JP7615021B2 - 遺伝子発現の選択的スプライシング調節および治療方法 - Google Patents

遺伝子発現の選択的スプライシング調節および治療方法 Download PDF

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JP7615021B2
JP7615021B2 JP2021506457A JP2021506457A JP7615021B2 JP 7615021 B2 JP7615021 B2 JP 7615021B2 JP 2021506457 A JP2021506457 A JP 2021506457A JP 2021506457 A JP2021506457 A JP 2021506457A JP 7615021 B2 JP7615021 B2 JP 7615021B2
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protein
expression
pyridazin
rna
methyl
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JP2021532812A (ja
JP2021532812A5 (OSRAM
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ビヴァリー エル． ダヴィッドソン
アレハンドロ マス モンティス
アミール アル ハンドリー
ポール ティー． ラナム
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Childrens Hospital of Philadelphia CHOP
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JP2021506457A 2018-08-07 2019-08-07 遺伝子発現の選択的スプライシング調節および治療方法 Active JP7615021B2 (ja)

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US201862715756P 2018-08-07 2018-08-07
US62/715,756 2018-08-07
US201962837701P 2019-04-23 2019-04-23
US62/837,701 2019-04-23
US201962838223P 2019-04-24 2019-04-24
US62/838,223 2019-04-24
US201962872417P 2019-07-10 2019-07-10
US62/872,417 2019-07-10
PCT/US2019/045401 WO2020033473A1 (en) 2018-08-07 2019-08-07 Alternative splicing regulation of gene expression and therapeutic methods

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CN (1) CN112805009A (OSRAM)
AU (1) AU2019317573A1 (OSRAM)
CA (1) CA3108293A1 (OSRAM)
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JP7013753B2 (ja) * 2017-09-15 2022-02-01 株式会社三洋物産 遊技機
JP7013754B2 (ja) * 2017-09-15 2022-02-01 株式会社三洋物産 遊技機
JP2022545378A (ja) * 2019-08-15 2022-10-27 ザ・チルドレンズ・ホスピタル・オブ・フィラデルフィア ＳＣＡ１の治療のための、導入遺伝子およびイントロン由来ｍｉＲＮＡを組み合わせた治療法
EP4051280A1 (en) * 2019-11-01 2022-09-07 Novartis AG The use of a splicing modulator for a treatment slowing progression of huntington's disease
US20230340498A1 (en) * 2020-02-12 2023-10-26 The Children's Hospital Of Philadelphia Compositions and methods for inducible alternative splicing regulation of gene expression
JP2020151570A (ja) * 2020-06-24 2020-09-24 株式会社三洋物産 遊技機
EP4294459A4 (en) * 2021-02-19 2025-06-18 University Of Florida Research Foundation, Incorporated Methods and compositions to confer regulation to gene therapy cargoes by heterologous use of alternative splicing cassettes
JP2021079225A (ja) * 2021-03-01 2021-05-27 株式会社三洋物産 遊技機
JP2021087833A (ja) * 2021-03-01 2021-06-10 株式会社三洋物産 遊技機
JP2021087836A (ja) * 2021-03-01 2021-06-10 株式会社三洋物産 遊技機
JP2021079226A (ja) * 2021-03-01 2021-05-27 株式会社三洋物産 遊技機
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