JP7421904B2 - Virus inactivator composition - Google Patents

Description

The present invention relates to a virus inactivator composition and a virus inactivation method.

Washing hands and the environment is considered to be one of the important preventive measures against viral infectious diseases such as influenza and colds. Among these, acute viral gastroenteritis and diarrhea are not only confirmed as mass infections in nursing homes, schools, hospitals, etc., but also mass infections caused by food poisoning through contaminated food in restaurants and cooking facilities. There have been many reports as well. Viruses that cause these include non-enveloped viruses such as norovirus, sapovirus, and rotavirus, and infection in children and the elderly may cause serious symptoms. Furthermore, the viruses that cause foot-and-mouth disease, which is a typical childhood infectious disease, and foot-and-mouth disease, which causes severe damage to livestock, are also classified as non-enveloped viruses, and hygiene measures for hands and the environment are extremely important as preventive measures against these viruses. be.

In particular, norovirus has been detected not only in Japan but also all over the world as a virus that causes non-bacterial food poisoning and acute gastroenteritis. Bacteria such as Staphylococcus aureus and Bacillus cereus have traditionally been known to cause food poisoning, but in recent years, food poisoning caused by norovirus, which causes acute gastroenteritis, accounts for about 25% of food poisoning cases and about 1,000 patients overall. It is the most common virus, accounting for half of the population, and is considered a problem as a virus that causes mass infections. It is well known that the route of infection is oral infection through eating raw oysters and other shellfish, but in homes and public facilities, infection can occur on the fingers or cooking utensils of people who have come into contact with contaminated food, or on patients' vomit or feces. There have also been many reports of secondary infections from viruses existing inside or in the patient's surrounding environment. In particular, such secondary infections lead to mass infections and spread of infection, and are a major cause of the increase in the number of patients.

Conventionally, various proposals have been made to inactivate viruses.
Patent Document 1 discloses a virucidal method in which a specific virucidal acid is brought into contact with a virus-containing region.
Patent Document 2 discloses an antibacterial composition that includes a proton donor and a surfactant and has a relaxation index, an antibacterial residual effectiveness index, and a 10-minute antiviral residual effectiveness index each within a predetermined range.
Patent Document 3 discloses an antibacterial composition containing an antibacterial active substance and an anionic surfactant mixture having an alkyl chain of a predetermined chain length.
US Pat. No. 5,001,203 discloses a method for inactivating viruses, comprising topically applying an antimicrobial composition comprising an organic acid and an anionic surfactant mixture having an alkyl chain of a predetermined chain length to the area requiring treatment. A method is disclosed.
Patent Document 5 describes a virus inactivating agent containing ethanol and an acid agent, the acid agent being at least two acids selected from the group consisting of citric acid, tartaric acid, and phosphoric acid, The virus inactivating agent has a pH of 1.0 to 6.0.
Patent Document 6 discloses that the antibacterial active substance, an anionic surfactant, a proton donor, and water are each contained in predetermined ranges, the pH is adjusted to about 3.0 to about 6.0, and the pH is greater than about 1.3. comprising a porous sheet or an absorbent sheet impregnated with an antimicrobial cleansing composition having a twice-wash instant bacterial reduction index and a mildness index greater than 0.3, including Gram-positive bacteria, Gram-negative bacteria, fungi, Antibacterial wipes are disclosed that are effective against yeast, mold and viruses.
Patent Document 7 discloses an inactivating agent for non-enveloped viruses that contains a specific quaternary ammonium salt as an active ingredient and has a pH in the range of 5 to 9.
Patent Document 8 discloses a decorative board having a substrate, a surface resin layer laminated on one or both surfaces of the substrate, and an organic antiviral agent disposed on the surface resin layer. The organic antiviral agent is described as an alkylbenzenesulfonic acid or a salt thereof.
Patent Document 9 discloses a virus inactivator containing ethanol, a predetermined cation, a predetermined anion, and an acid agent.

Japanese Unexamined Patent Publication No. 58-135802 Special Publication No. 2003-520809 Special Publication No. 2005-530857 Special Publication No. 2010-505964 Japanese Patent Application Publication No. 2018-199635 Special Publication No. 2002-541182 Japanese Patent Application Publication No. 2010-53091 JP2017-94544A Japanese Patent Application Publication No. 2018-197204

To prevent food poisoning and infection caused by norovirus, prevent food poisoning from occurring on the floors and walls of large-scale cooking facilities and kitchen spaces such as group feeding facilities and restaurants, food processing equipment, cooking utensils, etc., as well as floors and walls at home, and toilets. , implement hygiene measures such as removing and inactivating viruses from cooking utensils, furniture, textile products, etc., as well as floors and walls of public facilities, equipment, medical equipment, etc., and washing hands. are extremely important, and it is desirable that these measures be implemented easily and with consideration for people and the environment.

The present invention provides a virus inactivator composition that can inactivate viruses such as norovirus by a simple method.

The present invention provides (a) an anionic surfactant [hereinafter referred to as component (a)], and (b) ions of one or more metals selected from manganese, iron, cobalt, nickel, copper, and zinc [hereinafter referred to as component (a)]. The present invention relates to a virus inactivator composition containing component (b)] as an active ingredient.

The present invention also relates to a cleaning composition containing the virus inactivator composition of the present invention.

The present invention also relates to a hard surface cleaning composition containing the virus inactivator composition of the present invention.

The present invention also relates to a method for inactivating a virus, which comprises bringing the virus inactivator composition of the present invention into contact with the virus.

The present invention also relates to a cleaning method in which the cleaning composition of the present invention is brought into contact with virus-containing dirt.

According to the present invention, a virus inactivator composition that can inactivate viruses such as norovirus in a simple method and a method for inactivating viruses using the same are provided.

<Virus inactivator composition>
Component (a) is an anionic surfactant. The composition of the present invention contains component (a) as an effective ingredient for virus inactivation. One or more types of component (a) can be used.
Component (a) includes an anionic surfactant having a hydrocarbon group having 8 or more and 24 or less carbon atoms.
Examples of the hydrocarbon group of component (a) include an alkyl group and an alkenyl group. The hydrocarbon group may be either straight chain or branched chain.
From the viewpoint of virus inactivation, the hydrocarbon group of component (a) preferably has 8 or more carbon atoms, and preferably 24 or less, more preferably 18 or less, and still more preferably 14 or less.
In addition, in the case of a compound having a cyclic structure such as an aromatic hydrocarbon group, the hydrocarbon group of component (a) means a hydrocarbon group that replaces one of the hydrogen molecules of the cyclic structure. good.

As the component (a), an anionic surfactant having a hydrocarbon group having 8 to 24 carbon atoms and a sulfonic acid group or a sulfuric acid ester group can be mentioned. The sulfonic acid group or sulfuric acid ester group may be a salt.

(a) Components include benzenesulfonic acid or its salt having a hydrocarbon group having 8 to 24 carbon atoms substituting on the benzene ring, and sulfuric acid ester or its salt having a hydrocarbon group having 8 to 24 carbon atoms. One or more selected anionic surfactants may be mentioned.

Examples of the benzenesulfonic acid or salt thereof having a hydrocarbon group having 8 to 24 carbon atoms substituting on the benzene ring include alkylbenzenesulfonic acid having an alkyl group having 8 to 24 carbon atoms or a salt thereof. From the viewpoint of virus inactivation, the alkyl group has carbon atoms of 8 or more, preferably 10 or more, and 24 or less, preferably 18 or less, and more preferably 14 or less.

Examples of the sulfuric esters or salts thereof having a hydrocarbon group having 8 to 24 carbon atoms include alkyl sulfuric esters having an alkyl group having 8 to 24 carbon atoms or salts thereof. From the viewpoint of virus inactivation, the alkyl group has carbon atoms of 8 or more, preferably 10 or more, and 24 or less, preferably 18 or less, and more preferably 14 or less.

In addition, as component (a) other than these, α-sulfo fatty acid methyl ester or salt thereof whose fatty acid moiety has carbon atoms of 8 or more and 24 or less, preferably 9 or more and 24 or less, and an alkyl group whose carbon number is 8 or more and 24 or less The following polyoxyalkylene (preferably polyoxyethylene, average number of added moles is 0.5 or more, preferably 1 or more, and 4 or less, preferably 3 or less) alkyl ether sulfuric acid or its salt, the number of carbon atoms in the alkyl group is Alkylglyceryl sulfonate having 8 to 24 carbon atoms, olefin sulfonic acid or its salt having 8 to 24 carbon atoms in the olefin moiety, alkanesulfonic acid or its salt having 8 to 24 carbon atoms in the alkane moiety, alkyl group Examples include alkylsulfosuccinic acids or salts thereof having 8 or more and 24 or less carbon atoms.

Examples of the salt of component (a) include alkali metal salts such as sodium salts and potassium salts, and ammonium salts.

As component (a), from the viewpoint of virus inactivation, benzene sulfonic acid or a salt thereof having a hydrocarbon group having 8 to 24 carbon atoms to be substituted on the benzene ring, and a hydrocarbon group having 8 to 24 carbon atoms. Furthermore, preferred are sulfuric esters or salts thereof, alkylbenzenesulfonic acids or salts thereof having an alkyl group having 8 or more and 24 or less carbon atoms, and alkyl sulfuric esters or salts thereof having an alkyl group having 8 or more and 24 or less carbon atoms. As component (a), an alkyl sulfate having an alkyl group having 8 to 24 carbon atoms or a salt thereof is more preferable.

In the virus inactivator composition of the present invention, component (a) is preferably 0.01% by mass or more, more preferably 0.03% by mass or more, still more preferably 0.01% by mass or more, from the viewpoint of virus inactivation. 05% by mass or more, even more preferably 0.1% by mass or more, and from the viewpoint of virus inactivation and economic efficiency, preferably 5.0% by mass or less, more preferably 2.0% by mass or less, even more preferably is contained in an amount of 1.0% by mass or less, more preferably 0.9% by mass or less, still more preferably 0.6% by mass or less.

Component (b) is a metal ion selected from manganese, iron, cobalt, nickel, copper, and zinc. The composition of the present invention contains component (b) as an effective ingredient for virus inactivation. One or more types of component (b) can be used.
Component (b) is preferably a divalent ion from the viewpoint of virus inactivation.
From the viewpoint of virus inactivation, the component (b) includes Mn ²⁺ , Fe ²⁺ , Co ²⁺ , Ni ²⁺ , Cu ²⁺ , and Zn ²⁺ .
As the component (b), Cu ²⁺ and Zn ²⁺ are preferable because they have a high virus inactivating ability, and Zn ²⁺ is easier to handle because it does not have the coloring characteristic of transition elements when added to an aqueous composition and is transparent. preferable.

Component (b) can be incorporated into the virus inactivator composition of the present invention by blending a compound that dissociates into the predetermined metal ion in water, such as a salt of the metal. Examples of such compounds include sulfates, hydrochlorides, sulfides, and hydroxides of the metals. More specifically, zinc chloride, zinc sulfate, manganese sulfate, iron sulfate, cobalt sulfate, nickel sulfate, copper sulfate and the like can be mentioned.

The virus inactivator composition of the present invention preferably contains component (b) in an amount of 0.04% by mass or more, more preferably 0.08% by mass or more, still more preferably 0.04% by mass or more, from the viewpoint of virus inactivation. The content is 1% by mass or more, preferably 5.0% by mass or less, more preferably 3.0% by mass or less. The content of component (b) in the composition may be directly measured or calculated from the type and amount of the compound used as the source of component (b) when preparing the composition. As a method for measuring the content of component (b) in the composition, any known method for quantifying metal ions can be used without particular limitation, such as ion chromatography, ICP emission spectrometry, etc. Can be used.

In the virus inactivator composition of the present invention, (b)/(a) is the mass ratio between the content of component (b) and the content of component (a), from the viewpoint of virus inactivation. , preferably 0.03 or more, more preferably 0.05 or more, still more preferably 0.1 or more, even more preferably 0.25 or more, and preferably 25 or less, more preferably 20 or less, still more preferably 15 Below, it is still more preferably 10 or less, even more preferably 8 or less, even more preferably 4 or less.

In the present invention, by combining the anionic surfactant as the component (a) and the specific metal ion as the component (b), an excellent inactivation effect on viruses can be obtained. The effects of the present invention will not be effective if component (a) is combined with a metal ion that is not component (b), or if component (b) is combined with a surfactant that is not component (a). I can't get it. The virus inactivator composition of the present invention may contain a surfactant that is not the component (a) or a metal ion that is not the component (b) within a range that does not impair the effects of the present invention.

The virus inactivator composition of the present invention preferably contains (c) an organic acid [hereinafter referred to as component (c)]. One or more types of component (c) can be used.
From the viewpoint of virus inactivation, component (c) has a pKa of preferably 1.8 or more, more preferably 2.0 or more, even more preferably 2.5 or more, even more preferably 3.0 or more, and , preferably 5.0 or less, more preferably 4.5 or less, still more preferably 4.2 or less.
From the viewpoint of virus inactivation, component (c) is preferably an organic acid having 1 to 12 carbon atoms. The organic acid is preferably a carboxylic acid.
From the viewpoint of virus inactivation, component (c) is preferably an organic acid with a valence of 1 or more and 5 or less.
Component (c) is preferably a hydroxycarboxylic acid from the viewpoint of virus inactivation.

In addition, when producing the composition of the present invention, component (c) may be in the form of an acid or a salt. For example, the composition of the present invention may be manufactured using a salt of component (b).

In terms of virus inactivation, the components (c) include lactic acid (pKa=3.8), malic acid (pKa=3.4), succinic acid (pKa=4.2), and citric acid (pKa=3). .1), glycolic acid (pKa=3.8), tartaric acid (pKa=3.0), acetic acid (pKa=4.7), maleic acid (pKa=1.9), fumaric acid (pKa=3.0) ), preferably one or more organic acids selected from lactic acid, malic acid, succinic acid, and citric acid.

When the virus inactivator composition of the present invention contains component (c), (c)/(a) is the mass ratio of the content of component (c) to the content of component (a). , from the viewpoint of virus inactivation and workability during application, preferably 0.015 or more, more preferably 0.02 or more, even more preferably 0.05 or more, even more preferably 0.1 or more, and preferably is 300 or less, more preferably 100 or less, even more preferably 50 or less, even more preferably 20 or less, even more preferably 15 or less, even more preferably 10 or less, even more preferably 5 or less, even more preferably 3 or less , even more preferably 1.5 or less. Incidentally, the mass of component (c) of the present invention is based on a value converted to an acid type compound.

In the virus inactivator composition of the present invention, component (c) is preferably 0.01% by mass or more, more preferably 0.05% by mass or more, and still more preferably 0.01% by mass or more, from the viewpoint of virus inactivation. 1% by mass or more, even more preferably 0.2% by mass or more, even more preferably 0.25% by mass or more, even more preferably 0.4% by mass or more, and from the economical point of view, preferably 5. The content is 0% by mass or less, more preferably 3.0% by mass or less, even more preferably 1.0% by mass or less, even more preferably 0.95% by mass or less, still more preferably 0.9% by mass or less.

The virus inactivator composition of the present invention can contain water. If the composition is a liquid, water may be used as the balance of the composition.

The virus inactivator composition of the present invention can also contain components other than component (a), component (b), and optional component (c). For example, solvents, inorganic salts, inorganic acids, chelating agents, fragrances (natural fragrances, synthetic fragrances), thickeners, gelling agents, polymer compounds, humectants, preservatives, antioxidants, light stabilizers, preservatives. Components such as agents and buffers may be contained within the range that does not impair the effects of the present invention.

The virus inactivator composition of the present invention can be used, for example, in the form of a liquid, gel, or paste. Depending on the form of use thereof, the virus inactivator composition of the present invention, a solubilizing carrier such as water or alcohol, a gelling agent, etc. can be appropriately contained.

In the virus inactivator composition of the present invention, from the viewpoint of virus inactivation, the proportion of the content of component (a) in the total content of components other than water is preferably 3% by mass or more, and more preferably Preferably it is 5% by mass or more, more preferably 10% by mass or more, and preferably 95% by mass or less, more preferably 90% by mass or less, still more preferably 75% by mass or less, still more preferably 60% by mass or less.

The virus inactivator composition of the present invention preferably has a pH at 20°C measured by a glass electrode method, from the viewpoint of sufficiently expressing the virus inactivation effect and from the viewpoint of preventing corrosion of equipment, etc. .5 or more, more preferably 2.8 or more, still more preferably 3.0 or more, and preferably 7.0 or less, more preferably 6.0 or less, still more preferably 5.5 or less. In addition, the pH at 20°C of the virus inactivator composition of the present invention is a value measured as is when the virus inactivator composition of the present invention is a liquid such as an aqueous solution, and is a value measured directly when the virus inactivator composition of the present invention is a liquid such as an aqueous solution. In this case, the value in the state of a 2% by mass aqueous solution or aqueous dispersion is applied as the solid content concentration. Further, the virus inactivator composition of the present invention may be used at a pH within the above range. That is, it may be brought into contact with the virus at a pH within the above range.

The virus inactivator composition of the present invention can be applied to various viruses. The virus is preferably a non-enveloped virus, that is, a non-enveloped single-stranded (+) RNA virus, a single-stranded (-) RNA virus, a double-stranded RNA virus, a single-stranded DNA virus, and a double-stranded RNA virus. Examples include double-stranded DNA viruses. Examples of such viruses include viruses belonging to Caliciviridae, Picornaviridae, Parvoviridae, Papillomaviridae, Polyomaviridae, and Adenoviridae. Among the above, the composition of the present invention has an excellent inactivating effect on Caliciviridae viruses (single-stranded (+) viruses), and among Caliciviridae viruses, Vesivirus, Norovirus, and Sapovirus genus. It has an excellent inactivating effect on viruses belonging to the genus Vesivirus and the genus Norovirus.

Although the mechanism of action of the effect of the virus inactivator composition of the present invention has not been clearly elucidated, it is believed that viruses are formed by adsorption of the components (a) and (b) of the present invention to viruses. It is thought that the virus is inactivated by changing the structure of the protein. In particular, proteins have groups that coordinate with metals, but component (b) coordinates with the proteins that make up the virus, or replaces the metal ions that were originally coordinated, thereby inactivating the virus. It is thought that the oxidation effect will be further improved. Furthermore, when component (c) is contained, since component (c) has a buffering capacity, it is thought that the effect is stably expressed by reducing the fluctuation in pH in the environment where it acts on the virus. . Note that the present invention is not particularly limited to the above mechanism of action.

The virus inactivator composition of the present invention can be applied to (1) the body, such as human skin, fingers, hair, and the inside of the oral cavity, (2) food, such as the surface of food materials such as vegetables, and (3) hard articles. (4) Textile products, such as textile materials such as cloth and thread, and products manufactured using these materials, can be targeted. Examples of hard articles include hard surfaces such as bathrooms, toilets, kitchens, floors, doorknobs, tableware, food processing equipment, desks, chairs, walls, and the like. These hard articles may be used at home or in public facilities or factories, such as swimming pools, bathhouses, cafeterias, hospitals, etc.

<Virus inactivation method>
The present invention provides a method for inactivating viruses, which involves bringing the virus inactivator composition of the present invention into contact with viruses. The virus may be present in the target mentioned in the virus inactivator composition of the present invention.

There are no particular limitations on the form in which the virus inactivator composition of the present invention is used when it is brought into contact with viruses. In the present invention, it is preferable to use the virus inactivator composition of the present invention under conditions where component (a) and component (b) come into contact with the virus at a pH of 2.5 or higher and 7.0 or lower.

When the virus inactivator composition of the present invention is in liquid form, it can be used particularly as a spray, lotion, etc. For example, it is possible to fill a known spray container such as a trigger spray container (direct pressure or pressure accumulation type) or a dispenser-type pump spray container, adjust the amount of spray, and spray it to a place where the virus is present or is thought to be present. Examples include those made as follows.
It can also be used as a wet wiping product (wet napkin, etc.). For example, the virus inactivating agent of the present invention may be applied to a substrate containing natural fibers, recycled fibers such as rayon, synthetic fibers such as polyethylene, polypropylene, polyester, or a woven or nonwoven web of a mixture of natural fibers and synthetic fibers. The composition, a solubilizing carrier, and, if necessary, various additives can be included for use. Specifically, it can be used for sterilizing skin conditioners, pet care products, surfaces of home kitchens, bathrooms, toilets, toilet seats, etc., surfaces of exercise equipment, etc.

When the virus inactivator composition of the present invention is made into a gel form using a water-soluble gel or an oil-based gel, or when it is made into a paste form, it can be used as a medical product by directly applying it to the human body, pets, etc. It can also be used as a filter for air purifiers by supporting it on paper, nonwoven fabric, or the like.

The amount of the virus inactivator composition of the present invention to be used is not particularly limited, but for example, the amount of component (a) per 1 m ² of the target object is preferably 0.0001 g or more, or more. The amount can be preferably 0.001 g or more, and preferably 0.1 g or less, and more preferably 0.05 g or less.
Although the amount of the virus inactivator composition of the present invention to be used is not particularly limited, for example, the total amount of component (a) and component (b) per unit area of 1 m ² of the object is preferably 0.0005, more preferably 0.002 or more, and preferably 0.2 g or less, more preferably 0.1 g or less.

<Cleaning composition and cleaning method>
The virus inactivator composition of the present invention can be incorporated into a cleaning agent and used when cleaning virus-containing stains.
The present invention provides a cleaning composition containing the virus inactivator composition of the present invention.
The present invention also provides a hard surface cleaning composition containing the virus inactivator composition of the present invention.
In the cleaning composition of the present invention, as well as the hard surface cleaning composition, components and compositions other than the virus inactivator composition of the present invention are selected from known embodiments, taking into consideration the intended use and usage. be able to.

The present invention provides a cleaning method in which a cleaning composition of the present invention, such as a hard surface cleaning composition, is brought into contact with virus-containing soil.

The cleaning method of the present invention can be applied to the targets mentioned in the virus inactivator composition of the present invention.

The virus inactivator compositions shown in the table were prepared, and their inactivating effects on feline calicivirus (family Caliciviridae, genus Vesivirus), which is also known as a substitute virus for norovirus, were evaluated. In addition, the appearance of the composition immediately after preparation was visually observed to evaluate whether it was colored or transparent. In addition, the pH of the compositions in the table was adjusted to the values shown in the table using sodium hydroxide or hydrochloric acid, if necessary.

Virus inactivation evaluation is based on the "2015 Survey Report on Norovirus Inactivation Conditions" (National Institute of Health Sciences) and JIS L 1922, which are generally known as standard methods for virus inactivation evaluation. I went to
In an Eppendorf tube, 900 μL of the virus inactivator composition and 100 μL of a feline calicivirus solution (strain F-9, ATCC VR-782) adjusted to 1.0×10 ⁷ PFU/mL were added and mixed well. After a predetermined time (1 minute, 10 minutes) had passed, the reaction was stopped by diluting it 1/10 with a quenching liquid (D/E Neutralizing Broth). As a blank, the same operation was performed using 900 μL of physiological saline instead of 900 μL of the virus inactivator composition. After stopping the reaction, the mixture was further diluted 1/10 with DMEM medium (Dulbecco's modified Eagle medium), and 0.5 mL of the mixture was added to CRFK cells (feline kidney-derived cell line) washed with PBS (phosphate buffered saline). (ATCC CCL-94), and after 1 hour, the medium was replaced with methylcellulose-containing medium. Two days later, cells were stained with crystal violet for each sample at a predetermined time, and the number of plaques was counted to determine the amount of logarithmic reduction.
Logarithmic reduction = log (number of plaques on blank) - log (number of plaques on test sample)
In this specification, the logarithmic decrease amount is expressed as Δ4log, for example, when the logarithmic decrease amount=4. In this evaluation, the time required for the logarithmic decrease amount to reach Δ4log was evaluated. The criteria for evaluation were as follows, and the results are shown in the table.
Judgment criteria ◎:>The logarithmic reduction amount at an application time of 1 minute is greater than Δ4log ○:>The logarithmic reduction amount at an application time of 1 minute is smaller than Δ4log, but the logarithmic reduction amount at an application time of 10 minutes is greater than Δ4log is also large. △:>The logarithmic reduction amount in an application time of 10 minutes is larger than Δ1log and smaller than Δ4log ×: The logarithmic reduction amount in an application time of 10 minutes is Δ1log or less

The ingredients in the table are as follows. Component (a') is a comparison component of component (a). Component (b _x ) is a compound for blending component (b). Component (b') is a compound for blending a comparative component of component (b). The content of component (b) was calculated from the type and amount of component (b _x ). In Comparative Examples 1-4 to 1-6 in Table 1, the amount of metal ions blended from component (b') is shown as the content of component (b).
・SDS: Sodium lauryl sulfate (EMAL 0 (Kao Corporation))
・LAS: Sodium p-octylbenzenesulfonate (Wako Pure Chemical Industries, Ltd.)
・AG: Lauryl glucoside (Mydol 12 (Kao Corporation))

Claims (8)

(a) One or more types of anionic surfactants selected from benzenesulfonic acid or a salt thereof having a hydrocarbon group having 8 to 24 carbon atoms, and a sulfuric acid ester or a salt thereof having a hydrocarbon group having 8 to 24 carbon atoms. (hereinafter referred to as component (a)) , ( b ) copper , and zinc [hereinafter referred to as component (b)] as active ingredients, and contains water . A composition ,
Contains component (a) from 0.1% by mass to 2.0% by mass,
(b) Contains 0.08% by mass or more and 3.0% by mass or less of the component,
(b)/(a), which is the mass ratio between the content of component (b) and the content of component (a), is 0.1 or more and 25 or less,
pH at 20°C is 2.5 or more and 6.0 or less,
Virus inactivator composition. The virus inactivator composition according to claim 1 , further comprising (c) an organic acid having a pKa of 1.8 or more and 5.0 or less [hereinafter referred to as component (c)]. The virus inactivator composition according to claim 2 , which contains component (c) from 0.01% by mass to 5.0% by mass. The virus inactivator composition according to any one of claims 1 to 3 , wherein the virus is non-enveloped. A cleaning composition comprising the virus inactivator composition according to any one of claims 1 to 4 . A hard surface cleaning composition comprising the virus inactivator composition according to any one of claims 1 to 4 . A method for inactivating a virus (excluding medical treatment for humans) , which comprises bringing the virus inactivator composition according to any one of claims 1 to 4 into contact with a virus. A cleaning method comprising bringing the cleaning composition according to claim 5 or 6 into contact with virus-containing dirt.