JP7392954B2 - トリプルネガティブ乳癌の治療方法 - Google Patents
トリプルネガティブ乳癌の治療方法 Download PDFInfo
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- JP7392954B2 JP7392954B2 JP2020536930A JP2020536930A JP7392954B2 JP 7392954 B2 JP7392954 B2 JP 7392954B2 JP 2020536930 A JP2020536930 A JP 2020536930A JP 2020536930 A JP2020536930 A JP 2020536930A JP 7392954 B2 JP7392954 B2 JP 7392954B2
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- A61K48/005—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of the 'active' part of the composition delivered, i.e. the nucleic acid delivered
- A61K48/0066—Manipulation of the nucleic acid to modify its expression pattern, e.g. enhance its duration of expression, achieved by the presence of particular introns in the delivered nucleic acid
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- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/444—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring heteroatom, e.g. amrinone
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- C12N15/09—Recombinant DNA-technology
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- C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
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- C12Y207/11—Protein-serine/threonine kinases (2.7.11)
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- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/16011—Human Immunodeficiency Virus, HIV
- C12N2740/16041—Use of virus, viral particle or viral elements as a vector
- C12N2740/16043—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
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- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
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- G01N33/57407—Specifically defined cancers
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762560140P | 2017-09-18 | 2017-09-18 | |
| US62/560,140 | 2017-09-18 | ||
| PCT/US2018/051489 WO2019055977A1 (en) | 2017-09-18 | 2018-09-18 | METHODS OF TREATING NEGATIVE TRIPLE BREAST CANCER |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2020534354A JP2020534354A (ja) | 2020-11-26 |
| JP2020534354A5 JP2020534354A5 (enExample) | 2021-10-28 |
| JP7392954B2 true JP7392954B2 (ja) | 2023-12-06 |
Family
ID=65723126
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020536930A Active JP7392954B2 (ja) | 2017-09-18 | 2018-09-18 | トリプルネガティブ乳癌の治療方法 |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US11471477B2 (enExample) |
| EP (1) | EP3684420A4 (enExample) |
| JP (1) | JP7392954B2 (enExample) |
| CN (1) | CN111278469A (enExample) |
| AU (1) | AU2018333072B2 (enExample) |
| WO (1) | WO2019055977A1 (enExample) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP4401840A4 (en) * | 2021-09-16 | 2025-09-24 | Univ South Carolina | CDK8/19 INHIBITORS FOR THE PREVENTION OF DRUG RESISTANCE |
| CN114908168A (zh) * | 2022-05-04 | 2022-08-16 | 重庆大学附属肿瘤医院 | 一种mon1a表达水平检测试剂在制备卵巢癌干性诊断试剂中的应用 |
| CN114854755B (zh) * | 2022-05-30 | 2023-05-23 | 陕西师范大学 | 一种抑制vstm2l表达的慢病毒载体及其应用 |
| CN114832110B (zh) * | 2022-06-21 | 2023-04-28 | 中山大学孙逸仙纪念医院 | 长链非编码rna crcal-3抑制剂在制备治疗放疗抵抗乳腺癌的产品中的用途 |
| EP4616004A1 (en) * | 2022-11-07 | 2025-09-17 | Cbsbioscience, Co., Ltd | Methods and compositions for predicting and treating triple negative breast cancer |
| JPWO2024106394A1 (enExample) * | 2022-11-14 | 2024-05-23 | ||
| WO2025020931A1 (en) * | 2023-07-21 | 2025-01-30 | The Chinese University Of Hong Kong | Cdk20 in cancer diagnosis and therapy |
| CN116773815B (zh) * | 2023-08-14 | 2023-11-10 | 四川省医学科学院·四川省人民医院 | Slc2a6作为治疗靶点和筛查靶点的用途及乳腺癌筛查试剂盒 |
| CN117144008B (zh) * | 2023-08-31 | 2024-03-08 | 武汉科技大学 | 三阴性乳腺癌生物标志物及其应用 |
| CN118001402B (zh) * | 2024-01-10 | 2025-09-05 | 中山大学 | Pacsin2在促进sting信号通路激活中的应用 |
| CN119264251B (zh) * | 2024-12-09 | 2025-03-14 | 上海交通大学医学院附属仁济医院 | 一种cbln1单克隆抗体和应用 |
| CN120309727B (zh) * | 2025-06-13 | 2025-08-15 | 昆明医科大学 | 一种靶向人igfl1的单域抗体及其应用 |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2015506376A (ja) | 2012-02-02 | 2015-03-02 | セネックス バイオテクノロジー インク.Senex Biotechnology Inc. | Cdk8/cdk19選択的阻害剤、ならびに癌のための抗転移および化学防御の方法におけるそれらの使用 |
| WO2018139660A1 (ja) | 2017-01-30 | 2018-08-02 | 国立大学法人京都大学 | 新規化合物及び制御性t細胞の製造方法 |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| US4704692A (en) | 1986-09-02 | 1987-11-03 | Ladner Robert C | Computer based system and method for determining and displaying possible chemical structures for converting double- or multiple-chain polypeptides to single-chain polypeptides |
| US20080293142A1 (en) | 2007-04-19 | 2008-11-27 | The Board Of Regents For Oklahoma State University | Multiple shRNA Expression Vectors and Methods of Construction |
| US20130053426A1 (en) | 2009-04-17 | 2013-02-28 | Yiqi Seow | Composition For Delivery Of Genetic Material |
| US8598344B2 (en) | 2009-11-30 | 2013-12-03 | Senex Biotechnology | CDKI pathway inhibitors and uses thereof |
| MX2013005661A (es) * | 2010-11-19 | 2013-09-13 | Piramal Entpr Ltd | Combinacion farmaceutica de paclitaxel y un inhibidor cdk (quinasa dependiente de ciclina). |
| SG11201401343YA (en) | 2011-09-13 | 2014-08-28 | Igor Roninson | TREATMENT OF DISEASE OR DISORDERS CAUSED BY INDUCED NFkB TRANSCRIPTIONAL ACTIVITY |
| MX391815B (es) | 2011-11-18 | 2025-03-21 | Alnylam Pharmaceuticals Inc | AGENTES DE iARN, COMPOSICIONES Y METODOS DE LOS MISMOS PARA USARSE EN EL TRATAMIENTO DE ENFERMEDADES ASOCIADAS CON TRANSTITERINA (TTR). |
| GB201121069D0 (en) | 2011-12-07 | 2012-01-18 | Isis Innovation | Delivery system |
| CA2890108C (en) | 2012-11-01 | 2021-03-02 | University Of South Carolina | Method for treating prostate cancer |
| WO2015002956A1 (en) | 2013-07-01 | 2015-01-08 | Ohio State Innovation Foundation | Exosome delivery system |
| US20170115308A1 (en) | 2014-11-14 | 2017-04-27 | Senex Biotechnology, Inc. | Assay to measure efficacy of cdk8/19 inhibitors |
| UY36363A (es) * | 2015-01-19 | 2016-04-01 | Takeda Pharmaceutical | Compuesto heterocíclico fusionado |
| TW201714883A (zh) * | 2015-10-16 | 2017-05-01 | 武田藥品工業股份有限公司 | 雜環化合物 |
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2018
- 2018-09-18 AU AU2018333072A patent/AU2018333072B2/en active Active
- 2018-09-18 US US16/648,088 patent/US11471477B2/en active Active
- 2018-09-18 CN CN201880060608.XA patent/CN111278469A/zh active Pending
- 2018-09-18 WO PCT/US2018/051489 patent/WO2019055977A1/en not_active Ceased
- 2018-09-18 EP EP18856034.6A patent/EP3684420A4/en active Pending
- 2018-09-18 JP JP2020536930A patent/JP7392954B2/ja active Active
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2022
- 2022-08-29 US US17/823,028 patent/US20230285439A1/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2015506376A (ja) | 2012-02-02 | 2015-03-02 | セネックス バイオテクノロジー インク.Senex Biotechnology Inc. | Cdk8/cdk19選択的阻害剤、ならびに癌のための抗転移および化学防御の方法におけるそれらの使用 |
| WO2018139660A1 (ja) | 2017-01-30 | 2018-08-02 | 国立大学法人京都大学 | 新規化合物及び制御性t細胞の製造方法 |
Non-Patent Citations (1)
| Title |
|---|
| Cancer Res.,2016年07月15日,Vol. 76 (14_Supplement),Abstract 4355 |
Also Published As
| Publication number | Publication date |
|---|---|
| AU2018333072B2 (en) | 2022-09-29 |
| JP2020534354A (ja) | 2020-11-26 |
| CN111278469A (zh) | 2020-06-12 |
| AU2018333072A1 (en) | 2020-03-26 |
| US11471477B2 (en) | 2022-10-18 |
| WO2019055977A1 (en) | 2019-03-21 |
| CA3075784A1 (en) | 2019-03-21 |
| EP3684420A1 (en) | 2020-07-29 |
| US20210121495A1 (en) | 2021-04-29 |
| US20230285439A1 (en) | 2023-09-14 |
| EP3684420A4 (en) | 2021-06-16 |
| WO2019055977A9 (en) | 2019-04-25 |
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