JP7476317B2 - 非侵襲物質分析装置 - Google Patents

非侵襲物質分析装置 Download PDF

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JP7476317B2
JP7476317B2 JP2022540426A JP2022540426A JP7476317B2 JP 7476317 B2 JP7476317 B2 JP 7476317B2 JP 2022540426 A JP2022540426 A JP 2022540426A JP 2022540426 A JP2022540426 A JP 2022540426A JP 7476317 B2 JP7476317 B2 JP 7476317B2
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waveguide
light
ring resonator
sample
type ring
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JPWO2023157163A1 (https=
JPWO2023157163A5 (https=
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周作 林
浩一 秋山
祐樹 津田
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Mitsubishi Electric Corp
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Mitsubishi Electric Corp
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483—Physical analysis of biological material
    • G01N33/487—Physical analysis of biological material of liquid biological material
    • G01N33/49—Blood
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
    • A61B5/14532—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue for measuring glucose, e.g. by tissue impedance measurement
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
    • A61B5/14546—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue for measuring analytes not otherwise provided for, e.g. ions, cytochromes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
    • A61B5/1455—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue using optical sensors, e.g. spectral photometrical oximeters
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/171—Systems in which incident light is modified in accordance with the properties of the material investigated with calorimetric detection, e.g. with thermal lens detection
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/1717—Systems in which incident light is modified in accordance with the properties of the material investigated with a modulation of one or more physical properties of the sample during the optical investigation, e.g. electro-reflectance
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/25—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
    • G01N21/31—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry
    • G01N21/35—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry using infrared light
    • G01N21/3577—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry using infrared light for analysing liquids, e.g. polluted water
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/41—Refractivity; Phase-affecting properties, e.g. optical path length
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/1717—Systems in which incident light is modified in accordance with the properties of the material investigated with a modulation of one or more physical properties of the sample during the optical investigation, e.g. electro-reflectance
    • G01N2021/1731—Temperature modulation
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/25—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
    • G01N21/31—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry
    • G01N21/39—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry using tunable lasers
    • G01N2021/396—Type of laser source
    • G01N2021/399—Diode laser
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/41—Refractivity; Phase-affecting properties, e.g. optical path length
    • G01N21/45—Refractivity; Phase-affecting properties, e.g. optical path length using interferometric methods; using Schlieren methods
    • G01N2021/458—Refractivity; Phase-affecting properties, e.g. optical path length using interferometric methods; using Schlieren methods using interferential sensor, e.g. sensor fibre, possibly on optical waveguide
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
    • G01N21/77—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
    • G01N21/7703—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator using reagent-clad optical fibres or optical waveguides
    • G01N21/7746—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator using reagent-clad optical fibres or optical waveguides the waveguide coupled to a cavity resonator
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2201/00—Features of devices classified in G01N21/00
    • G01N2201/08—Optical fibres; light guides
    • G01N2201/0873—Using optically integrated constructions
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2201/00—Features of devices classified in G01N21/00
    • G01N2201/08—Optical fibres; light guides
    • G01N2201/088—Using a sensor fibre

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Pathology (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Optics & Photonics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Surgery (AREA)
  • Medical Informatics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Ecology (AREA)
  • Urology & Nephrology (AREA)
  • Emergency Medicine (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Investigating Or Analyzing Materials Using Thermal Means (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
JP2022540426A 2022-02-17 2022-02-17 非侵襲物質分析装置 Active JP7476317B2 (ja)

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Application Number Priority Date Filing Date Title
PCT/JP2022/006341 WO2023157163A1 (ja) 2022-02-17 2022-02-17 非侵襲物質分析装置

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JPWO2023157163A1 JPWO2023157163A1 (https=) 2023-08-24
JPWO2023157163A5 JPWO2023157163A5 (https=) 2024-01-23
JP7476317B2 true JP7476317B2 (ja) 2024-04-30

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US (1) US12607621B2 (https=)
JP (1) JP7476317B2 (https=)
CN (1) CN118679373A (https=)
DE (1) DE112022006679T5 (https=)
WO (1) WO2023157163A1 (https=)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US12292400B2 (en) * 2022-02-17 2025-05-06 Mitsubishi Electric Corporation Non-invasive substance analysis apparatus
US12436413B2 (en) * 2022-03-31 2025-10-07 Intel Corporation Undercut design with a bonded base cover for friendly assembly and effective thermal tuning of micro-ring resonator (MRR) in open cavity photonic integrated chips (OCPIC)

Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2003527625A (ja) 1999-10-14 2003-09-16 ランブダ・クロツシング・リミテツド データ通信のための集積光学デバイス
JP2004325128A (ja) 2003-04-22 2004-11-18 Hitachi Medical Corp 光計測装置
JP2012108095A (ja) 2010-08-03 2012-06-07 Fuji Electric Co Ltd 多成分用レーザ式ガス分析計
US20140321502A1 (en) 2013-06-11 2014-10-30 National Institute Of Standards And Technology Optical temperature sensor and use of same
JP2015502539A (ja) 2011-11-21 2015-01-22 カリフォルニア インスティチュート オブ テクノロジー 光共振診断装置およびその使用方法
US20180330946A1 (en) 2017-05-12 2018-11-15 Ohio State Innovation Foundation Devices, systems, and methods for light emission and detection using amorphous silicon
JP6786027B1 (ja) 2020-03-04 2020-11-18 三菱電機株式会社 生体成分測定装置
JP2022506275A (ja) 2018-11-08 2022-01-17 ディアモンテク、アクチェンゲゼルシャフト 物質を分析するための装置および方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL132385A0 (en) 1999-10-14 2001-03-19 Lambda Crossing Ltd An integrated optical device for data communications
DE102014108424B3 (de) 2014-06-16 2015-06-11 Johann Wolfgang Goethe-Universität Nicht-invasive Stoffanalyse
US11141087B2 (en) * 2019-05-17 2021-10-12 Arun Ananth Aiyer Optical device for non-invasive continuous monitoring of blood glucose level and HbA1c concentration
US11624615B2 (en) * 2020-10-05 2023-04-11 Anello Photonics, Inc. Ring waveguide based integrated photonics optical gyroscope with balanced detection scheme

Patent Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2003527625A (ja) 1999-10-14 2003-09-16 ランブダ・クロツシング・リミテツド データ通信のための集積光学デバイス
JP2004325128A (ja) 2003-04-22 2004-11-18 Hitachi Medical Corp 光計測装置
JP2012108095A (ja) 2010-08-03 2012-06-07 Fuji Electric Co Ltd 多成分用レーザ式ガス分析計
JP2015502539A (ja) 2011-11-21 2015-01-22 カリフォルニア インスティチュート オブ テクノロジー 光共振診断装置およびその使用方法
US20140321502A1 (en) 2013-06-11 2014-10-30 National Institute Of Standards And Technology Optical temperature sensor and use of same
US20180330946A1 (en) 2017-05-12 2018-11-15 Ohio State Innovation Foundation Devices, systems, and methods for light emission and detection using amorphous silicon
JP2022506275A (ja) 2018-11-08 2022-01-17 ディアモンテク、アクチェンゲゼルシャフト 物質を分析するための装置および方法
JP6786027B1 (ja) 2020-03-04 2020-11-18 三菱電機株式会社 生体成分測定装置

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
ＳＩＮＧＨＡ ｅｔ ａｌ．、Ｏｎ－ｃｈｉｐ Ｐｈｏｔｏｎｉｃ Ｔｅｍｐｅｒａｔｕｒｅ Ｓｅｎｓｏｒ Ｕｓｉｎｇ Ｍｉｃｒｏ Ｒｉｎｇ Ｒｅｓｏｎａｔｏｒ、２０１８ Ｆｉｆｔｅｅｎｔｈ Ｉｎｔｅｒｎａｔｉｏｎａｌ Ｃｏｎｆｅｒｅｎｃｅ ｏｎ Ｗｉｒｅｌｅｓｓ ａｎｄ Ｏｐｔｉｃａｌ Ｃｏｍｍｕｎｉｃａｔｉｏｎｓ Ｎｅｔｗｏｒｋｓ（ＷＯＣＮ）、その他、２０１８．発行

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DE112022006679T5 (de) 2024-12-24
US20250137992A1 (en) 2025-05-01
JPWO2023157163A1 (https=) 2023-08-24
US12607621B2 (en) 2026-04-21
WO2023157163A1 (ja) 2023-08-24
CN118679373A (zh) 2024-09-20

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