JP7458975B2 - Ｃｄ５＋細胞の枯渇のための組成物および方法 - Google Patents

Ｃｄ５＋細胞の枯渇のための組成物および方法 Download PDF

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JP7458975B2
JP7458975B2 JP2020529433A JP2020529433A JP7458975B2 JP 7458975 B2 JP7458975 B2 JP 7458975B2 JP 2020529433 A JP2020529433 A JP 2020529433A JP 2020529433 A JP2020529433 A JP 2020529433A JP 7458975 B2 JP7458975 B2 JP 7458975B2
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optionally substituted
antibody
seq
antigen
cells
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JP2021504412A (ja
JP2021504412A5 (enExample
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ボイタノ アンソニー
クック マイケル
パルチョウデュリー ラーフル
マクドノー ショーン
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Dianthus Therapeutics Inc
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Magenta Therapeutics Inc
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    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
    • A61K47/6801—Drug-antibody or immunoglobulin conjugates defined by the pharmacologically or therapeutically active agent
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    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
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    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
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  • Communicable Diseases (AREA)
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  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
JP2020529433A 2017-11-29 2018-11-29 Ｃｄ５＋細胞の枯渇のための組成物および方法 Active JP7458975B2 (ja)

Priority Applications (1)

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JP2024043371A JP7791923B2 (ja) 2017-11-29 2024-03-19 Ｃｄ５＋細胞の枯渇のための組成物および方法

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US201762592214P 2017-11-29 2017-11-29
US62/592,214 2017-11-29
PCT/US2018/063175 WO2019108863A1 (en) 2017-11-29 2018-11-29 Compositions and methods for the depletion of cd5+ cells

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US (3) US20200276326A1 (enExample)
EP (1) EP3717022A4 (enExample)
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KR (1) KR20200094181A (enExample)
CN (2) CN111670052A (enExample)
AU (1) AU2018374283B2 (enExample)
BR (1) BR112020010662A2 (enExample)
CA (1) CA3082310A1 (enExample)
CO (1) CO2020006865A2 (enExample)
EA (1) EA202090947A1 (enExample)
IL (2) IL316155A (enExample)
MX (1) MX2020004910A (enExample)
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CA3140447A1 (en) * 2019-06-05 2020-12-10 Anthony Boitano T-cell depleting therapies
WO2022089644A1 (zh) * 2020-11-01 2022-05-05 南京驯鹿医疗技术有限公司 靶向cd5的全人源抗体、全人源嵌合抗原受体(car)及其应用
EP4279508A4 (en) * 2021-01-12 2024-12-04 Nanjing Iaso Biotechnology Co., Ltd. Cd5-targeting fully humanized antibody
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EP4572772A1 (en) 2022-08-17 2025-06-25 Capstan Therapeutics, Inc. Conditioning for in vivo immune cell engineering
WO2024249954A1 (en) 2023-05-31 2024-12-05 Capstan Therapeutics, Inc. Lipid nanoparticle formulations and compositions
WO2024258967A1 (en) * 2023-06-13 2024-12-19 Synthis Therapeutics, Inc. Anti-cd5 antibodies and their uses
WO2025076127A1 (en) 2023-10-05 2025-04-10 Capstan Therapeutics, Inc. Constrained ionizable cationic lipids and lipid nanoparticles
WO2025076113A1 (en) 2023-10-05 2025-04-10 Capstan Therapeutics, Inc. Ionizable cationic lipids with conserved spacing and lipid nanoparticles
CN117866096A (zh) * 2023-12-20 2024-04-12 深圳普瑞金生物药业股份有限公司 抗cd5单域抗体及其应用
US20250302763A1 (en) 2024-02-22 2025-10-02 Capstan Therapeutics, Inc. Immune engineering amplification
WO2025217454A2 (en) 2024-04-11 2025-10-16 Capstan Therapeutics, Inc. Ionizable cationic lipids and lipid nanoparticles
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