JP7657774B2 - 191p4d12タンパク質に結合する抗体薬物コンジュゲート(adc)による癌の治療方法 - Google Patents

191p4d12タンパク質に結合する抗体薬物コンジュゲート(adc)による癌の治療方法 Download PDF

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JP7657774B2
JP7657774B2 JP2022508480A JP2022508480A JP7657774B2 JP 7657774 B2 JP7657774 B2 JP 7657774B2 JP 2022508480 A JP2022508480 A JP 2022508480A JP 2022508480 A JP2022508480 A JP 2022508480A JP 7657774 B2 JP7657774 B2 JP 7657774B2
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antibody
amino acid
antigen
cdr
acid sequence
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オイウェイル オー. アビドイェ
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アジェンシス,インコーポレイテッド
シージェン インコーポレイテッド
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    • A61K47/6889Conjugates wherein the antibody being the modifying agent and wherein the linker, binder or spacer confers particular properties to the conjugates, e.g. peptidic enzyme-labile linkers or acid-labile linkers, providing for an acid-labile immuno conjugate wherein the drug may be released from its antibody conjugated part in an acidic, e.g. tumoural or environment
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JP2022508480A 2019-08-13 2020-08-10 191p4d12タンパク質に結合する抗体薬物コンジュゲート(adc)による癌の治療方法 Active JP7657774B2 (ja)

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JP2025051867A JP2025106332A (ja) 2019-08-13 2025-03-26 191p4d12タンパク質に結合する抗体薬物コンジュゲート(adc)による癌の治療方法

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US201962886270P 2019-08-13 2019-08-13
US62/886,270 2019-08-13
PCT/US2020/045567 WO2021030240A1 (en) 2019-08-13 2020-08-10 Treatment of cancers with antibody drug conjugates (adc) that bind to 191p4d12 proteins

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JP2025051867A Withdrawn JP2025106332A (ja) 2019-08-13 2025-03-26 191p4d12タンパク質に結合する抗体薬物コンジュゲート(adc)による癌の治療方法

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EP (1) EP4013795A4 (https=)
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CN (1) CN114901690A (https=)
AU (1) AU2020329761A1 (https=)
BR (1) BR112022002391A2 (https=)
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AU2019392090A1 (en) 2018-12-03 2021-06-17 Agensys, Inc. Pharmaceutical compositions comprising anti-191P4D12 antibody drug conjugates and methods of use thereof
EP4143344A1 (en) * 2020-04-27 2023-03-08 Agendia N.V. Treatment of her2 negative, mammaprint high risk 2 breast cancer
IL302006A (en) * 2020-10-11 2023-06-01 Agensys Inc Methods for treating cancer with antibody-drug conjugates (ADC) that bind to proteins 191P4D12
EP4301774A4 (en) * 2021-03-03 2025-08-13 Dragonfly Therapeutics Inc METHODS OF TREATING CANCER USING MULTI-SPECIFIC BINDING PROTEINS THAT BIND TO NKG2D, CD16, AND A TUMOR-ASSOCIATED ANTIGEN
WO2024012536A1 (zh) * 2022-07-14 2024-01-18 百奥泰生物制药股份有限公司 抗Nectin-4抗体、其抗体药物偶联物及应用
JP2026508244A (ja) 2023-02-22 2026-03-10 ナンジング リーズ バイオラブズ シーオー., エルティーディー. 抗Nectin-4抗体及びそれを含む多重特異性抗体
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