JP7389551B2 - Metエキソン14欠失の検出と、関連する治療法 - Google Patents

Metエキソン14欠失の検出と、関連する治療法 Download PDF

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JP7389551B2
JP7389551B2 JP2018559197A JP2018559197A JP7389551B2 JP 7389551 B2 JP7389551 B2 JP 7389551B2 JP 2018559197 A JP2018559197 A JP 2018559197A JP 2018559197 A JP2018559197 A JP 2018559197A JP 7389551 B2 JP7389551 B2 JP 7389551B2
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exon
probe
met
met exon
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チェング シンディ
ヒルマン グラントランド
マックス マ シャオジュ
マノーハー チャイトラ
ウォン リリー
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F Hoffmann La Roche AG
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    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
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    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
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    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/16Primer sets for multiplex assays

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  • Chemical & Material Sciences (AREA)
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JP2018559197A 2016-05-13 2017-05-11 Metエキソン14欠失の検出と、関連する治療法 Active JP7389551B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201662336362P 2016-05-13 2016-05-13
US62/336,362 2016-05-13
PCT/EP2017/061310 WO2017194668A1 (en) 2016-05-13 2017-05-11 Detection of met exon 14 deletions and associated therapies

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JP2019520802A JP2019520802A (ja) 2019-07-25
JP2019520802A5 JP2019520802A5 (enExample) 2020-04-16
JP7389551B2 true JP7389551B2 (ja) 2023-11-30

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US (1) US11913072B2 (enExample)
EP (1) EP3455375B1 (enExample)
JP (1) JP7389551B2 (enExample)
CN (1) CN109072293A (enExample)
CA (1) CA3023839A1 (enExample)
ES (1) ES2978995T3 (enExample)
WO (1) WO2017194668A1 (enExample)

Families Citing this family (11)

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Publication number Priority date Publication date Assignee Title
WO2019195268A2 (en) 2018-04-02 2019-10-10 Grail, Inc. Methylation markers and targeted methylation probe panels
CN108929908A (zh) * 2018-07-17 2018-12-04 张丽英 一种基于数字PCR平台c-MET基因Exon14跳读的检测方法
AU2019351130B2 (en) 2018-09-27 2025-10-23 GRAIL, Inc Methylation markers and targeted methylation probe panel
WO2021041764A2 (en) * 2019-08-28 2021-03-04 An Hsu Kit and methods to detect met gene fusion
US11211144B2 (en) 2020-02-18 2021-12-28 Tempus Labs, Inc. Methods and systems for refining copy number variation in a liquid biopsy assay
US11475981B2 (en) 2020-02-18 2022-10-18 Tempus Labs, Inc. Methods and systems for dynamic variant thresholding in a liquid biopsy assay
US11211147B2 (en) 2020-02-18 2021-12-28 Tempus Labs, Inc. Estimation of circulating tumor fraction using off-target reads of targeted-panel sequencing
CN114107490B (zh) * 2020-08-26 2024-06-21 北京仁诚神经肿瘤生物技术工程研究中心有限公司 评价患者对met抑制剂敏感性的试剂盒
KR102616916B1 (ko) * 2021-05-11 2023-12-21 주식회사 애이마 발암성 돌연변이 유전자 검출용 가이드 rna 내지 이의 용도
CN116970686A (zh) * 2023-05-23 2023-10-31 上海奕检医学检验实验室有限公司 基于QSEP检测c-MET基因14号外显子跳跃突变的检测方法
CN117230204A (zh) * 2023-11-15 2023-12-15 神州医疗科技股份有限公司 一种用于检测met基因14外显子剪接突变的引物探针组、试剂盒和检测系统

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2008520228A (ja) 2004-11-24 2008-06-19 セント ジョージズ エンタープライゼズ リミテッド 前立腺癌の診断

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Publication number Priority date Publication date Assignee Title
CA2491067A1 (en) * 2004-12-24 2006-06-24 Stichting Katholieke Universiteit Mrna rations in urinary sediments and/or urine as a prognostic marker for prostate cancer
US8975019B2 (en) * 2009-10-19 2015-03-10 University Of Massachusetts Deducing exon connectivity by RNA-templated DNA ligation/sequencing
US20130122484A1 (en) * 2011-10-01 2013-05-16 Life Technologies Corporation Diagnostic method for determining animals persistently infected (pi) with bovine viral diarrhea virus (bvdv)

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2008520228A (ja) 2004-11-24 2008-06-19 セント ジョージズ エンタープライゼズ リミテッド 前立腺癌の診断

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
Clinical Cancer Research,2016年,Vol.22,No.4,pp.915-922
JOURNAL OF CLINICAL ONCOLOGY,2016年 1月 4日,34(7),pp.721-730
Journal of Clinical Pathology,2013年 6月25日,Vol.66,pp.985-991
Oncotarget,2015年 9月10日,6(29),pp.28211-28222
PLOS ONE,2014年,Vol.9,No.11,e110780,pp.1-7

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US20170327887A1 (en) 2017-11-16
ES2978995T3 (es) 2024-09-23
EP3455375A1 (en) 2019-03-20
JP2019520802A (ja) 2019-07-25
CN109072293A (zh) 2018-12-21
EP3455375B1 (en) 2024-03-13
US11913072B2 (en) 2024-02-27
CA3023839A1 (en) 2017-11-16
WO2017194668A1 (en) 2017-11-16

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