JP7263313B2 - 併用される抗真菌剤 - Google Patents

併用される抗真菌剤 Download PDF

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JP7263313B2
JP7263313B2 JP2020504267A JP2020504267A JP7263313B2 JP 7263313 B2 JP7263313 B2 JP 7263313B2 JP 2020504267 A JP2020504267 A JP 2020504267A JP 2020504267 A JP2020504267 A JP 2020504267A JP 7263313 B2 JP7263313 B2 JP 7263313B2
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compound
therapeutic agent
pharmaceutical combination
pharmaceutically acceptable
combination
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JP2020513037A5 (enExample
JP2020513037A (ja
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アングロ・ゴンザレス,デイビット・エー
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サイネクシス,インコーポレーテッド
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/41961,2,4-Triazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10Antimycotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
JP2020504267A 2017-04-10 2018-04-04 併用される抗真菌剤 Active JP7263313B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2022205904A JP7574268B2 (ja) 2017-04-10 2022-12-22 併用される抗真菌剤

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201762483647P 2017-04-10 2017-04-10
US62/483,647 2017-04-10
PCT/US2018/026088 WO2018191077A1 (en) 2017-04-10 2018-04-04 Antifungal agents used in combination

Related Child Applications (1)

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JP2022205904A Division JP7574268B2 (ja) 2017-04-10 2022-12-22 併用される抗真菌剤

Publications (3)

Publication Number Publication Date
JP2020513037A JP2020513037A (ja) 2020-04-30
JP2020513037A5 JP2020513037A5 (enExample) 2021-05-13
JP7263313B2 true JP7263313B2 (ja) 2023-04-24

Family

ID=62063223

Family Applications (2)

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JP2020504267A Active JP7263313B2 (ja) 2017-04-10 2018-04-04 併用される抗真菌剤
JP2022205904A Active JP7574268B2 (ja) 2017-04-10 2022-12-22 併用される抗真菌剤

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JP2022205904A Active JP7574268B2 (ja) 2017-04-10 2022-12-22 併用される抗真菌剤

Country Status (13)

Country Link
US (2) US11110102B2 (enExample)
EP (1) EP3609539A1 (enExample)
JP (2) JP7263313B2 (enExample)
KR (2) KR102683355B1 (enExample)
CN (1) CN110769854B (enExample)
AR (1) AR113221A1 (enExample)
AU (1) AU2018253031B2 (enExample)
CA (1) CA3059225A1 (enExample)
EA (1) EA201992413A1 (enExample)
MA (1) MA49889A (enExample)
MX (1) MX2019012116A (enExample)
TW (1) TWI806861B (enExample)
WO (1) WO2018191077A1 (enExample)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3661503B1 (en) * 2017-08-04 2022-09-07 Scynexis, Inc. Antifungal agents with enhanced activity in acidic ph
CN113631165A (zh) * 2019-02-27 2021-11-09 西尼克斯公司 用于治疗或预防肺囊虫属肺炎的三萜类抗真菌剂
CA3140637A1 (en) * 2019-05-16 2020-11-19 Scynexis, Inc. Antifungal agents, like ibrexafungerp for candida auris decolonization

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2011530593A (ja) 2008-08-12 2011-12-22 メルク・シャープ・エンド・ドーム・コーポレイション 抗真菌剤

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5756472A (en) 1996-01-31 1998-05-26 Merck & Co., Inc. Antifungal agent obtained from hormonema
AU2007245024B2 (en) 2006-04-03 2012-09-06 Scynexis, Inc. Antifungal agents
EA018337B1 (ru) * 2008-08-12 2013-07-30 Мерк Шарп Энд Дом Корп. Противогрибковые средства
AU2015348043B2 (en) * 2014-11-21 2019-08-22 F2G Limited Antifungal agents
US10174074B2 (en) 2015-01-19 2019-01-08 Scynexis, Inc. Salts and polymorphs of SCY-078

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2011530593A (ja) 2008-08-12 2011-12-22 メルク・シャープ・エンド・ドーム・コーポレイション 抗真菌剤

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
Antimicrobial Agents and Chemotherapy,2013年,57,1065-1068
Antimicrobial Agents and Chemotherapy,2013年,57,4656-4663
Antimicrobial Agents and Chemotherapy,2013年,57,5778-5780
Journal of Antimicrobuial Chemotherapy,2016年,71,3135-3147
Journal of Infectious Diseases,2003年,187,1834-1843

Also Published As

Publication number Publication date
TW201842915A (zh) 2018-12-16
EP3609539A1 (en) 2020-02-19
JP7574268B2 (ja) 2024-10-28
WO2018191077A1 (en) 2018-10-18
JP2023030113A (ja) 2023-03-07
AR113221A1 (es) 2020-02-19
MX2019012116A (es) 2019-11-21
TWI806861B (zh) 2023-07-01
CA3059225A1 (en) 2018-10-18
AU2018253031B2 (en) 2024-04-11
BR112019021138A2 (pt) 2020-05-12
US20220202833A1 (en) 2022-06-30
KR20240110109A (ko) 2024-07-12
US11110102B2 (en) 2021-09-07
EA201992413A1 (ru) 2020-03-16
MA49889A (fr) 2020-06-24
KR102683355B1 (ko) 2024-07-10
CN110769854A (zh) 2020-02-07
JP2020513037A (ja) 2020-04-30
US20180325919A1 (en) 2018-11-15
KR20190133251A (ko) 2019-12-02
CN110769854B (zh) 2023-01-13
AU2018253031A1 (en) 2019-10-31

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