JP7601760B2 - リアルタイム予測のためのラマン分光モデルの自動校正及び自動保守 - Google Patents
リアルタイム予測のためのラマン分光モデルの自動校正及び自動保守 Download PDFInfo
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- JP7601760B2 JP7601760B2 JP2021521530A JP2021521530A JP7601760B2 JP 7601760 B2 JP7601760 B2 JP 7601760B2 JP 2021521530 A JP2021521530 A JP 2021521530A JP 2021521530 A JP2021521530 A JP 2021521530A JP 7601760 B2 JP7601760 B2 JP 7601760B2
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/65—Raman scattering
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
- C12M41/48—Automatic or computerized control
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01J—MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
- G01J3/00—Spectrometry; Spectrophotometry; Monochromators; Measuring colours
- G01J3/28—Investigating the spectrum
- G01J3/44—Raman spectrometry; Scattering spectrometry ; Fluorescence spectrometry
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
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- G—PHYSICS
- G06—COMPUTING OR CALCULATING; COUNTING
- G06N—COMPUTING ARRANGEMENTS BASED ON SPECIFIC COMPUTATIONAL MODELS
- G06N20/00—Machine learning
-
- G—PHYSICS
- G06—COMPUTING OR CALCULATING; COUNTING
- G06N—COMPUTING ARRANGEMENTS BASED ON SPECIFIC COMPUTATIONAL MODELS
- G06N5/00—Computing arrangements using knowledge-based models
- G06N5/04—Inference or reasoning models
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B40/00—ICT specially adapted for biostatistics; ICT specially adapted for bioinformatics-related machine learning or data mining, e.g. knowledge discovery or pattern finding
- G16B40/20—Supervised data analysis
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B5/00—ICT specially adapted for modelling or simulations in systems biology, e.g. gene-regulatory networks, protein interaction networks or metabolic networks
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/84—Systems specially adapted for particular applications
- G01N2021/8411—Application to online plant, process monitoring
- G01N2021/8416—Application to online plant, process monitoring and process controlling, not otherwise provided for
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2201/00—Features of devices classified in G01N21/00
- G01N2201/12—Circuits of general importance; Signal processing
- G01N2201/127—Calibration; base line adjustment; drift compensation
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2201/00—Features of devices classified in G01N21/00
- G01N2201/12—Circuits of general importance; Signal processing
- G01N2201/129—Using chemometrical methods
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- Engineering & Computer Science (AREA)
- Health & Medical Sciences (AREA)
- Physics & Mathematics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Theoretical Computer Science (AREA)
- General Physics & Mathematics (AREA)
- General Health & Medical Sciences (AREA)
- Software Systems (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Analytical Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Data Mining & Analysis (AREA)
- Medical Informatics (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Artificial Intelligence (AREA)
- Evolutionary Computation (AREA)
- Pathology (AREA)
- Immunology (AREA)
- Biotechnology (AREA)
- Computing Systems (AREA)
- Mathematical Physics (AREA)
- Computer Vision & Pattern Recognition (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Evolutionary Biology (AREA)
- Biophysics (AREA)
- Bioinformatics & Computational Biology (AREA)
- Organic Chemistry (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Urology & Nephrology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Hematology (AREA)
- Computational Linguistics (AREA)
- Epidemiology (AREA)
- Databases & Information Systems (AREA)
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862749359P | 2018-10-23 | 2018-10-23 | |
| US62/749,359 | 2018-10-23 | ||
| US201962833044P | 2019-04-12 | 2019-04-12 | |
| US62/833,044 | 2019-04-12 | ||
| US201962864565P | 2019-06-21 | 2019-06-21 | |
| US62/864,565 | 2019-06-21 | ||
| PCT/US2019/057513 WO2020086635A1 (en) | 2018-10-23 | 2019-10-23 | Automatic calibration and automatic maintenance of raman spectroscopic models for real-time predictions |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2022512775A JP2022512775A (ja) | 2022-02-07 |
| JP2022512775A5 JP2022512775A5 (https=) | 2022-10-26 |
| JP7601760B2 true JP7601760B2 (ja) | 2024-12-17 |
Family
ID=70331744
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021521530A Active JP7601760B2 (ja) | 2018-10-23 | 2019-10-23 | リアルタイム予測のためのラマン分光モデルの自動校正及び自動保守 |
Country Status (21)
| Country | Link |
|---|---|
| US (1) | US20220128474A1 (https=) |
| EP (1) | EP3870957B1 (https=) |
| JP (1) | JP7601760B2 (https=) |
| KR (1) | KR20210078531A (https=) |
| CN (1) | CN112912716B (https=) |
| AU (2) | AU2019365102A1 (https=) |
| CA (1) | CA3115296A1 (https=) |
| CL (1) | CL2021001024A1 (https=) |
| DK (1) | DK3870957T3 (https=) |
| ES (1) | ES3041713T3 (https=) |
| FI (1) | FI3870957T3 (https=) |
| HU (1) | HUE072452T2 (https=) |
| IL (1) | IL281977B2 (https=) |
| LT (1) | LT3870957T (https=) |
| MX (1) | MX2021004510A (https=) |
| PL (1) | PL3870957T3 (https=) |
| PT (1) | PT3870957T (https=) |
| SG (1) | SG11202103232WA (https=) |
| SI (1) | SI3870957T1 (https=) |
| TW (1) | TWI844570B (https=) |
| WO (1) | WO2020086635A1 (https=) |
Families Citing this family (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN119264211A (zh) | 2018-08-27 | 2025-01-07 | 瑞泽恩制药公司 | 拉曼光谱在下游纯化中的应用 |
| CN114207593B (zh) * | 2019-06-10 | 2025-10-21 | 沃特世科技爱尔兰有限公司 | 用于分析仪器性能诊断的技术 |
| WO2021108453A1 (en) * | 2019-11-26 | 2021-06-03 | Thermo Finnigan Llc | Remote monitoring, troubleshooting and service scheduling of analytical apparatuses |
| CN116457453A (zh) * | 2020-10-01 | 2023-07-18 | 美国安进公司 | 细胞培养的预测建模和控制 |
| US20220138557A1 (en) * | 2020-11-04 | 2022-05-05 | Adobe Inc. | Deep Hybrid Graph-Based Forecasting Systems |
| US20210117841A1 (en) * | 2020-12-23 | 2021-04-22 | Intel Corporation | Methods, apparatus, and articles of manufacture to improve automated machine learning |
| DE102021100531B3 (de) * | 2021-01-13 | 2022-03-31 | BioThera Institut GmbH | Apparatur zum Steuern eines Prozesses sowie zugehöriges Steuerungsverfahren |
| JP2024525133A (ja) * | 2021-06-09 | 2024-07-10 | アムジエン・インコーポレーテツド | 細胞培養物の血中血球容積の評価 |
| WO2022269464A1 (en) * | 2021-06-20 | 2022-12-29 | The State Of Israel, Ministry Of Agriculture & Rural Development Agricultural Research Organization (Aro) | Raman spectroscopy method and system for monitoring invasive species in algal bioreactors |
| EP4390379A4 (en) * | 2021-09-30 | 2025-01-01 | FUJIFILM Corporation | LEARNING DATA ACQUISITION METHOD, LEARNING DATA ACQUISITION SYSTEM, SOFT SENSOR CONSTRUCTION METHOD, SOFT SENSOR, AND LEARNING DATA |
| JP2025500732A (ja) | 2021-10-27 | 2025-01-15 | アムジエン・インコーポレーテツド | 分光法を使用して薬剤を監視するための深層学習ベースの予測 |
| JPWO2023090015A1 (https=) * | 2021-11-22 | 2023-05-25 | ||
| JP7783091B2 (ja) * | 2022-02-25 | 2025-12-09 | 株式会社日立製作所 | 評価システム及び評価方法 |
| TW202346567A (zh) * | 2022-03-01 | 2023-12-01 | 美商安進公司 | 用於控制細胞培養之混合預測建模 |
| CN115308102B (zh) * | 2022-05-19 | 2025-07-01 | 芬欧汇川(中国)有限公司 | 纸张透气度测量方法以及纸张透气度测量系统 |
| US20240044801A1 (en) * | 2022-07-26 | 2024-02-08 | Thermo Scientific Portable Analytical Instruments Inc. | Autochemometric scientific instrument support systems |
| CA3265250A1 (en) * | 2022-08-29 | 2024-03-07 | Amgen Inc. | PREDICTIVE MODEL FOR EVALUATING PROCESSING TIME IMPACTS |
| EP4581349A1 (en) * | 2022-08-29 | 2025-07-09 | Büchi Labortechnik AG | Methods for providing a predictive model for spectroscopy and calibrating a spectroscopic device |
| CA3265356A1 (en) | 2022-09-14 | 2024-03-21 | Amgen Inc. | JUST-IN-TIME LEARNING WITH VARIATIONAL AUTOCODER FOR MONITORING AND/OR CONTROL OF CELL CULTURE PROCESSES |
| JP2026502096A (ja) * | 2022-12-12 | 2026-01-21 | ジェネンテック, インコーポレイテッド | 限外濾過/透析濾過(uf/df)コンディショニングおよび希釈プロセスのリアルタイム自動モニタリングと制御 |
| WO2024188962A1 (en) * | 2023-03-14 | 2024-09-19 | Katholieke Universiteit Leuven | Spectrum prediction methods for chemical processes |
| WO2024202620A1 (ja) | 2023-03-31 | 2024-10-03 | 富士フイルム株式会社 | 品質監視装置、品質監視装置の作動方法、および品質監視装置の作動プログラム |
| KR20250023079A (ko) | 2023-08-09 | 2025-02-18 | 주식회사 엘지화학 | 발효공정의 생성량 예측 시스템 및 방법 |
| CN117571684A (zh) * | 2023-11-20 | 2024-02-20 | 无锡药明生物技术股份有限公司 | 细胞培养液代谢物浓度确定方法、装置、设备和介质 |
| WO2025114830A1 (en) * | 2023-11-27 | 2025-06-05 | Avant Meats Company Limited | Control system and method for a perpetual automated bioprocessing system |
| WO2025132566A1 (en) | 2023-12-21 | 2025-06-26 | Boehringer Ingelheim International Gmbh | Measuring arrangement and method for analyzing a fluidic sample |
| CN118819056B (zh) * | 2024-09-19 | 2024-12-31 | 天津医学高等专科学校(天津市护士学校) | 一种黄芩细胞悬浮培养优化控制系统 |
| CN118820281B (zh) * | 2024-09-19 | 2024-12-31 | 之江实验室 | 光谱数据库查询模型构建方法以及光谱数据库查询方法 |
| EP4715492A1 (en) * | 2024-09-20 | 2026-03-25 | Sartorius Stedim Data Analytics AB | Monitoring and/or controlling a chemical and/or biological process |
| CN119223939B (zh) * | 2024-11-28 | 2025-04-01 | 合肥金星智控科技股份有限公司 | 基于libs的物料检测模型的自适应校准方法及装置 |
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2019
- 2019-10-23 MX MX2021004510A patent/MX2021004510A/es unknown
- 2019-10-23 ES ES19848831T patent/ES3041713T3/es active Active
- 2019-10-23 CN CN201980068986.7A patent/CN112912716B/zh active Active
- 2019-10-23 CA CA3115296A patent/CA3115296A1/en active Pending
- 2019-10-23 SG SG11202103232WA patent/SG11202103232WA/en unknown
- 2019-10-23 HU HUE19848831A patent/HUE072452T2/hu unknown
- 2019-10-23 PL PL19848831.4T patent/PL3870957T3/pl unknown
- 2019-10-23 LT LTEPPCT/US2019/057513T patent/LT3870957T/lt unknown
- 2019-10-23 US US17/284,551 patent/US20220128474A1/en active Pending
- 2019-10-23 SI SI201930957T patent/SI3870957T1/sl unknown
- 2019-10-23 JP JP2021521530A patent/JP7601760B2/ja active Active
- 2019-10-23 IL IL281977A patent/IL281977B2/en unknown
- 2019-10-23 PT PT198488314T patent/PT3870957T/pt unknown
- 2019-10-23 TW TW108138146A patent/TWI844570B/zh active
- 2019-10-23 AU AU2019365102A patent/AU2019365102A1/en not_active Abandoned
- 2019-10-23 EP EP19848831.4A patent/EP3870957B1/en active Active
- 2019-10-23 DK DK19848831.4T patent/DK3870957T3/da active
- 2019-10-23 KR KR1020217015045A patent/KR20210078531A/ko active Pending
- 2019-10-23 FI FIEP19848831.4T patent/FI3870957T3/fi active
- 2019-10-23 WO PCT/US2019/057513 patent/WO2020086635A1/en not_active Ceased
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2021
- 2021-04-22 CL CL2021001024A patent/CL2021001024A1/es unknown
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2025
- 2025-07-11 AU AU2025205401A patent/AU2025205401A1/en active Pending
Patent Citations (6)
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| US20120072122A1 (en) | 2005-06-09 | 2012-03-22 | Chemimage Corporation | Forensic Integrated Search Technology |
| US20080244251A1 (en) | 2007-03-29 | 2008-10-02 | Khipu Systems Limited | Predictive model implementation system and methodology |
| US20090119244A1 (en) | 2007-10-30 | 2009-05-07 | Chimenti Robert J | Bootstrap method for oil property prediction |
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| JP2015522249A (ja) | 2012-04-04 | 2015-08-06 | ベーイーオー・メリュー | 分光分析および構造化分類による微生物の同定 |
| US20130311136A1 (en) | 2012-05-18 | 2013-11-21 | Mustard Tree Instruments, Llc | Rule-Based Sample Verification and Chemical Monitoring Methodology |
Also Published As
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| CN112912716A (zh) | 2021-06-04 |
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| KR20210078531A (ko) | 2021-06-28 |
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| JP2022512775A (ja) | 2022-02-07 |
| PL3870957T3 (pl) | 2025-11-17 |
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| TWI844570B (zh) | 2024-06-11 |
| BR112021007611A2 (pt) | 2021-07-27 |
| TW202033949A (zh) | 2020-09-16 |
| CL2021001024A1 (es) | 2021-09-24 |
| PT3870957T (pt) | 2025-09-01 |
| CN112912716B (zh) | 2025-04-11 |
| SI3870957T1 (sl) | 2025-10-30 |
| DK3870957T3 (da) | 2025-09-29 |
| MX2021004510A (es) | 2021-06-08 |
| FI3870957T3 (fi) | 2025-09-30 |
| CA3115296A1 (en) | 2020-04-30 |
| EP3870957A1 (en) | 2021-09-01 |
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