JP7682859B2 - 前立腺幹細胞抗原（ｐｓｃａ）キメラ抗原受容体（ｃａｒ）を含む組成物および方法 - Google Patents

前立腺幹細胞抗原（ｐｓｃａ）キメラ抗原受容体（ｃａｒ）を含む組成物および方法 Download PDF

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JP7682859B2
JP7682859B2 JP2022515826A JP2022515826A JP7682859B2 JP 7682859 B2 JP7682859 B2 JP 7682859B2 JP 2022515826 A JP2022515826 A JP 2022515826A JP 2022515826 A JP2022515826 A JP 2022515826A JP 7682859 B2 JP7682859 B2 JP 7682859B2
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ヤンビン チャオ
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ザ トラスティーズ オブ ザ ユニバーシティ オブ ペンシルバニア
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    • A61K40/4274—Prostate associated antigens e.g. Prostate stem cell antigen [PSCA]; Prostate carcinoma tumor antigen [PCTA]; Prostatic acid phosphatase [PAP]; Prostate-specific G-protein-coupled receptor [PSGR]
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JP2022515826A 2019-09-11 2020-09-10 前立腺幹細胞抗原（ｐｓｃａ）キメラ抗原受容体（ｃａｒ）を含む組成物および方法 Active JP7682859B2 (ja)

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US201962898896P 2019-09-11 2019-09-11
US62/898,896 2019-09-11
US202062985808P 2020-03-05 2020-03-05
US62/985,808 2020-03-05
PCT/US2020/050090 WO2021050656A1 (en) 2019-09-11 2020-09-10 Compositions and methods comprising prostate stem cell antigen (psca) chimeric antigen receptors (cars)

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BR112022023371A2 (pt) * 2020-05-22 2022-12-20 Chongqing Prec Biotech Co Ltd Proteína de fusão para reversão do microambiente tumoral, vetor de expressão, célula imune, receptor de antígeno quimérico resistente à imunossupressão tumoral, sequência de ácido nucleico, método para preparar uma célula imune, composição farmacêutica, e, uso da composição farmacêutica
EP4479068A4 (en) * 2022-02-18 2026-01-07 Univ California ENHANCED MULTIPLICATION AND FUNCTION OF PRIMARY HUMAN NK CELLS BY A CHIMERICAL CYTOKINE RECEPTOR
WO2024040194A1 (en) 2022-08-17 2024-02-22 Capstan Therapeutics, Inc. Conditioning for in vivo immune cell engineering
KR20250158048A (ko) 2023-03-03 2025-11-05 아스널 바이오사이언시스, 인크. Psma 및 ca9을 표적으로 하는 시스템
WO2025179294A2 (en) 2024-02-22 2025-08-28 Capstan Therapeutics, Inc. Immune engineering amplification
WO2025235801A1 (en) 2024-05-08 2025-11-13 City Of Hope Antibodies targeted to osteopontin and uses thereof for reducing resistance of solid tumors immune cell therapy

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JP2010538080A (ja) 2007-09-04 2010-12-09 ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア 癌のターゲッティングおよび検出のための高親和性抗前立腺幹細胞抗原（ｐｓｃａ）抗体
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JP2016515810A (ja) 2013-03-15 2016-06-02 アントフロゲネシス コーポレーション 修飾されたｔリンパ球
JP2017513818A (ja) 2014-03-15 2017-06-01 ノバルティス アーゲー キメラ抗原受容体を使用する癌の処置
JP2018530333A (ja) 2015-10-06 2018-10-18 シティ・オブ・ホープＣｉｔｙ ｏｆ Ｈｏｐｅ Ｐｓｃａを標的とするキメラ抗原レセプター
US20190055297A1 (en) 2017-04-13 2019-02-21 The Trustees Of The University Of Pennsylvania Use of gene editing to generate universal tcr re-directed t cells for adoptive immunotherapy
US20190247432A1 (en) 2017-12-12 2019-08-15 The Trustees Of The University Of Pennsylvania Genetically Modified Immune Cells Targeting NY-ESO-1 and Methods of Use Thereof
CN109593726A (zh) 2018-12-26 2019-04-09 重庆精准生物技术有限公司 增强car-t细胞归巢到实体肿瘤组织能力的试剂及其应用

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