JP7546104B2 - ５－ヘテロアリール－１ｈ－ピラゾール－３－アミン誘導体からなる医薬 - Google Patents

５－ヘテロアリール－１ｈ－ピラゾール－３－アミン誘導体からなる医薬 Download PDF

Info

Publication number
JP7546104B2
JP7546104B2 JP2023087014A JP2023087014A JP7546104B2 JP 7546104 B2 JP7546104 B2 JP 7546104B2 JP 2023087014 A JP2023087014 A JP 2023087014A JP 2023087014 A JP2023087014 A JP 2023087014A JP 7546104 B2 JP7546104 B2 JP 7546104B2
Authority
JP
Japan
Prior art keywords
cancer
group
item
pharmaceutical composition
compound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
JP2023087014A
Other languages
English (en)
Japanese (ja)
Other versions
JP2023174607A (ja
JP2023174607A5 (enExample
Inventor
正児 上岡
仁志 坂
誠 松岡
亘 広瀬
尚明 島田
健人 林
宏紀 楳原
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sumitomo Pharma Co Ltd
Original Assignee
Sumitomo Dainippon Pharma Co Ltd
Sumitomo Pharma Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sumitomo Dainippon Pharma Co Ltd, Sumitomo Pharma Co Ltd filed Critical Sumitomo Dainippon Pharma Co Ltd
Publication of JP2023174607A publication Critical patent/JP2023174607A/ja
Publication of JP2023174607A5 publication Critical patent/JP2023174607A5/ja
Application granted granted Critical
Publication of JP7546104B2 publication Critical patent/JP7546104B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Images

Landscapes

  • Plural Heterocyclic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP2023087014A 2022-05-27 2023-05-26 ５－ヘテロアリール－１ｈ－ピラゾール－３－アミン誘導体からなる医薬 Active JP7546104B2 (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2022087171 2022-05-27
JP2022087171 2022-05-27

Publications (3)

Publication Number Publication Date
JP2023174607A JP2023174607A (ja) 2023-12-07
JP2023174607A5 JP2023174607A5 (enExample) 2024-03-11
JP7546104B2 true JP7546104B2 (ja) 2024-09-05

Family

ID=89031009

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2023087014A Active JP7546104B2 (ja) 2022-05-27 2023-05-26 ５－ヘテロアリール－１ｈ－ピラゾール－３－アミン誘導体からなる医薬

Country Status (1)

Country Link
JP (1) JP7546104B2 (enExample)

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2012512249A (ja) 2008-12-17 2012-05-31 イーライ リリー アンド カンパニー Ｃｈｋ１を阻害するために有用な化合物
JP2017508787A (ja) 2014-02-10 2017-03-30 カスカディアン セラピューティクス， インコーポレイテッド 医薬化合物
JP2018528172A (ja) 2015-07-23 2018-09-27 イーライ リリー アンド カンパニー 神経芽細胞腫及び／または軟部組織肉腫の処置における使用のためのｃｈｋ１／２阻害剤
JP2019509990A (ja) 2016-02-04 2019-04-11 ファーマエンジン インコーポレーテッドＰｈａｒｍａｅｎｇｉｎｅ， Ｉｎｃ． チェックポイントキナーゼ１（ｃｈｋ１）阻害剤として有用な３，５−二置換ピラゾール、並びにその調製及び用途

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA3200498A1 (en) * 2020-11-30 2022-06-02 Sumitomo Pharma Co., Ltd. 5-heteroaryl-1h-pyrazol-3-amine derivative

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2012512249A (ja) 2008-12-17 2012-05-31 イーライ リリー アンド カンパニー Ｃｈｋ１を阻害するために有用な化合物
JP2017508787A (ja) 2014-02-10 2017-03-30 カスカディアン セラピューティクス， インコーポレイテッド 医薬化合物
JP2018528172A (ja) 2015-07-23 2018-09-27 イーライ リリー アンド カンパニー 神経芽細胞腫及び／または軟部組織肉腫の処置における使用のためのｃｈｋ１／２阻害剤
JP2019509990A (ja) 2016-02-04 2019-04-11 ファーマエンジン インコーポレーテッドＰｈａｒｍａｅｎｇｉｎｅ， Ｉｎｃ． チェックポイントキナーゼ１（ｃｈｋ１）阻害剤として有用な３，５−二置換ピラゾール、並びにその調製及び用途

Also Published As

Publication number Publication date
JP2023174607A (ja) 2023-12-07

Similar Documents

Publication Publication Date Title
US12410154B2 (en) 5-heteroaryl-1H-pyrazol-3-amine derivative
US11787801B2 (en) Protein kinase inhibitors, preparation method and medical use thereof
US11564920B2 (en) 5-heteroaryl-1H-pyrazol-3-amine derivative
US20250352541A1 (en) Therapeutic for cancer refractory to immune checkpoint inhibitor
JP7546104B2 (ja) ５－ヘテロアリール－１ｈ－ピラゾール－３－アミン誘導体からなる医薬
EA048701B1 (ru) Производное 5-гетероарил-1h-пиразол-3-амина
HK40094126A (en) 5-heteroaryl-1h-pyrazol-3-amine derivative
US20250129049A1 (en) 1h-pyrazole-3-amine derivative having bicyclic backbone
HK40119491A (en) Therapeutic for cancer refractory to immune checkpoint inhibitor
EA049737B1 (ru) Производное 1h-пиразол-3-амина, имеющее бициклическую основную цепь
TW202146405A (zh) Cdk9抑制劑前體藥物及內封其之脂質體
HK40115947A (en) 1h-pyrazole-3-amine derivative having bicyclic backbone
CN118434726A (zh) 具有二环性骨架的1h-吡唑-3-胺衍生物
HK40107032A (en) Self degradation-type cdk9 inhibitor prodrug and liposome encapsulating same
KR20240051194A (ko) 자기 분해형 cdk9 저해제 프로드러그 및 그것을 내봉하는 리포솜
HK1260629B (en) 4-(3h-indol-5-yl)-n-(pyridin-2-yl)pyrimidin-2-amine derivatives as protein kinase inhibitors, preparation method and medical use thereof

Legal Events

Date Code Title Description
RD03 Notification of appointment of power of attorney

Free format text: JAPANESE INTERMEDIATE CODE: A7423

Effective date: 20230728

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20240229

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20240229

A871 Explanation of circumstances concerning accelerated examination

Free format text: JAPANESE INTERMEDIATE CODE: A871

Effective date: 20240229

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20240507

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20240527

TRDD Decision of grant or rejection written
A01 Written decision to grant a patent or to grant a registration (utility model)

Free format text: JAPANESE INTERMEDIATE CODE: A01

Effective date: 20240820

A61 First payment of annual fees (during grant procedure)

Free format text: JAPANESE INTERMEDIATE CODE: A61

Effective date: 20240826

R150 Certificate of patent or registration of utility model

Ref document number: 7546104

Country of ref document: JP

Free format text: JAPANESE INTERMEDIATE CODE: R150