JP7670705B2 - 4-1bblアジュバント添加した組み換え改変ワクシニアウイルスアンカラ(mva)の医学的使用 - Google Patents

4-1bblアジュバント添加した組み換え改変ワクシニアウイルスアンカラ(mva)の医学的使用 Download PDF

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JP7670705B2
JP7670705B2 JP2022528249A JP2022528249A JP7670705B2 JP 7670705 B2 JP7670705 B2 JP 7670705B2 JP 2022528249 A JP2022528249 A JP 2022528249A JP 2022528249 A JP2022528249 A JP 2022528249A JP 7670705 B2 JP7670705 B2 JP 7670705B2
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ヒンターベルガー・マリア
メディナ・エチェベルス・ホセ
ハビャン・マティアス
ハウスマン・ユルゲン
カッラ・マルクス
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バヴァリアン・ノルディック・アクティーゼルスカブ
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JP2022528249A 2019-11-20 2020-11-20 4-1bblアジュバント添加した組み換え改変ワクシニアウイルスアンカラ(mva)の医学的使用 Active JP7670705B2 (ja)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
EP19210369.5 2019-11-20
EP19210369 2019-11-20
EP20191226.8 2020-08-14
EP20191226 2020-08-14
EP20193706.7 2020-08-31
EP20193706 2020-08-31
PCT/EP2020/082888 WO2021099572A1 (en) 2019-11-20 2020-11-20 Medical uses of 4-1bbl adjuvanted recombinant modified vaccinia virus ankara (mva)

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JP2023503858A JP2023503858A (ja) 2023-02-01
JP2023503858A5 JP2023503858A5 (enExample) 2023-10-26
JP7670705B2 true JP7670705B2 (ja) 2025-04-30

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US (1) US20230059344A1 (enExample)
EP (1) EP4061404A1 (enExample)
JP (1) JP7670705B2 (enExample)
KR (1) KR20220116191A (enExample)
CN (1) CN114929268A (enExample)
AU (1) AU2020388973A1 (enExample)
BR (1) BR112022009797A2 (enExample)
CA (1) CA3159666A1 (enExample)
IL (1) IL293012A (enExample)
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CN111050790B (zh) * 2017-08-24 2024-07-12 巴法里安诺迪克有限公司 通过静脉内施用重组mva和抗体治疗癌症的组合疗法
US12194157B2 (en) 2020-04-09 2025-01-14 Finncure Oy Carrier for targeted delivery to a host
FI20215508A1 (en) 2020-04-09 2021-10-10 Niemelae Erik Johan Mimetic nanoparticles to prevent the spread of new coronaviruses and reduce the rate of infection
CN117004579B (zh) * 2023-06-29 2024-11-15 苏州恩立维生物科技有限公司 重组溶瘤牛痘病毒及其应用

Citations (4)

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WO2014037124A1 (en) 2012-09-04 2014-03-13 Bavarian Nordic A/S Methods and compositions for enhancing vaccine immune responses
JP2019500907A (ja) 2016-01-08 2019-01-17 ジオバックス・インコーポレイテッド 腫瘍関連抗原に対する免疫応答を誘起するための組成物及び方法
WO2019038388A1 (en) 2017-08-24 2019-02-28 Bavarian Nordic A/S POLYTHERAPY FOR THE TREATMENT OF CANCER BY INTRAVENOUS ADMINISTRATION OF RECOMBINANT MVA AND ANTIBODY
WO2020104531A1 (en) 2018-11-20 2020-05-28 Bavarian Nordic A/S Therapy for treating cancer with an intratumoral and/or intravenous administration of a recombinant mva encoding 4-1bbl (cd137l) and/or cd40l

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US6969609B1 (en) * 1998-12-09 2005-11-29 The United States Of America As Represented By The Department Of Health And Human Serivces Recombinant vector expressing multiple costimulatory molecules and uses thereof
UA76731C2 (uk) 2000-11-23 2006-09-15 Баваріан Нордік А/С Штам mva-bn модифікованого вірусу коров'ячої віспи ankara, фармацевтична композиція, вакцина, застосування mva-bn для приготування лікарського препарату та для приготування вакцини, спосіб введення гомологічної і/або гетерологічної послідовності нуклеїнової кислоти в клітини-мішені in vitro, спосіб одержання пептиду або білка, спосіб одержання mva-bn, клітина, набір для основної/бустерної імунізації
EP2345665A3 (en) 2001-12-04 2012-02-15 Bavarian Nordic A/S Flavivirus NS1 subunit vaccine
US8691502B2 (en) * 2008-10-31 2014-04-08 Tremrx, Inc. T-cell vaccination with viral vectors via mechanical epidermal disruption
MX367100B (es) * 2012-02-17 2019-08-05 The Children´S Hospital Of Philadelphia Composiciones del vector aav y metodos para su transferencia genetica a celulas, organos y tejidos.
CA2942501A1 (en) * 2014-03-17 2015-09-24 Tapimmune Inc. Nucleic acid molecule vaccine compositions and uses thereof
KR102499737B1 (ko) * 2014-05-13 2023-02-13 버베리안 노딕 에이/에스 종양 항원을 발현하는 재조합 폭스바이러스 및 면역 체크포인트 분자 길항제 또는 효현제로 암을 치료하기 위한 복합 요법
IL261321B2 (en) * 2016-02-25 2023-12-01 Memorial Sloan Kettering Cancer Center Recombinant mva or mvadele3l expressing human flt3l and use thereof as immuno-therapeutic agents against solid tumors
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WO2014037124A1 (en) 2012-09-04 2014-03-13 Bavarian Nordic A/S Methods and compositions for enhancing vaccine immune responses
JP2019500907A (ja) 2016-01-08 2019-01-17 ジオバックス・インコーポレイテッド 腫瘍関連抗原に対する免疫応答を誘起するための組成物及び方法
WO2019038388A1 (en) 2017-08-24 2019-02-28 Bavarian Nordic A/S POLYTHERAPY FOR THE TREATMENT OF CANCER BY INTRAVENOUS ADMINISTRATION OF RECOMBINANT MVA AND ANTIBODY
WO2020104531A1 (en) 2018-11-20 2020-05-28 Bavarian Nordic A/S Therapy for treating cancer with an intratumoral and/or intravenous administration of a recombinant mva encoding 4-1bbl (cd137l) and/or cd40l

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MX2022005601A (es) 2022-08-15
JP2023503858A (ja) 2023-02-01
EP4061404A1 (en) 2022-09-28
CA3159666A1 (en) 2021-05-27
KR20220116191A (ko) 2022-08-22
WO2021099572A1 (en) 2021-05-27
IL293012A (en) 2022-07-01
BR112022009797A2 (pt) 2022-08-16
CN114929268A (zh) 2022-08-19
AU2020388973A1 (en) 2022-05-26
US20230059344A1 (en) 2023-02-23

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