JP7391863B2 - プロゲステロン膣内デバイス - Google Patents

プロゲステロン膣内デバイス Download PDF

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Publication number
JP7391863B2
JP7391863B2 JP2020550751A JP2020550751A JP7391863B2 JP 7391863 B2 JP7391863 B2 JP 7391863B2 JP 2020550751 A JP2020550751 A JP 2020550751A JP 2020550751 A JP2020550751 A JP 2020550751A JP 7391863 B2 JP7391863 B2 JP 7391863B2
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JP
Japan
Prior art keywords
progesterone
ring
vaginal
intravaginal
polymorphic form
Prior art date
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Application number
JP2020550751A
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English (en)
Japanese (ja)
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JP2021518405A (ja
JP2021518405A5 (https=
Inventor
マルゴ、コンセプシオン ニエト
エルナンド、エレナ ペレス
デル プラド、ハイメ モスコソ
アルマルサ、ハビエル スアレス
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ITF Research Pharma SL
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ITF Research Pharma SL
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Publication date
Application filed by ITF Research Pharma SL filed Critical ITF Research Pharma SL
Publication of JP2021518405A publication Critical patent/JP2021518405A/ja
Publication of JP2021518405A5 publication Critical patent/JP2021518405A5/ja
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
    • A61K9/0036—Devices retained in the vagina or cervix for a prolonged period, e.g. intravaginal rings, medicated tampons, medicated diaphragms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/12—Drugs for genital or sexual disorders; Contraceptives for climacteric disorders

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Reproductive Health (AREA)
  • Epidemiology (AREA)
  • Gynecology & Obstetrics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Endocrinology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Inorganic Chemistry (AREA)
  • Pregnancy & Childbirth (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Orthopedics, Nursing, And Contraception (AREA)
  • Media Introduction/Drainage Providing Device (AREA)
JP2020550751A 2018-03-21 2019-03-21 プロゲステロン膣内デバイス Active JP7391863B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP18382190.9A EP3542786A1 (en) 2018-03-21 2018-03-21 Progesterone intravaginal devices
EP18382190.9 2018-03-21
PCT/EP2019/057074 WO2019180133A1 (en) 2018-03-21 2019-03-21 Progesterone intravaginal devices

Publications (3)

Publication Number Publication Date
JP2021518405A JP2021518405A (ja) 2021-08-02
JP2021518405A5 JP2021518405A5 (https=) 2022-03-14
JP7391863B2 true JP7391863B2 (ja) 2023-12-05

Family

ID=61768237

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2020550751A Active JP7391863B2 (ja) 2018-03-21 2019-03-21 プロゲステロン膣内デバイス

Country Status (7)

Country Link
US (1) US11278491B2 (https=)
EP (2) EP3542786A1 (https=)
JP (1) JP7391863B2 (https=)
KR (1) KR102844796B1 (https=)
CN (1) CN112469392A (https=)
CA (1) CA3094420C (https=)
WO (1) WO2019180133A1 (https=)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3542786A1 (en) 2018-03-21 2019-09-25 ITF Research Pharma, S.L.U. Progesterone intravaginal devices
MX2021011885A (es) * 2019-03-29 2022-04-18 Juniper Pharmaceuticals Inc N/K/A Catalent Jnp Inc Anillos intravaginales segmentados de eva que contienen progesterona.

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2002504507A (ja) 1998-02-25 2002-02-12 ジョン クロード サヴォワール 結晶性有機化合物の安定な成形粒子
JP2011510984A (ja) 2008-02-04 2011-04-07 テバ ウィメンズ ヘルス インコーポレイテッド プロゲステロンを含むモノリシック膣内リングならびにそれらの製造方法および使用
US20170224823A1 (en) 2014-10-22 2017-08-10 International Partnership For Microbicides, Inc. Platinum-catalyzed silicone drug delivery devices and methods of use thereof

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4816257A (en) * 1985-09-20 1989-03-28 Research & Education Institute, Harbor-Ucla Medical Center Inc. Method for producing an in vivo environment suitable for human embryo transfer
US5869081A (en) 1996-06-28 1999-02-09 The Population Council Progesterone vaginal ring for treatment of infertility
US6476079B1 (en) * 1999-12-23 2002-11-05 Leiras Oy Devices for the delivery of drugs having antiprogestinic properties
EP3542786A1 (en) 2018-03-21 2019-09-25 ITF Research Pharma, S.L.U. Progesterone intravaginal devices

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2002504507A (ja) 1998-02-25 2002-02-12 ジョン クロード サヴォワール 結晶性有機化合物の安定な成形粒子
JP2011510984A (ja) 2008-02-04 2011-04-07 テバ ウィメンズ ヘルス インコーポレイテッド プロゲステロンを含むモノリシック膣内リングならびにそれらの製造方法および使用
US20170224823A1 (en) 2014-10-22 2017-08-10 International Partnership For Microbicides, Inc. Platinum-catalyzed silicone drug delivery devices and methods of use thereof

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
APPS PharmSciTech，2010年，11(3)，pp.1493-1498
International Journal of Pharmaceutics，2009年，382，pp.98-103

Also Published As

Publication number Publication date
WO2019180133A1 (en) 2019-09-26
JP2021518405A (ja) 2021-08-02
KR20200135443A (ko) 2020-12-02
CN112469392A (zh) 2021-03-09
RU2020131251A (ru) 2022-04-22
EP3542786A1 (en) 2019-09-25
KR102844796B1 (ko) 2025-08-08
US20210030666A1 (en) 2021-02-04
US11278491B2 (en) 2022-03-22
EP3768235A1 (en) 2021-01-27
CA3094420C (en) 2024-06-25
CA3094420A1 (en) 2019-09-26

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