JP7649504B2 - マラリアワクチン及びマラリア予防・治療方法 - Google Patents

マラリアワクチン及びマラリア予防・治療方法 Download PDF

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JP7649504B2
JP7649504B2 JP2024501407A JP2024501407A JP7649504B2 JP 7649504 B2 JP7649504 B2 JP 7649504B2 JP 2024501407 A JP2024501407 A JP 2024501407A JP 2024501407 A JP2024501407 A JP 2024501407A JP 7649504 B2 JP7649504 B2 JP 7649504B2
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csp
gene encoding
amino acid
acid sequence
malaria
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JPWO2023157880A1 (https=
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栄人 吉田
光洋 伊從
壽利 志田
浩明 水上
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Kanazawa University NUC
Jichi Medical University
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    • A—HUMAN NECESSITIES
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    • A—HUMAN NECESSITIES
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    • A61K39/002—Protozoa antigens
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    • A—HUMAN NECESSITIES
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K39/12—Viral antigens
    • A61K39/23—Parvoviridae, e.g. feline panleukopenia virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/275—Poxviridae, e.g. avipoxvirus
    • A61K39/285—Vaccinia virus or variola virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A61P33/06—Antimalarials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/44—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from protozoa
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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86—Viral vectors
    • C12N15/863—Poxviral vectors, e.g. entomopoxvirus
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86—Viral vectors
    • C12N15/864—Parvoviral vectors, e.g. parvovirus, densovirus
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Health & Medical Sciences (AREA)
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  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
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  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Mycology (AREA)
  • Biochemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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  • Physics & Mathematics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
JP2024501407A 2022-02-18 2023-02-15 マラリアワクチン及びマラリア予防・治療方法 Active JP7649504B2 (ja)

Applications Claiming Priority (5)

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JP2022024221 2022-02-18
JP2022024221 2022-02-18
JP2022131078 2022-08-19
JP2022131078 2022-08-19
PCT/JP2023/005232 WO2023157880A1 (ja) 2022-02-18 2023-02-15 マラリアワクチン及びマラリア予防・治療方法

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JP7649504B2 true JP7649504B2 (ja) 2025-03-21

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Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007091624A1 (ja) 2006-02-09 2007-08-16 Educational Foundation Jichi Medical University 新規ウイルスベクター
JP2010535466A (ja) 2007-08-07 2010-11-25 学校法人自治医科大学 新規ウイルスベクター
WO2016059911A1 (ja) 2014-10-17 2016-04-21 国立大学法人金沢大学 マラリアワクチン
JP2017502674A (ja) 2013-12-30 2017-01-26 ヴイ−コア テクノロジーズ インコーポレイテッド ポックスウィルス−プラスモジウム組換え体、こうした組換え体を含む組成物、該組換え体の使用、および該組換え体を作製し、および用いる方法。
JP2017512498A (ja) 2014-03-28 2017-05-25 フラウンホーファーゲゼルシャフト ツール フォルデルング デル アンゲヴァンテン フォルシユング エー．フアー． 複数成分複数段階マラリアワクチン
JP2017527293A (ja) 2014-09-08 2017-09-21 フラウンホーファーゲゼルシャフト ツール フォルデルング デル アンゲヴァンテン フォルシユング エー．フアー． 三成分多段階マラリアワクチン
JP2019151617A (ja) 2018-03-02 2019-09-12 国立大学法人金沢大学 マラリアワクチン

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007091624A1 (ja) 2006-02-09 2007-08-16 Educational Foundation Jichi Medical University 新規ウイルスベクター
JP2010535466A (ja) 2007-08-07 2010-11-25 学校法人自治医科大学 新規ウイルスベクター
JP2017502674A (ja) 2013-12-30 2017-01-26 ヴイ−コア テクノロジーズ インコーポレイテッド ポックスウィルス−プラスモジウム組換え体、こうした組換え体を含む組成物、該組換え体の使用、および該組換え体を作製し、および用いる方法。
JP2017512498A (ja) 2014-03-28 2017-05-25 フラウンホーファーゲゼルシャフト ツール フォルデルング デル アンゲヴァンテン フォルシユング エー．フアー． 複数成分複数段階マラリアワクチン
JP2017527293A (ja) 2014-09-08 2017-09-21 フラウンホーファーゲゼルシャフト ツール フォルデルング デル アンゲヴァンテン フォルシユング エー．フアー． 三成分多段階マラリアワクチン
WO2016059911A1 (ja) 2014-10-17 2016-04-21 国立大学法人金沢大学 マラリアワクチン
JP2019151617A (ja) 2018-03-02 2019-09-12 国立大学法人金沢大学 マラリアワクチン

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
BAUZA K. et al.，Efficacy of a Plasmodium vivax Malaria Vaccine Using ChAd63 and Modified Vaccinia Ankara Expressing，Infection and Immunity，2014年，Vol.82, No.3，p.1277-1286
HILL A. V. S. et al，Prime-boost vectored malaria vaccines: progress and prospects，Human Vaccines，2010年，Vol.6, No.1，p.78-83

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WO2023157880A1 (ja) 2023-08-24

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