JP7535519B2 - メチルセルロースを含む徐放性組成物 - Google Patents

メチルセルロースを含む徐放性組成物 Download PDF

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Publication number
JP7535519B2
JP7535519B2 JP2021534753A JP2021534753A JP7535519B2 JP 7535519 B2 JP7535519 B2 JP 7535519B2 JP 2021534753 A JP2021534753 A JP 2021534753A JP 2021534753 A JP2021534753 A JP 2021534753A JP 7535519 B2 JP7535519 B2 JP 7535519B2
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methylcellulose
anhydroglucose units
active ingredient
composition
hydrogen atoms
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Japanese (ja)
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JP2022515067A5 (https=
JP2022515067A (ja
Inventor
ピーターマン、オリバー
Original Assignee
ニュートリション アンド バイオサイエンシズ ユーエスエー １，リミティド ライアビリティ カンパニー
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38—Cellulose; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0065—Forms with gastric retention, e.g. floating on gastric juice, adhering to gastric mucosa, expanding to prevent passage through the pylorus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4808—Preparations in capsules, e.g. of gelatin, of chocolate characterised by the form of the capsule or the structure of the filling; Capsules containing small tablets; Capsules with outer layer for immediate drug release
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4816—Wall or shell material
    • A61K9/4825—Proteins, e.g. gelatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4833—Encapsulating processes; Filling of capsules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4866—Organic macromolecular compounds
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B11/00—Preparation of cellulose ethers
    • C08B11/02—Alkyl or cycloalkyl ethers
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L1/00—Compositions of cellulose, modified cellulose or cellulose derivatives
    • C08L1/08—Cellulose derivatives
    • C08L1/26—Cellulose ethers
    • C08L1/28—Alkyl ethers

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • Materials Engineering (AREA)
  • Inorganic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
JP2021534753A 2018-12-18 2019-12-17 メチルセルロースを含む徐放性組成物 Active JP7535519B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP18213440 2018-12-18
EP18213440.3 2018-12-18
PCT/US2019/066704 WO2020131780A1 (en) 2018-12-18 2019-12-17 A sustained release composition comprising a methylcellulose

Publications (3)

Publication Number Publication Date
JP2022515067A JP2022515067A (ja) 2022-02-17
JP2022515067A5 JP2022515067A5 (https=) 2024-04-16
JP7535519B2 true JP7535519B2 (ja) 2024-08-16

Family

ID=64744643

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2021534753A Active JP7535519B2 (ja) 2018-12-18 2019-12-17 メチルセルロースを含む徐放性組成物

Country Status (4)

Country Link
US (2) US20220031623A1 (https=)
EP (1) EP3897729B8 (https=)
JP (1) JP7535519B2 (https=)
WO (1) WO2020131780A1 (https=)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2025525831A (ja) 2022-08-02 2025-08-07 ニュートリション アンド バイオサイエンシズ ユーエスエー １，リミティド ライアビリティ カンパニー アルギネートをベースとする放出調節組成物

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2002541270A (ja) 1999-04-01 2002-12-03 ザ ダウ ケミカル カンパニー 向上したゲル強度のメチルセルロース
JP2014530856A (ja) 2011-10-19 2014-11-20 ダウ グローバル テクノロジーズ エルエルシー 満腹を誘導する方法および組成物
JP2014530857A (ja) 2011-10-19 2014-11-20 ダウ グローバル テクノロジーズ エルエルシー 満腹を誘導する方法および組成物
WO2017182851A1 (en) 2014-05-01 2017-10-26 Sun Pharmaceutical Industries Limited Extended release suspension compositions
JP2017536404A (ja) 2014-12-05 2017-12-07 サン ファーマシューティカル インダストリーズ リミテッドＳｕｎ Ｐｈａｒｍａｃｅｕｔｉｃａｌ Ｉｎｄｕｓｔｒｉｅｓ Ｌｔｄ． 胃保持性の徐放性懸濁組成物

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2917104A1 (de) 1979-04-27 1980-11-06 Hoechst Ag Verfahren zur viskositaetserniedrigung von celluloseethern durch ozon und seine verwendung
JPS6225101A (ja) 1985-07-24 1987-02-03 Shin Etsu Chem Co Ltd 低重合度セルロ−スエ−テルの製造方法
US4734285A (en) 1985-10-28 1988-03-29 The Dow Chemical Company Sustained release compositions
US6261218B1 (en) 1998-12-01 2001-07-17 The Dow Chemical Company Process and apparatus for making low molecular weight cellulose ethers
RU2325152C2 (ru) * 2001-07-04 2008-05-27 Сан Фармасьютикл Индастриз Лимитид Удерживаемая в желудке система регулируемой доставки лекарственного средства
DE10141680B4 (de) 2001-08-25 2004-02-26 Clariant Gmbh Verfahren zur Herstellung niederviskoser Celluloseether durch sauer-oxidativen Abbau von gemahlenen und getrockneten Celluloseethern
WO2014168914A1 (en) 2013-04-12 2014-10-16 Dow Global Technologies Llc Water-soluble polysaccharides of improved palatability
KR20140133724A (ko) 2013-05-10 2014-11-20 한양대학교 산학협력단 저분자 메틸셀룰로오스 기반의 비경구 약물 전달 시스템
WO2015009796A1 (en) * 2013-07-17 2015-01-22 Dow Global Technologies Llc Composition for application to a mucosa comprising a methylcellulose
EP3216807B2 (en) 2016-03-09 2022-05-18 Shin-Etsu Chemical Co., Ltd. Coating composition containing methyl cellulose, method for producing the same, and solid preparation

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2002541270A (ja) 1999-04-01 2002-12-03 ザ ダウ ケミカル カンパニー 向上したゲル強度のメチルセルロース
JP2014530856A (ja) 2011-10-19 2014-11-20 ダウ グローバル テクノロジーズ エルエルシー 満腹を誘導する方法および組成物
JP2014530857A (ja) 2011-10-19 2014-11-20 ダウ グローバル テクノロジーズ エルエルシー 満腹を誘導する方法および組成物
WO2017182851A1 (en) 2014-05-01 2017-10-26 Sun Pharmaceutical Industries Limited Extended release suspension compositions
JP2017536404A (ja) 2014-12-05 2017-12-07 サン ファーマシューティカル インダストリーズ リミテッドＳｕｎ Ｐｈａｒｍａｃｅｕｔｉｃａｌ Ｉｎｄｕｓｔｒｉｅｓ Ｌｔｄ． 胃保持性の徐放性懸濁組成物

Also Published As

Publication number Publication date
EP3897729A1 (en) 2021-10-27
US20250248943A1 (en) 2025-08-07
EP3897729B8 (en) 2025-01-22
JP2022515067A (ja) 2022-02-17
US20220031623A1 (en) 2022-02-03
WO2020131780A1 (en) 2020-06-25
EP3897729B1 (en) 2024-03-13

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