JP7661248B2 - スルホニル尿素誘導体及びその使用 - Google Patents
スルホニル尿素誘導体及びその使用 Download PDFInfo
- Publication number
- JP7661248B2 JP7661248B2 JP2021573384A JP2021573384A JP7661248B2 JP 7661248 B2 JP7661248 B2 JP 7661248B2 JP 2021573384 A JP2021573384 A JP 2021573384A JP 2021573384 A JP2021573384 A JP 2021573384A JP 7661248 B2 JP7661248 B2 JP 7661248B2
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- optionally substituted
- compound
- haloalkyl
- disease
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Peptides Or Proteins (AREA)
- Enzymes And Modification Thereof (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962860664P | 2019-06-12 | 2019-06-12 | |
| US62/860,664 | 2019-06-12 | ||
| PCT/EP2020/066185 WO2020249664A1 (en) | 2019-06-12 | 2020-06-11 | Sulfonylurea derivatives and uses thereof |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| JP2022536160A JP2022536160A (ja) | 2022-08-12 |
| JP2022536160A5 JP2022536160A5 (https=) | 2023-06-20 |
| JPWO2020249664A5 JPWO2020249664A5 (https=) | 2023-06-20 |
| JP7661248B2 true JP7661248B2 (ja) | 2025-04-14 |
Family
ID=71108562
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021573384A Active JP7661248B2 (ja) | 2019-06-12 | 2020-06-11 | スルホニル尿素誘導体及びその使用 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20230083495A1 (https=) |
| EP (1) | EP3983407B1 (https=) |
| JP (1) | JP7661248B2 (https=) |
| CN (1) | CN114222739B (https=) |
| ES (1) | ES3056339T3 (https=) |
| WO (1) | WO2020249664A1 (https=) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB201721185D0 (en) | 2017-12-18 | 2018-01-31 | Nodthera Ltd | Sulphonyl urea derivatives |
| PL3983387T3 (pl) | 2019-06-12 | 2024-08-19 | NodThera Limited | Pochodne sulfonylomocznika i ich zastosowania |
| CN117279903A (zh) * | 2021-02-10 | 2023-12-22 | 杭州英创医药科技有限公司 | 作为nlrp3抑制剂的化合物 |
| EP4729514A1 (en) | 2023-06-14 | 2026-04-22 | Haisco Pharmaceutical Group Co., Ltd. | Bicyclic derivative parp inhibitor and use thereof |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2018015445A1 (en) | 2016-07-20 | 2018-01-25 | NodThera Limited | Sulfonyl urea derivatives and their use in the control of interleukin-1 activity |
| JP2019512009A (ja) | 2016-02-16 | 2019-05-09 | ザ・ユニバーシティ・オブ・クイーンズランド | スルホニルウレアおよび関連化合物ならびにこれらの利用 |
| WO2020035464A1 (en) | 2018-08-15 | 2020-02-20 | Inflazome Limited | Novel sulfonamideurea compounds |
| WO2020035466A1 (en) | 2018-08-15 | 2020-02-20 | Inflazome Limited | Novel sulfoneurea compounds |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4522811A (en) | 1982-07-08 | 1985-06-11 | Syntex (U.S.A.) Inc. | Serial injection of muramyldipeptides and liposomes enhances the anti-infective activity of muramyldipeptides |
| JPS60214785A (ja) * | 1984-03-27 | 1985-10-28 | Nissan Chem Ind Ltd | ピラゾ−ルスルホニルウレア誘導体、および植物生長調節剤または除草剤 |
| DE4039734A1 (de) * | 1990-12-13 | 1992-06-17 | Basf Ag | Substituierte 2-aminothiophene enthaltende herbizide mittel |
| DE4217719A1 (de) * | 1992-05-29 | 1993-12-02 | Bayer Ag | Zweifach heterocyclisch substituierte Sulfonylamino(thio)carbonylverbindungen |
| JP3355237B2 (ja) * | 1993-10-15 | 2002-12-09 | 呉羽化学工業株式会社 | Ｎ−（置換アミノ）ピロール誘導体、その製造方法及び除草剤 |
| JPH0827147A (ja) * | 1994-07-20 | 1996-01-30 | Kureha Chem Ind Co Ltd | Ｎ−（置換アミノ）イミド誘導体、その製造方法及び除草剤 |
| US5763263A (en) | 1995-11-27 | 1998-06-09 | Dehlinger; Peter J. | Method and apparatus for producing position addressable combinatorial libraries |
| GB201721185D0 (en) * | 2017-12-18 | 2018-01-31 | Nodthera Ltd | Sulphonyl urea derivatives |
-
2020
- 2020-06-11 JP JP2021573384A patent/JP7661248B2/ja active Active
- 2020-06-11 EP EP20733705.6A patent/EP3983407B1/en active Active
- 2020-06-11 ES ES20733705T patent/ES3056339T3/es active Active
- 2020-06-11 US US17/618,188 patent/US20230083495A1/en active Pending
- 2020-06-11 WO PCT/EP2020/066185 patent/WO2020249664A1/en not_active Ceased
- 2020-06-11 CN CN202080057088.4A patent/CN114222739B/zh active Active
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2019512009A (ja) | 2016-02-16 | 2019-05-09 | ザ・ユニバーシティ・オブ・クイーンズランド | スルホニルウレアおよび関連化合物ならびにこれらの利用 |
| WO2018015445A1 (en) | 2016-07-20 | 2018-01-25 | NodThera Limited | Sulfonyl urea derivatives and their use in the control of interleukin-1 activity |
| WO2020035464A1 (en) | 2018-08-15 | 2020-02-20 | Inflazome Limited | Novel sulfonamideurea compounds |
| WO2020035466A1 (en) | 2018-08-15 | 2020-02-20 | Inflazome Limited | Novel sulfoneurea compounds |
Also Published As
| Publication number | Publication date |
|---|---|
| ES3056339T3 (en) | 2026-02-19 |
| US20230083495A1 (en) | 2023-03-16 |
| JP2022536160A (ja) | 2022-08-12 |
| EP3983407A1 (en) | 2022-04-20 |
| CN114222739A (zh) | 2022-03-22 |
| WO2020249664A1 (en) | 2020-12-17 |
| EP3983407C0 (en) | 2025-11-12 |
| CN114222739B (zh) | 2025-02-11 |
| EP3983407B1 (en) | 2025-11-12 |
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