JP7637058B2 - Ｇｒｎ関連成人発症性神経変性の治療のための組換えアデノ随伴ウイルス - Google Patents

Ｇｒｎ関連成人発症性神経変性の治療のための組換えアデノ随伴ウイルス Download PDF

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JP7637058B2
JP7637058B2 JP2021549291A JP2021549291A JP7637058B2 JP 7637058 B2 JP7637058 B2 JP 7637058B2 JP 2021549291 A JP2021549291 A JP 2021549291A JP 2021549291 A JP2021549291 A JP 2021549291A JP 7637058 B2 JP7637058 B2 JP 7637058B2
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ヒンデラー，クリスチャン
ミラー，ニムロッド
ウイルソン，ジェームス・エム
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ザ・トラステイーズ・オブ・ザ・ユニバーシテイ・オブ・ペンシルベニア
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    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86—Viral vectors
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
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    • A61K9/0012—Galenical forms characterised by the site of application
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    • A61P25/00—Drugs for disorders of the nervous system
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    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • C12N2750/00011—Details
    • C12N2750/14011—Parvoviridae
    • C12N2750/14111—Dependovirus, e.g. adenoassociated viruses
    • C12N2750/14141—Use of virus, viral particle or viral elements as a vector
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    • C12N2750/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssDNA viruses
    • C12N2750/00011—Details
    • C12N2750/14011—Parvoviridae
    • C12N2750/14111—Dependovirus, e.g. adenoassociated viruses
    • C12N2750/14171—Demonstrated in vivo effect

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JP2021549291A 2019-02-22 2020-02-21 Ｇｒｎ関連成人発症性神経変性の治療のための組換えアデノ随伴ウイルス Active JP7637058B2 (ja)

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JP2025022078A JP2025081439A (ja) 2019-02-22 2025-02-14 Ｇｒｎ関連成人発症性神経変性の治療のための組換えアデノ随伴ウイルス

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US201962809329P 2019-02-22 2019-02-22
US62/809,329 2019-02-22
US201962923812P 2019-10-21 2019-10-21
US62/923,812 2019-10-21
US202062969108P 2020-02-02 2020-02-02
US62/969,108 2020-02-02
PCT/US2020/019149 WO2020172490A1 (en) 2019-02-22 2020-02-21 Recombinant adeno-associated virus for treatment of grn-associated adult-onset neurodegeneration

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JP2025022078A Pending JP2025081439A (ja) 2019-02-22 2025-02-14 Ｇｒｎ関連成人発症性神経変性の治療のための組換えアデノ随伴ウイルス

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AU (1) AU2020225472A1 (enExample)
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IL (1) IL285654A (enExample)
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PE (1) PE20211819A1 (enExample)
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EP4473123A4 (en) * 2022-02-01 2026-03-11 Shape Therapeutics Inc STABLE CELL LINES FOR INDUCIBLE VAAR VIRION PRODUCTION
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TW202548022A (zh) * 2024-03-03 2025-12-16 美商帕西奇生物公司 用於治療神經退化性病症之重組腺相關病毒

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JP2023540054A (ja) * 2020-08-26 2023-09-21 ザ・トラステイーズ・オブ・ザ・ユニバーシテイ・オブ・ペンシルベニア Ｇｒｎ関連成人発症性神経変性の治療のための組換えアデノ随伴ウイルス

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PE20211819A1 (es) 2021-09-14
US12416017B2 (en) 2025-09-16
JP2025081439A (ja) 2025-05-27
AU2020225472A1 (en) 2021-08-26
TW202045730A (zh) 2020-12-16
US20260049335A1 (en) 2026-02-19
MX2021010134A (es) 2021-09-23
CA3129672A1 (en) 2020-08-27
EP3927381A1 (en) 2021-12-29
IL285654A (en) 2021-09-30
BR112021015817A2 (pt) 2021-10-13
CO2021011040A2 (es) 2021-09-09
CN113710281A (zh) 2021-11-26
KR20210131370A (ko) 2021-11-02
WO2020172490A1 (en) 2020-08-27
US20220136008A1 (en) 2022-05-05
JP2022523766A (ja) 2022-04-26
CL2021002172A1 (es) 2022-02-11
SG11202108504YA (en) 2021-09-29

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