JP7440934B2 - Ａｂｃｃ１１阻害剤 - Google Patents
Ａｂｃｃ１１阻害剤 Download PDFInfo
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- JP7440934B2 JP7440934B2 JP2021540992A JP2021540992A JP7440934B2 JP 7440934 B2 JP7440934 B2 JP 7440934B2 JP 2021540992 A JP2021540992 A JP 2021540992A JP 2021540992 A JP2021540992 A JP 2021540992A JP 7440934 B2 JP7440934 B2 JP 7440934B2
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- abcc11
- inhibitor
- carbon atoms
- branched alkyl
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- 238000012762 unpaired Student’s t-test Methods 0.000 description 1
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Images
Classifications
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/426—1,3-Thiazoles
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4196—1,2,4-Triazoles
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/494—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom
- A61K8/496—Triazoles or their condensed derivatives, e.g. benzotriazoles
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q15/00—Anti-perspirants or body deodorants
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
- A61K2800/92—Oral administration
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- Health & Medical Sciences (AREA)
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- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
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- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Dermatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Birds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Cosmetics (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962890053P | 2019-08-21 | 2019-08-21 | |
| US62/890,053 | 2019-08-21 | ||
| PCT/JP2020/031672 WO2021033773A1 (ja) | 2019-08-21 | 2020-08-21 | Ａｂｃｃ１１阻害剤 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPWO2021033773A1 JPWO2021033773A1 (https=) | 2021-02-25 |
| JP7440934B2 true JP7440934B2 (ja) | 2024-02-29 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021540992A Active JP7440934B2 (ja) | 2019-08-21 | 2020-08-21 | Ａｂｃｃ１１阻害剤 |
Country Status (5)
| Country | Link |
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| US (1) | US20220288038A1 (https=) |
| EP (1) | EP4019048A4 (https=) |
| JP (1) | JP7440934B2 (https=) |
| CN (1) | CN114341120A (https=) |
| WO (1) | WO2021033773A1 (https=) |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2007148835A1 (ja) | 2006-06-22 | 2007-12-27 | Nippon Chemiphar Co., Ltd. | 抗ガン剤耐性克服剤 |
| WO2018023126A1 (en) | 2016-07-29 | 2018-02-01 | Kaspar Roger L | Methods of treating osmidrosis |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2092580T3 (es) | 1990-11-30 | 1996-12-01 | Teijin Ltd | Derivado de 2-ariltiazol y composicion farmaceutica que contiene el mismo. |
| EP1206937B1 (en) * | 1999-07-16 | 2008-01-23 | Shoei Co., Ltd. | Nitroimidazole external preparations for the treatment of atopic dermatitis |
| DE10352511A1 (de) * | 2003-11-07 | 2005-06-16 | Ernst-Moritz-Arndt-Universität Greifswald | Verwendung von MRP4-Inhibitoren zur Behandlung und/oder Prophylaxe kardiovaskulärer Erkrankungen |
| WO2007018687A1 (en) * | 2005-07-21 | 2007-02-15 | University Of Florida Research Foundation, Inc. | Compositions and methods for treatment and prevention of hyperuricemia related health consequences |
| CN102093309B (zh) * | 2006-12-07 | 2012-07-04 | 重庆医药工业研究院有限责任公司 | 非布司他的晶型及其制备方法 |
| DE102008001811A1 (de) * | 2008-05-15 | 2009-11-19 | Beiersdorf Ag | Kosmetische Zubereitungen zur Verminderung von Schweißgeruch mit ABCC-Modulatoren |
| EP2582683B1 (en) * | 2010-06-15 | 2018-03-21 | Ardea Biosciences, Inc. | Treatment of gout and hyperuricemia |
| WO2012122532A2 (en) * | 2011-03-09 | 2012-09-13 | Biocryst Pharmaceuticals, Inc. | Compositions and methods for treatment of hyperuricemia |
| CN105399694B (zh) * | 2015-12-11 | 2017-09-15 | 浙江京新药业股份有限公司 | 药物Lesinurad轴手性对映体 |
| CN105949156A (zh) * | 2016-05-15 | 2016-09-21 | 刘雨 | 一种伊曲康唑的药物组合物及其医药用途 |
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2020
- 2020-08-21 US US17/636,151 patent/US20220288038A1/en not_active Abandoned
- 2020-08-21 CN CN202080058788.5A patent/CN114341120A/zh active Pending
- 2020-08-21 JP JP2021540992A patent/JP7440934B2/ja active Active
- 2020-08-21 EP EP20854802.4A patent/EP4019048A4/en not_active Withdrawn
- 2020-08-21 WO PCT/JP2020/031672 patent/WO2021033773A1/ja not_active Ceased
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2007148835A1 (ja) | 2006-06-22 | 2007-12-27 | Nippon Chemiphar Co., Ltd. | 抗ガン剤耐性克服剤 |
| WO2018023126A1 (en) | 2016-07-29 | 2018-02-01 | Kaspar Roger L | Methods of treating osmidrosis |
Non-Patent Citations (4)
| Title |
|---|
| EL-SHEIKH, AAK, et al.，Effect of hypouricaemic and hyperuricaemic drugs on the renal urate efflux transporter, multidrug re，British Journal of Pharmacology，2008年08月25日，Vol. 155，p. 1066-1075 |
| KEPPLER, Dietrich，Multidrug Resistance Proteins (MRPs, ABCCs): Importance for Pathophysiology and Drug Therapy，Handbook of Experimental Pharmacology，2010年10月26日，Vol. 201，p. 299-323 |
| SHEN, Zancong, et al.，In Vitro and In Vivo Interaction Studies Between Lesinurad, a Selective Urate Reabsorption Inhibitor，Clin. Drug Investig.，2016年03月07日，Vol. 36，p. 443-452 |
| Zhe-Sheng CHEN et al.，"Transport of Bile Acids, Sulfated Steroids, Estradiol 17-β-d-Glucuronide, and Leukotriene C4 by Human Multidrug Resistance Protein 8 (ABCC11)"，Molecular Pharmacology，2004年11月10日，Vol. 67, No. 2，p.545-557，DOI: 10.1124/mol.104.007138 |
Also Published As
| Publication number | Publication date |
|---|---|
| JPWO2021033773A1 (https=) | 2021-02-25 |
| US20220288038A1 (en) | 2022-09-15 |
| EP4019048A4 (en) | 2023-10-04 |
| CN114341120A (zh) | 2022-04-12 |
| WO2021033773A1 (ja) | 2021-02-25 |
| EP4019048A1 (en) | 2022-06-29 |
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