JP7248368B2 - 高度に特異的な環状近接ライゲーションアッセイ - Google Patents

高度に特異的な環状近接ライゲーションアッセイ Download PDF

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JP7248368B2
JP7248368B2 JP2019543321A JP2019543321A JP7248368B2 JP 7248368 B2 JP7248368 B2 JP 7248368B2 JP 2019543321 A JP2019543321 A JP 2019543321A JP 2019543321 A JP2019543321 A JP 2019543321A JP 7248368 B2 JP7248368 B2 JP 7248368B2
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ヘンリク エイチ．ジェイ． パーソン，
ロクサナ ジャリリ，
ジョセフ エル． ホレッカ，
ロナルド ダブリュー． デイビス，
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Leland Stanford Junior University
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    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
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    • C12Q1/6851—Quantitative amplification
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    • C12Q2521/501—Ligase
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    • C12Q2523/00—Reactions characterised by treatment of reaction samples
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    • C12Q2531/00—Reactions of nucleic acids characterised by
    • C12Q2531/10—Reactions of nucleic acids characterised by the purpose being amplify/increase the copy number of target nucleic acid
    • C12Q2531/125—Rolling circle
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    • C12Q2537/00—Reactions characterised by the reaction format or use of a specific feature
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    • C12Q2537/162—Helper probe
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    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
    • G01N33/542—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with steric inhibition or signal modification, e.g. fluorescent quenching

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  • Chemical Kinetics & Catalysis (AREA)
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  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
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JP2019543321A 2017-03-01 2018-02-20 高度に特異的な環状近接ライゲーションアッセイ Active JP7248368B2 (ja)

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US201762465320P 2017-03-01 2017-03-01
US62/465,320 2017-03-01
PCT/US2018/018859 WO2018160397A1 (en) 2017-03-01 2018-02-20 Highly specific circular proximity ligation assay

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EP3589750B1 (en) 2022-05-04
ES2917500T3 (es) 2022-07-08
JP2020511629A (ja) 2020-04-16
US11530438B2 (en) 2022-12-20
US20190360025A1 (en) 2019-11-28
US20230295691A1 (en) 2023-09-21
WO2018160397A1 (en) 2018-09-07
CA3053384A1 (en) 2018-09-07
EP3589750A1 (en) 2020-01-08
EP3589750A4 (en) 2020-11-04

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