JP7466308B2 - Usp10バイオマーカーおよびモジュレーターを用いたamlの同定、評価、予防および処置のための組成物および方法 - Google Patents
Usp10バイオマーカーおよびモジュレーターを用いたamlの同定、評価、予防および処置のための組成物および方法 Download PDFInfo
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- JP7466308B2 JP7466308B2 JP2019537032A JP2019537032A JP7466308B2 JP 7466308 B2 JP7466308 B2 JP 7466308B2 JP 2019537032 A JP2019537032 A JP 2019537032A JP 2019537032 A JP2019537032 A JP 2019537032A JP 7466308 B2 JP7466308 B2 JP 7466308B2
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- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
- C07K16/3061—Blood cells
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- A01K67/00—Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
- A01K67/027—New or modified breeds of vertebrates
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- C12Q1/025—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
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- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
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- C12Q1/6844—Nucleic acid amplification reactions
- C12Q1/6851—Quantitative amplification
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- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
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- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
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- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57407—Specifically defined cancers
- G01N33/57426—Specifically defined cancers leukemia
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- A—HUMAN NECESSITIES
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- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2267/00—Animals characterised by purpose
- A01K2267/03—Animal model, e.g. for test or diseases
- A01K2267/0331—Animal model for proliferative diseases
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
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- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
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- C12Q2600/00—Oligonucleotides characterized by their use
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis
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- Proteomics, Peptides & Aminoacids (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
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- Biomedical Technology (AREA)
- General Engineering & Computer Science (AREA)
- Cell Biology (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
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Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2022094297A JP2022116353A (ja) | 2016-09-20 | 2022-06-10 | Usp10バイオマーカーおよびモジュレーターを用いたamlの同定、評価、予防および処置のための組成物および方法 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662397100P | 2016-09-20 | 2016-09-20 | |
| US62/397,100 | 2016-09-20 | ||
| PCT/US2017/052506 WO2018057618A1 (en) | 2016-09-20 | 2017-09-20 | Compositions and methods for identification, assessment, prevention, and treatment of aml using usp10 biomarkers and modulators |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022094297A Division JP2022116353A (ja) | 2016-09-20 | 2022-06-10 | Usp10バイオマーカーおよびモジュレーターを用いたamlの同定、評価、予防および処置のための組成物および方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2019534321A JP2019534321A (ja) | 2019-11-28 |
| JP2019534321A5 JP2019534321A5 (enExample) | 2020-08-27 |
| JP7466308B2 true JP7466308B2 (ja) | 2024-04-12 |
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Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019537032A Active JP7466308B2 (ja) | 2016-09-20 | 2017-09-20 | Usp10バイオマーカーおよびモジュレーターを用いたamlの同定、評価、予防および処置のための組成物および方法 |
| JP2022094297A Pending JP2022116353A (ja) | 2016-09-20 | 2022-06-10 | Usp10バイオマーカーおよびモジュレーターを用いたamlの同定、評価、予防および処置のための組成物および方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022094297A Pending JP2022116353A (ja) | 2016-09-20 | 2022-06-10 | Usp10バイオマーカーおよびモジュレーターを用いたamlの同定、評価、予防および処置のための組成物および方法 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US11136409B2 (enExample) |
| EP (1) | EP3515559B1 (enExample) |
| JP (2) | JP7466308B2 (enExample) |
| AU (1) | AU2017332721B2 (enExample) |
| CA (1) | CA3034643A1 (enExample) |
| ES (1) | ES3033182T3 (enExample) |
| WO (1) | WO2018057618A1 (enExample) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB201617758D0 (en) * | 2016-10-20 | 2016-12-07 | Almac Discovery Limited | Pharmaceutical compounds |
| WO2020165315A1 (en) * | 2019-02-14 | 2020-08-20 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Use of usp7 inhibitors for the treatment of acute myeloid leukemia (aml) |
| US20220281886A1 (en) * | 2019-05-22 | 2022-09-08 | Merck Sharp Dohme Corp. | Natriuretic peptide receptor a agonists useful for the treatment of cardiometabolic diseases, kidney disease and diabetes |
| CN117427085A (zh) * | 2020-02-21 | 2024-01-23 | 中国科学院上海药物研究所 | 金诺芬等老药及其组合物在抗单正链rna病毒中的应用 |
| CN115427076B (zh) * | 2020-02-28 | 2025-01-03 | 免疫学有限公司 | 用于治疗冠状病毒感染的人去泛素化酶抑制剂 |
| CN113838206B (zh) * | 2021-09-28 | 2023-05-16 | 南京工业大学 | 一种基于bim的假山瀑布三维设计方法 |
| CN113912595B (zh) * | 2021-10-12 | 2024-03-15 | 中国药科大学 | 一类含有噻唑或噻二唑结构的化合物及其应用 |
| CN114807233B (zh) * | 2022-05-05 | 2023-04-18 | 江苏省人民医院(南京医科大学第一附属医院) | 一种巨噬细胞特异性usp13过表达的重组腺相关病毒及其应用 |
| WO2024097876A1 (en) * | 2022-11-02 | 2024-05-10 | Board Of Regents, The University Of Texas System | Methods relating to optimizing therapy selection for acute myeloid leukemia |
| CN120131695A (zh) * | 2025-03-06 | 2025-06-13 | 浙江大学 | 金诺芬在制备治疗usp6基因重排及异常激活疾病药物中的应用 |
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| US548257A (en) | 1895-10-22 | Hay rake and loader | ||
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| GB8308235D0 (en) | 1983-03-25 | 1983-05-05 | Celltech Ltd | Polypeptides |
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| GB8422238D0 (en) | 1984-09-03 | 1984-10-10 | Neuberger M S | Chimeric proteins |
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| US4902505A (en) | 1986-07-30 | 1990-02-20 | Alkermes | Chimeric peptides for neuropeptide delivery through the blood-brain barrier |
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| Title |
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| Pharmacology&Therapeutics,2015年,Volume147,pp.32-54 |
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| US20190202929A1 (en) | 2019-07-04 |
| AU2017332721A1 (en) | 2019-03-21 |
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| AU2017332721B2 (en) | 2023-11-09 |
| US11136409B2 (en) | 2021-10-05 |
| EP3515559B1 (en) | 2025-05-21 |
| EP3515559A4 (en) | 2020-07-15 |
| ES3033182T3 (en) | 2025-07-31 |
| EP3515559A1 (en) | 2019-07-31 |
| JP2022116353A (ja) | 2022-08-09 |
| CA3034643A1 (en) | 2018-03-29 |
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