JP7478162B2 - マイクロニードルパッチのためのアプリケータ - Google Patents
マイクロニードルパッチのためのアプリケータ Download PDFInfo
- Publication number
- JP7478162B2 JP7478162B2 JP2021549343A JP2021549343A JP7478162B2 JP 7478162 B2 JP7478162 B2 JP 7478162B2 JP 2021549343 A JP2021549343 A JP 2021549343A JP 2021549343 A JP2021549343 A JP 2021549343A JP 7478162 B2 JP7478162 B2 JP 7478162B2
- Authority
- JP
- Japan
- Prior art keywords
- applicator
- handle portion
- microneedle patch
- pressing
- pressing body
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 239000013039 cover film Substances 0.000 claims description 29
- 238000000926 separation method Methods 0.000 claims description 16
- 230000000007 visual effect Effects 0.000 claims description 4
- 210000003491 skin Anatomy 0.000 description 23
- 230000006835 compression Effects 0.000 description 11
- 238000007906 compression Methods 0.000 description 11
- 238000004146 energy storage Methods 0.000 description 6
- 230000007246 mechanism Effects 0.000 description 6
- 239000007787 solid Substances 0.000 description 6
- 230000007704 transition Effects 0.000 description 6
- 238000005096 rolling process Methods 0.000 description 4
- 230000004888 barrier function Effects 0.000 description 2
- 230000008878 coupling Effects 0.000 description 2
- 238000010168 coupling process Methods 0.000 description 2
- 238000005859 coupling reaction Methods 0.000 description 2
- 230000036512 infertility Effects 0.000 description 2
- 230000009471 action Effects 0.000 description 1
- 239000013543 active substance Substances 0.000 description 1
- 230000001154 acute effect Effects 0.000 description 1
- 239000000853 adhesive Substances 0.000 description 1
- 230000001070 adhesive effect Effects 0.000 description 1
- 239000003086 colorant Substances 0.000 description 1
- 230000007423 decrease Effects 0.000 description 1
- 230000003111 delayed effect Effects 0.000 description 1
- 230000001419 dependent effect Effects 0.000 description 1
- 230000037431 insertion Effects 0.000 description 1
- 238000003780 insertion Methods 0.000 description 1
- 230000009467 reduction Effects 0.000 description 1
- 210000000434 stratum corneum Anatomy 0.000 description 1
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
- A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A61K9/0021—Intradermal administration, e.g. through microneedle arrays, needleless injectors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
- A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
- A61M2037/0023—Drug applicators using microneedles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
- A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
- A61M2037/0046—Solid microneedles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
- A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
- A61M2037/0061—Methods for using microneedles
Landscapes
- Health & Medical Sciences (AREA)
- Dermatology (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Hematology (AREA)
- Anesthesiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Biomedical Technology (AREA)
- Medical Informatics (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Media Introduction/Drainage Providing Device (AREA)
Description
Claims (9)
- ハンドル部分、及び前記ハンドル部分に連結されている、マイクロニードルパッチのための押圧体を備えているアプリケータであって、
前記押圧体は、外部の操作力及び内部の復元装置によって少なくとも未使用姿勢と使用姿勢との間で前記ハンドル部分に対してピボットジョイントで移動すべく取り付けられており、
前記押圧体は、前記ピボットジョイントから間隔を空けて配置されている押圧面を有しており、
前記未使用姿勢では、前記押圧体は外部の操作力によって負荷がかけられておらず、前記復元装置の内部エネルギーが最も低く、
前記押圧体は、前記押圧面に作用する外部の操作力によって、前記ハンドル部分に対して前記使用姿勢に向かって移動可能であり、前記復元装置の内部エネルギーが増加する、アプリケータ。 - 固定要素が、前記未使用姿勢での移動範囲を制限する、請求項1に記載のアプリケータ。
- 前記押圧体又は前記押圧体を含む押圧体群が前記ハンドル部分上に又は前記ハンドル部分内に取り付けられている、請求項1に記載のアプリケータ。
- 前記復元装置は、負荷に応じた視覚指標、触覚指標又は音響指標を有している、請求項1に記載のアプリケータ。
- 前記押圧面は連続して湾曲した表面であり、前記表面の最小半径の湾曲中心線の少なくとも1つの半径が前記ハンドル部分の長手方向に垂直であり、少なくとも前記使用姿勢で前記ハンドル部分の長手軸芯に対して斜めである、請求項1に記載のアプリケータ。
- 請求項1に係るアプリケータと、複数のマイクロニードルを有するマイクロニードルパッチとを備えており、
前記押圧面の最小半径は、円定数πと前記マイクロニードルパッチの長手方向のマイクロニードルの後端部の長さとの積の少なくとも1.5 倍である、ユニット。 - 前記マイクロニードルパッチはカバーフィルムを少なくとも部分的に保持しており、前記アプリケータは、くさび状の分離縁部及び前記カバーフィルムを偏移させるための隣接する案内面を有している、請求項6に記載のユニット。
- 前記分離縁部は前記押圧体に形成されている、請求項7に記載のユニット。
- 案内要素が前記押圧体に配置されており、前記案内要素は、少なくとも前記マイクロニードルパッチのオーバーパッチ及び前記カバーフィルムと係合する、請求項8に記載のユニット。
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE102019001251.8A DE102019001251A1 (de) | 2019-02-21 | 2019-02-21 | Applikator für Mikronadelpflaster |
DE102019001251.8 | 2019-02-21 | ||
PCT/EP2020/054362 WO2020169667A1 (de) | 2019-02-21 | 2020-02-19 | Applikator für mikronadelpflaster |
Publications (2)
Publication Number | Publication Date |
---|---|
JP2022546654A JP2022546654A (ja) | 2022-11-07 |
JP7478162B2 true JP7478162B2 (ja) | 2024-05-02 |
Family
ID=69631607
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2021549343A Active JP7478162B2 (ja) | 2019-02-21 | 2020-02-19 | マイクロニードルパッチのためのアプリケータ |
Country Status (9)
Country | Link |
---|---|
US (1) | US20220126079A1 (ja) |
EP (1) | EP3927412B1 (ja) |
JP (1) | JP7478162B2 (ja) |
CN (1) | CN113474035B (ja) |
BR (1) | BR112021016246A2 (ja) |
CA (1) | CA3129127A1 (ja) |
DE (1) | DE102019001251A1 (ja) |
ES (1) | ES2966126T3 (ja) |
WO (1) | WO2020169667A1 (ja) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE102021130950A1 (de) * | 2021-11-25 | 2023-05-25 | Lts Lohmann Therapie-Systeme Ag. | Applikationshilfe |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2007002521A2 (en) | 2005-06-27 | 2007-01-04 | 3M Innovative Properties Company | Microneedle array applicator device |
US20180177991A1 (en) | 2016-12-26 | 2018-06-28 | Industry-Academic Cooperation Foundation, Yonsei University | Microneedle applicator |
WO2018116986A1 (ja) | 2016-12-20 | 2018-06-28 | 久光製薬株式会社 | アプリケータ |
WO2018116990A1 (ja) | 2016-12-20 | 2018-06-28 | 久光製薬株式会社 | アプリケータ |
Family Cites Families (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6589202B1 (en) * | 2000-06-29 | 2003-07-08 | Becton Dickinson And Company | Method and apparatus for transdermally sampling or administering a substance to a patient |
US7658728B2 (en) * | 2006-01-10 | 2010-02-09 | Yuzhakov Vadim V | Microneedle array, patch, and applicator for transdermal drug delivery |
US8821446B2 (en) * | 2007-01-22 | 2014-09-02 | Corium International, Inc. | Applicators for microneedles |
WO2013015136A1 (ja) * | 2011-07-27 | 2013-01-31 | 久光製薬株式会社 | アプリケータ |
JP5921557B2 (ja) * | 2011-09-16 | 2016-05-24 | 久光製薬株式会社 | アプリケータ |
JP6182137B2 (ja) * | 2012-06-12 | 2017-08-16 | 久光製薬株式会社 | マイクロニードル・シート |
CA2903748C (en) * | 2013-03-12 | 2021-11-02 | Corium International, Inc. | Microprojection applicators |
JP2016517707A (ja) * | 2013-03-22 | 2016-06-20 | スリーエム イノベイティブ プロパティズ カンパニー | カウンタ組立体を備えているマイクロニードルアプリケータ |
JP6272333B2 (ja) * | 2013-09-06 | 2018-01-31 | 久光製薬株式会社 | マイクロニードル・シート |
US10828478B2 (en) * | 2014-04-24 | 2020-11-10 | Georgia Tech Research Corporation | Microneedles and methods of manufacture thereof |
JP6398293B2 (ja) * | 2014-04-25 | 2018-10-03 | 凸版印刷株式会社 | 針状体デバイス |
US11116953B2 (en) * | 2015-02-13 | 2021-09-14 | Medrx Co., Ltd. | Microneedle applicator and microneedle patch application device |
EP3421074B1 (en) * | 2016-02-24 | 2024-03-20 | Hisamitsu Pharmaceutical Co., Inc. | Applicator |
KR102354760B1 (ko) * | 2017-11-30 | 2022-01-21 | 히사미쓰 세이야꾸 가부시키가이샤 | 어플리케이터, 카트리지 및 어플리케이션·키트 |
-
2019
- 2019-02-21 DE DE102019001251.8A patent/DE102019001251A1/de active Pending
-
2020
- 2020-02-19 WO PCT/EP2020/054362 patent/WO2020169667A1/de unknown
- 2020-02-19 EP EP20706234.0A patent/EP3927412B1/de active Active
- 2020-02-19 US US17/432,581 patent/US20220126079A1/en active Pending
- 2020-02-19 JP JP2021549343A patent/JP7478162B2/ja active Active
- 2020-02-19 ES ES20706234T patent/ES2966126T3/es active Active
- 2020-02-19 CN CN202080014414.3A patent/CN113474035B/zh active Active
- 2020-02-19 CA CA3129127A patent/CA3129127A1/en active Pending
- 2020-02-19 BR BR112021016246-1A patent/BR112021016246A2/pt unknown
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2007002521A2 (en) | 2005-06-27 | 2007-01-04 | 3M Innovative Properties Company | Microneedle array applicator device |
WO2018116986A1 (ja) | 2016-12-20 | 2018-06-28 | 久光製薬株式会社 | アプリケータ |
WO2018116990A1 (ja) | 2016-12-20 | 2018-06-28 | 久光製薬株式会社 | アプリケータ |
US20180177991A1 (en) | 2016-12-26 | 2018-06-28 | Industry-Academic Cooperation Foundation, Yonsei University | Microneedle applicator |
Also Published As
Publication number | Publication date |
---|---|
EP3927412A1 (de) | 2021-12-29 |
US20220126079A1 (en) | 2022-04-28 |
EP3927412C0 (de) | 2023-09-13 |
EP3927412B1 (de) | 2023-09-13 |
BR112021016246A2 (pt) | 2021-10-13 |
CN113474035B (zh) | 2023-06-20 |
CN113474035A (zh) | 2021-10-01 |
DE102019001251A1 (de) | 2020-08-27 |
ES2966126T3 (es) | 2024-04-18 |
JP2022546654A (ja) | 2022-11-07 |
WO2020169667A1 (de) | 2020-08-27 |
CA3129127A1 (en) | 2020-08-27 |
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