JP7300719B2 - 成体多能性幹細胞の調製、拡大および使用 - Google Patents

成体多能性幹細胞の調製、拡大および使用 Download PDF

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JP7300719B2
JP7300719B2 JP2019554507A JP2019554507A JP7300719B2 JP 7300719 B2 JP7300719 B2 JP 7300719B2 JP 2019554507 A JP2019554507 A JP 2019554507A JP 2019554507 A JP2019554507 A JP 2019554507A JP 7300719 B2 JP7300719 B2 JP 7300719B2
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cells
cell
alternatively
stem cells
purified
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JP2020512816A (ja
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リ、シャオウェイ
フ、ミン
ピーター ロレンツ、ハーマン
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Leland Stanford Junior University
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Leland Stanford Junior University
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0607—Non-embryonic pluripotent stem cells, e.g. MASC
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/28—Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/30—Nerves; Brain; Eyes; Corneal cells; Cerebrospinal fluid; Neuronal stem cells; Neuronal precursor cells; Glial cells; Oligodendrocytes; Schwann cells; Astroglia; Astrocytes; Choroid plexus; Spinal cord tissue
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2502/00—Coculture with; Conditioned medium produced by
    • C12N2502/14—Coculture with; Conditioned medium produced by hepatocytes

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Cell Biology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Biotechnology (AREA)
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  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Virology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Hematology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Ophthalmology & Optometry (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
JP2019554507A 2017-04-04 2018-04-03 成体多能性幹細胞の調製、拡大および使用 Active JP7300719B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201762481554P 2017-04-04 2017-04-04
US62/481,554 2017-04-04
PCT/US2018/025846 WO2018187298A1 (fr) 2017-04-04 2018-04-03 Préparation, expansion et utilisations de cellules souches pluripotentes adultes

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JP2020512816A JP2020512816A (ja) 2020-04-30
JP7300719B2 true JP7300719B2 (ja) 2023-06-30

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JP2019554507A Active JP7300719B2 (ja) 2017-04-04 2018-04-03 成体多能性幹細胞の調製、拡大および使用

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US (2) US20210380937A1 (fr)
EP (2) EP4154710A1 (fr)
JP (1) JP7300719B2 (fr)
CN (1) CN110546251A (fr)
WO (1) WO2018187298A1 (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11845956B2 (en) 2018-09-21 2023-12-19 APstem Therapeutics, Inc. Human pluripotent adult stem cells

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4683195A (en) 1986-01-30 1987-07-28 Cetus Corporation Process for amplifying, detecting, and/or-cloning nucleic acid sequences
ES2654251T3 (es) * 2006-04-19 2018-02-12 Ludwig-Maximilians-Universität München Hormona paratiroidea (PTH) para su utilización en el tratamiento de la isquemia
WO2008033469A1 (fr) 2006-09-15 2008-03-20 Children's Medical Center Corporation Procédés de production de cellules souches embryonnaires à partir d'embryons parthénogénétiques
AU2008236638A1 (en) 2007-04-06 2008-10-16 International Stem Cell Corporation Patient-specific stem cell lines derived from human parthenogenetic blastocysts
WO2009075856A1 (fr) * 2007-12-10 2009-06-18 The Board Of Trustees Of The Leland Stanford Junior University Cellules de point régénératives
EP3150701B1 (fr) * 2009-06-05 2018-10-03 FUJIFILM Cellular Dynamics, Inc. Reprogrammation de lymphocytes t et de cellules hématopoïétiques
WO2016004087A1 (fr) * 2014-06-30 2016-01-07 Primegen Biotech Llc Cellules souches de sous-populations dérivées des gonades
US11845956B2 (en) * 2018-09-21 2023-12-19 APstem Therapeutics, Inc. Human pluripotent adult stem cells

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
Experimental Hematology，2007年，Vol.35，pp.1872-1883

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Publication number Publication date
US20210380937A1 (en) 2021-12-09
EP4154710A1 (fr) 2023-03-29
EP3606341A1 (fr) 2020-02-12
CN110546251A (zh) 2019-12-06
JP2020512816A (ja) 2020-04-30
US20230021683A1 (en) 2023-01-26
EP3606341A4 (fr) 2021-04-21
WO2018187298A1 (fr) 2018-10-11

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