface changes in the rat
Nakashizuka et al. Clinicopathologic findings in polypoidal choroidal vasculopathy
Al-Saedi et al. Dry eye disease: present challenges in the management and future trends
Wu et al. The role of NLRP3 and IL-1β in refractory epilepsy brain injury
US20170188814A1 (en) Inflammatory eye disorders
US20180338952A1 (en) Compositions and methods for treating and diagnosing ocular disorders
Kumar et al. Vascular associations and dynamic process motility in perivascular myeloid cells of the mouse choroid: implications for function and senescent change
Kheirkhah et al. Subtarsal fibrosis is associated with ocular surface epitheliopathy in graft-versus-host disease
CN101111253A (zh) 眼病治疗剂
Zhang et al. Isotretinoin impairs the secretory function of meibomian gland via the PPARγ signaling pathway
Yiu et al. Long-term evolution and remodeling of soft drusen in rhesus macaques
Furuyoshi et al. Ultrastructural changes in the trabecular meshwork of juvenile glaucoma
Cibis et al. Corneal keloid in Lowe's syndrome
EP3226853B1 (en) Animal model for dry eye and methods of use of such animals
Muz et al. Comparison of BAK-preserved latanoprost and polyquad-preserved travoprost on ocular surface parameters in patients with glaucoma and ocular hypertension
Fan et al. Extensive Sub-RPE complement deposition in a nonhuman primate model of early-stage diabetic retinopathy
Pillunat et al. Scheimpflug corneal densitometry changes after trabeculectomy
JP7706671B2 (ja) 眼疾患モデル動物
Sidman et al. Pigment epithelial and retinal phenotypes in the vitiligo mivit, mutant mouse.
Provost et al. Morphologic and electroretinographic phenotype of SR-BI knockout mice after a long-term atherogenic diet
WO2011097577A2 (en) Compositions and methods for treating or preventing retinal degeneration
WO2008136772A1 (en) Method of monitoring retinopathy
JP2016532658A (ja) 眼病の処置のためのＮ−（４−ｔｅｒｔ−ブチルベンジル）−３−クロロ−Ｎ−［２−（４−クロロ−３−エチル−フェニル）−エチル］−２−フルオロ−５−トリフルオロメチル−ベンズアミドの使用

Legal Events

Date Code Title Description
A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20241213

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20241213

A871 Explanation of circumstances concerning accelerated examination

Free format text: JAPANESE INTERMEDIATE CODE: A871

Effective date: 20241213

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20250318

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20250514

TRDD Decision of grant or rejection written
A01 Written decision to grant a patent or to grant a registration (utility model)

Free format text: JAPANESE INTERMEDIATE CODE: A01

Effective date: 20250603

A61 First payment of annual fees (during grant procedure)

Free format text: JAPANESE INTERMEDIATE CODE: A61

Effective date: 20250701

R150 Certificate of patent or registration of utility model

Ref document number: 7706671

Country of ref document: JP

Free format text: JAPANESE INTERMEDIATE CODE: R150