JP7539836B2 - 哺乳類卵母細胞を裸化するためのマイクロ流体システムおよび方法 - Google Patents

哺乳類卵母細胞を裸化するためのマイクロ流体システムおよび方法 Download PDF

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JP7539836B2
JP7539836B2 JP2020554520A JP2020554520A JP7539836B2 JP 7539836 B2 JP7539836 B2 JP 7539836B2 JP 2020554520 A JP2020554520 A JP 2020554520A JP 2020554520 A JP2020554520 A JP 2020554520A JP 7539836 B2 JP7539836 B2 JP 7539836B2
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ウェン，リンドン
リー，グロリア・ワイ
トナー，メフメット
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ザ ジェネラル ホスピタル コーポレイション
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61D—VETERINARY INSTRUMENTS, IMPLEMENTS, TOOLS, OR METHODS
    • A61D19/00—Instruments or methods for reproduction or fertilisation
    • A61D19/02—Instruments or methods for reproduction or fertilisation for artificial insemination
    • A61D19/027—Devices for injecting semen into animals, e.g. syringes, guns, probes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61D—VETERINARY INSTRUMENTS, IMPLEMENTS, TOOLS, OR METHODS
    • A61D19/00—Instruments or methods for reproduction or fertilisation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61D—VETERINARY INSTRUMENTS, IMPLEMENTS, TOOLS, OR METHODS
    • A61D19/00—Instruments or methods for reproduction or fertilisation
    • A61D19/02—Instruments or methods for reproduction or fertilisation for artificial insemination
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61D—VETERINARY INSTRUMENTS, IMPLEMENTS, TOOLS, OR METHODS
    • A61D19/00—Instruments or methods for reproduction or fertilisation
    • A61D19/04—Instruments or methods for reproduction or fertilisation for embryo transplantation
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M21/00—Bioreactors or fermenters specially adapted for specific uses
    • C12M21/06—Bioreactors or fermenters specially adapted for specific uses for in vitro fertilization
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/02—Form or structure of the vessel
    • C12M23/16—Microfluidic devices; Capillary tubes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M3/00—Tissue, human, animal or plant cell, or virus culture apparatus
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502746—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by the means for controlling flow resistance, e.g. flow controllers, baffles or throttle valves

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Biomedical Technology (AREA)
  • Reproductive Health (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Sustainable Development (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Clinical Laboratory Science (AREA)
  • Transplantation (AREA)
  • Dispersion Chemistry (AREA)
  • Surgery (AREA)
  • Molecular Biology (AREA)
  • Animal Husbandry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cell Biology (AREA)
  • Virology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
JP2020554520A 2018-04-04 2019-04-04 哺乳類卵母細胞を裸化するためのマイクロ流体システムおよび方法 Active JP7539836B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201862652648P 2018-04-04 2018-04-04
US62/652,648 2018-04-04
US201862732884P 2018-09-18 2018-09-18
US62/732,884 2018-09-18
PCT/US2019/025895 WO2019195620A1 (en) 2018-04-04 2019-04-04 Microfluidic systems and methods to denude mammalian oocytes

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JP2021520785A JP2021520785A (ja) 2021-08-26
JP2021520785A5 JP2021520785A5 (cg-RX-API-DMAC7.html) 2022-02-24
JP7539836B2 true JP7539836B2 (ja) 2024-08-26

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US (1) US12383389B2 (cg-RX-API-DMAC7.html)
EP (1) EP3774050A4 (cg-RX-API-DMAC7.html)
JP (1) JP7539836B2 (cg-RX-API-DMAC7.html)
CN (1) CN112154031B (cg-RX-API-DMAC7.html)
AU (1) AU2019247412B2 (cg-RX-API-DMAC7.html)
CA (1) CA3096048A1 (cg-RX-API-DMAC7.html)
IL (1) IL277771A (cg-RX-API-DMAC7.html)
WO (1) WO2019195620A1 (cg-RX-API-DMAC7.html)

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WO2022010894A1 (en) * 2020-07-06 2022-01-13 Cornell University Methods and devices for automated microfluidic oocyte denudation
US20240026263A1 (en) * 2020-09-30 2024-01-25 John Collins Modeling, monitoring and manufacturing of multi-organ systems for human physiology and pathology
EP4228533A4 (en) * 2020-10-16 2025-09-03 Overture Life Inc MICROFLUIDIC DEVICES AND METHODS FOR CELL DENUDATION
US20250154454A1 (en) * 2021-12-20 2025-05-15 The General Hospital Corporation Microfluidic systems and methods for isolating target entities
WO2025034894A1 (en) * 2023-08-08 2025-02-13 Autoivf, Inc. Devices and methods for isolation of biological entities in suspension

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WO2017055361A1 (en) 2015-09-28 2017-04-06 Marion Vollmer Medical device for the selective separation of a biological sample
WO2017173373A1 (en) 2016-03-31 2017-10-05 Massachusetts Institute Of Technology Flow-through microfluidic methods and devices featuring membrane-perturbing surface interactions for intracellular delivery

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WO2017055361A1 (en) 2015-09-28 2017-04-06 Marion Vollmer Medical device for the selective separation of a biological sample
WO2017173373A1 (en) 2016-03-31 2017-10-05 Massachusetts Institute Of Technology Flow-through microfluidic methods and devices featuring membrane-perturbing surface interactions for intracellular delivery

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Publication number Publication date
CN112154031B (zh) 2023-05-23
CA3096048A1 (en) 2019-10-10
EP3774050A4 (en) 2021-06-30
WO2019195620A1 (en) 2019-10-10
EP3774050A1 (en) 2021-02-17
US20210161635A1 (en) 2021-06-03
AU2019247412B2 (en) 2023-07-06
AU2019247412A1 (en) 2020-10-29
US12383389B2 (en) 2025-08-12
IL277771A (en) 2020-11-30
CN112154031A (zh) 2020-12-29
JP2021520785A (ja) 2021-08-26

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