JP7447011B2 - エフェクターｔ細胞をリプログラムするためのヒストン修飾因子の使用 - Google Patents
エフェクターｔ細胞をリプログラムするためのヒストン修飾因子の使用 Download PDFInfo
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- C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
- C12N2506/11—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from blood or immune system cells
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| PCT/US2019/024693 WO2019191501A1 (en) | 2018-03-28 | 2019-03-28 | Use of histone modifiers to reprogram effector t cells |
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| JP2023210666A Pending JP2024037880A (ja) | 2018-03-28 | 2023-12-14 | エフェクターｔ細胞をリプログラムするためのヒストン修飾因子の使用 |
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| JP2024037880A (ja) * | 2018-03-28 | 2024-03-19 | ボード オブ リージェンツ ザ ユニヴァーシティ オブ テキサス システム | エフェクターｔ細胞をリプログラムするためのヒストン修飾因子の使用 |
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| WO2006065495A2 (en) | 2004-11-24 | 2006-06-22 | Fred Hutchinson Cancer Research Center | Methods of using il-21 for adoptive immunotherapy and identification of tumor antigens |
| KR102069704B1 (ko) * | 2018-05-16 | 2020-01-23 | 고려대학교 산학협력단 | Hdac 억제제를 이용한 사람 유래 자연살해세포의 확장 배양법 |
| WO2020069377A1 (en) * | 2018-09-27 | 2020-04-02 | Arizona Board Of Regents On Behalf Of The University Of Arizona | Methods of using lysine deacetylase (kdac) inhibition to generate antigen specific memory t cell responses for durable immunotherapy |
| US12365871B2 (en) | 2020-04-28 | 2025-07-22 | Lyell Immunopharma, Inc. | Methods for culturing cells |
| JP7785699B2 (ja) * | 2020-05-29 | 2025-12-15 | シャンハイ ジュンセル セラピューティクス カンパニー リミテッド | 腫瘍浸潤リンパ球の種細胞培地及びその使用 |
| GB202008957D0 (en) * | 2020-06-12 | 2020-07-29 | Autolus Ltd | Culture medium |
| CN113502265B (zh) * | 2021-05-25 | 2024-05-28 | 昭泰英基生物医药（香港）有限公司 | 将t细胞重编程为类nk细胞的诱导剂及其应用 |
| WO2023201097A1 (en) * | 2022-04-15 | 2023-10-19 | Turn Biotechnologies, Inc. | Methods and compositions for immune cell rejuvenation and therapies using rejuvenated immune cells |
| US20230355678A1 (en) * | 2022-05-05 | 2023-11-09 | Immatics US, Inc. | Methods for improving t cell efficacy |
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| WO2017219150A1 (en) | 2016-06-24 | 2017-12-28 | Mcmaster University | Adoptive cell transfer and oncolytic virus combination therapy |
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| US6307024B1 (en) | 1999-03-09 | 2001-10-23 | Zymogenetics, Inc. | Cytokine zalpha11 Ligand |
| WO2006065495A2 (en) | 2004-11-24 | 2006-06-22 | Fred Hutchinson Cancer Research Center | Methods of using il-21 for adoptive immunotherapy and identification of tumor antigens |
| RU2763795C2 (ru) * | 2014-04-23 | 2022-01-11 | Джуно Терапьютикс, Инк. | Способы выделения, культивирования и генетической инженерии популяций клеток иммунной системы для адоптивной терапии |
| KR102849343B1 (ko) | 2018-03-07 | 2025-08-25 | 포세이다 테라퓨틱스, 인크. | Cartyrin 조성물 및 사용 방법 |
| KR20200138325A (ko) * | 2018-03-28 | 2020-12-09 | 보드 오브 리전츠, 더 유니버시티 오브 텍사스 시스템 | 이펙터 t 세포를 재프로그래밍하기 위한 히스톤 개질제의 용도 |
| EP3847197A1 (en) * | 2018-09-05 | 2021-07-14 | Poseida Therapeutics, Inc. | Allogeneic cell compositions and methods of use |
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2019
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Patent Citations (1)
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| WO2017219150A1 (en) | 2016-06-24 | 2017-12-28 | Mcmaster University | Adoptive cell transfer and oncolytic virus combination therapy |
Non-Patent Citations (5)
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| BAE, J et al.，Histone deacetylase (HDAC) inhibitor ACY241 enhances anti-tumor activities of antigen-specific central memory cytotoxic T lymphocytes against multiple myeloma and solid tumors，Leukemia，2018年02月，Vol. 32，pp. 1932-1947 |
| HO, LP et al.，The Road to Memory: An Early Rest for the Long Journey，The Journal of Immunology，2013年，Vol. 191, No. 11，pp. 5603-5614 |
| LOSCHINSKI, R et al.，IL-21 modulates memory and exhaustion phenotype of T-cells in a fatty acid oxidation-dependent manner，Oncotarget，2018年02月，Vol. 9, No. 17，pp. 13125-13138 |
| McCAW, TR et al.，Modulation of antitumor immunity with histone deacetylase inhibitors，Immunotherapy，2017年，Vol. 9, No. 16，pp. 1359-1372 |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
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| JP2024037880A (ja) * | 2018-03-28 | 2024-03-19 | ボード オブ リージェンツ ザ ユニヴァーシティ オブ テキサス システム | エフェクターｔ細胞をリプログラムするためのヒストン修飾因子の使用 |
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| WO2019191501A9 (en) | 2020-02-06 |
| JP2024037880A (ja) | 2024-03-19 |
| US20250145953A1 (en) | 2025-05-08 |
| WO2019191501A1 (en) | 2019-10-03 |
| EP3773626A4 (en) | 2022-01-05 |
| EP4722350A2 (en) | 2026-04-08 |
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| CA3094375A1 (en) | 2019-10-03 |
| AU2019243578B2 (en) | 2025-11-20 |
| EP3773626A1 (en) | 2021-02-17 |
| KR20200138325A (ko) | 2020-12-09 |
| CN112105368A (zh) | 2020-12-18 |
| JP2021519087A (ja) | 2021-08-10 |
| US12173317B2 (en) | 2024-12-24 |
| US20210189337A1 (en) | 2021-06-24 |
| EP3773626B1 (en) | 2026-01-28 |
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