JP7514763B2 - 亜鉛イオノフォアおよびその使用 - Google Patents

亜鉛イオノフォアおよびその使用 Download PDF

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Publication number
JP7514763B2
JP7514763B2 JP2020541834A JP2020541834A JP7514763B2 JP 7514763 B2 JP7514763 B2 JP 7514763B2 JP 2020541834 A JP2020541834 A JP 2020541834A JP 2020541834 A JP2020541834 A JP 2020541834A JP 7514763 B2 JP7514763 B2 JP 7514763B2
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Prior art keywords
zinc
antibiotic
pharma
optionally substituted
ceutically acceptable
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English (en)
Japanese (ja)
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JP2020536966A5 (enExample
JP2020536966A (ja
Inventor
マーク ウォーカー
クリストファー マクデビット
イツスタイン マーク フォン
アラステア マキュアン
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Griffith University
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Griffith University
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Priority claimed from AU2017904135A external-priority patent/AU2017904135A0/en
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Priority to JP2024040061A priority Critical patent/JP2024073569A/ja
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/473—Quinolines; Isoquinolines ortho- or peri-condensed with carbocyclic ring systems, e.g. acridines, phenanthridines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/555—Heterocyclic compounds containing heavy metals, e.g. hemin, hematin, melarsoprol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A61K33/30—Zinc; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Oncology (AREA)
  • Organic Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Inorganic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2020541834A 2017-10-13 2018-10-12 亜鉛イオノフォアおよびその使用 Active JP7514763B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2024040061A JP2024073569A (ja) 2017-10-13 2024-03-14 亜鉛イオノフォアおよびその使用

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
AU2017904135A AU2017904135A0 (en) 2017-10-13 Compositions and their uses
AU2017904135 2017-10-13
PCT/AU2018/051116 WO2019071325A1 (en) 2017-10-13 2018-10-12 ZINC IONOPHORES AND USES THEREOF

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2024040061A Division JP2024073569A (ja) 2017-10-13 2024-03-14 亜鉛イオノフォアおよびその使用

Publications (3)

Publication Number Publication Date
JP2020536966A JP2020536966A (ja) 2020-12-17
JP2020536966A5 JP2020536966A5 (enExample) 2021-11-18
JP7514763B2 true JP7514763B2 (ja) 2024-07-11

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Family Applications (2)

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JP2020541834A Active JP7514763B2 (ja) 2017-10-13 2018-10-12 亜鉛イオノフォアおよびその使用
JP2024040061A Withdrawn JP2024073569A (ja) 2017-10-13 2024-03-14 亜鉛イオノフォアおよびその使用

Family Applications After (1)

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JP2024040061A Withdrawn JP2024073569A (ja) 2017-10-13 2024-03-14 亜鉛イオノフォアおよびその使用

Country Status (6)

Country Link
US (1) US20200261440A1 (enExample)
EP (1) EP3694515A4 (enExample)
JP (2) JP7514763B2 (enExample)
CN (1) CN111787921A (enExample)
AU (1) AU2018348796B2 (enExample)
WO (1) WO2019071325A1 (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR3114742A1 (fr) * 2020-10-04 2022-04-08 Bruno Eto Composition pharmaceutique ou diététique pour bloquer la synthèse des peptides par les ribosomes.
TW202334089A (zh) 2021-11-02 2023-09-01 美商夫雷爾醫療公司 Ｐｐａｒｇ反向激動劑及其用途
CN116726145A (zh) * 2022-03-04 2023-09-12 海南普利制药股份有限公司 一种稳定的酯肽类药物组合物
EP4565234A1 (en) * 2022-08-01 2025-06-11 Griffith University Antibacterial compound pbt2
CN120695002A (zh) * 2025-06-24 2025-09-26 南方医科大学南方医院 Pbt2在制备抗白念珠菌生物膜药物中的应用

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2006504646A (ja) 2002-07-16 2006-02-09 プラナ バイオテクノロジー リミティッド ８−ヒドロキシキノリン誘導体
WO2009140215A2 (en) 2008-05-11 2009-11-19 Geraghty, Erin Method for treating drug-resistant bacterial and other infections with clioquinol, phanquinone, and related compounds
JP2016538244A (ja) 2013-10-04 2016-12-08 ウニヴァーシテテット イ オスロ 化合物
WO2017053696A2 (en) 2015-09-24 2017-03-30 University Of Florida Research Foundation, Incorporated Halogenated quinoline derivatives as antimicrobial agents

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5696083A (en) * 1992-11-10 1997-12-09 Olin Corporation Personal care composition containing pyrithione and polymyxin
HUE030264T2 (en) * 2005-06-28 2017-04-28 Janssen Pharmaceutica Nv Quinoline derivatives as antibacterial agents
US20110189260A1 (en) * 2008-05-30 2011-08-04 University Of Cincinnati Use of zinc chelators to inhibit biofilm formation
WO2014172435A1 (en) * 2013-04-16 2014-10-23 University Of Cincinnati Antimicrobial compositions of aminoglycosidic antibiotics and zinc ion chelators
CN107896480A (zh) * 2015-06-23 2018-04-10 詹森药业有限公司 食品准许的抗微生物剂和吡硫锌的组合

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2006504646A (ja) 2002-07-16 2006-02-09 プラナ バイオテクノロジー リミティッド ８−ヒドロキシキノリン誘導体
WO2009140215A2 (en) 2008-05-11 2009-11-19 Geraghty, Erin Method for treating drug-resistant bacterial and other infections with clioquinol, phanquinone, and related compounds
JP2016538244A (ja) 2013-10-04 2016-12-08 ウニヴァーシテテット イ オスロ 化合物
WO2017053696A2 (en) 2015-09-24 2017-03-30 University Of Florida Research Foundation, Incorporated Halogenated quinoline derivatives as antimicrobial agents

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
Antimicrobial Agents and Chemotherapy，2015年，Vol.59, No.9，p.5851-5853
European Journal of Medicinal Chemistry，2016年，Vol.120，p.252-274
Microibiology Resource Announcements，2018年，Vol.7, No.4, e00886-18，p.1-2

Also Published As

Publication number Publication date
JP2020536966A (ja) 2020-12-17
AU2018348796B2 (en) 2024-09-26
AU2018348796A1 (en) 2020-05-07
JP2024073569A (ja) 2024-05-29
EP3694515A1 (en) 2020-08-19
US20200261440A1 (en) 2020-08-20
EP3694515A4 (en) 2021-04-21
CN111787921A (zh) 2020-10-16
WO2019071325A1 (en) 2019-04-18

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