JP7236380B2 - 治療に適したtalエフェクターヌクレアーゼ(talen)改変同種異系細胞 - Google Patents

治療に適したtalエフェクターヌクレアーゼ(talen)改変同種異系細胞 Download PDF

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JP7236380B2
JP7236380B2 JP2019520685A JP2019520685A JP7236380B2 JP 7236380 B2 JP7236380 B2 JP 7236380B2 JP 2019520685 A JP2019520685 A JP 2019520685A JP 2019520685 A JP2019520685 A JP 2019520685A JP 7236380 B2 JP7236380 B2 JP 7236380B2
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tcr
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sequence
talen
receptor
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JP2019531742A (ja
JP2019531742A5 (enExample
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フィリップ ドゥシャトー
ブライアン ビュッセル
アレクサンドル ジュイレラット
アンヌ-ソフィ ゴートラン
ローラント ポアロ
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Cellectis SA
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JP2019520685A 2016-10-19 2017-10-19 治療に適したtalエフェクターヌクレアーゼ(talen)改変同種異系細胞 Active JP7236380B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201662410187P 2016-10-19 2016-10-19
US62/410,187 2016-10-19
DKPA201770240 2017-03-31
DKPA201770240 2017-03-31
PCT/EP2017/076800 WO2018073393A2 (en) 2016-10-19 2017-10-19 Tal-effector nuclease (talen) -modified allogenic cells suitable for therapy

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JP2019531742A JP2019531742A (ja) 2019-11-07
JP2019531742A5 JP2019531742A5 (enExample) 2023-01-25
JP7236380B2 true JP7236380B2 (ja) 2023-03-09

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US (1) US12655451B2 (enExample)
EP (1) EP3529265A2 (enExample)
JP (1) JP7236380B2 (enExample)
AU (1) AU2017347685B2 (enExample)
CA (1) CA3041039A1 (enExample)

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EA202191257A1 (ru) 2018-11-07 2021-12-06 Криспр Терапьютикс Аг Противораковая терапия на основе иммуноцитов, связывающих liv1
US20230332104A1 (en) * 2020-06-11 2023-10-19 Novartis Ag Zbtb32 inhibitors and uses thereof
CN117129690B (zh) * 2023-09-26 2025-06-06 杭州师范大学 Grhl1在her2-乳腺癌诊断及预后评估中的应用

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2015136001A1 (en) 2014-03-11 2015-09-17 Cellectis Method for generating t-cells compatible for allogenic transplantation
WO2016124765A1 (en) 2015-02-06 2016-08-11 Cellectis Primary hematopoietic cells genetically engineered by slow release of nucleic acids using nanoparticles
JP2016525888A (ja) 2013-05-29 2016-09-01 セレクティスCellectis Rnaガイドcasヌクレアーゼ系を用いることによって免疫療法のためにt細胞を操作するための方法
WO2016160721A1 (en) 2015-03-27 2016-10-06 President And Fellows Of Harvard College Modified t cells and methods of making and using the same

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SG10201806573TA (en) * 2012-05-25 2018-09-27 Cellectis Methods for engineering allogeneic and immunosuppressive resistant t cell for immunotherapy
ES2803728T3 (es) * 2015-10-05 2021-01-29 Prec Biosciences Inc Células genéticamente modificadas que comprenden un gen de región constante alfa del receptor de linfocitos T humano modificado
SG11201808457PA (en) * 2016-04-15 2018-10-30 Alpine Immune Sciences Inc Icos ligand variant immunomodulatory proteins and uses thereof

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2016525888A (ja) 2013-05-29 2016-09-01 セレクティスCellectis Rnaガイドcasヌクレアーゼ系を用いることによって免疫療法のためにt細胞を操作するための方法
WO2015136001A1 (en) 2014-03-11 2015-09-17 Cellectis Method for generating t-cells compatible for allogenic transplantation
WO2016124765A1 (en) 2015-02-06 2016-08-11 Cellectis Primary hematopoietic cells genetically engineered by slow release of nucleic acids using nanoparticles
WO2016160721A1 (en) 2015-03-27 2016-10-06 President And Fellows Of Harvard College Modified t cells and methods of making and using the same

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
Cancer Research,2015年,Vol.75, No.18,pp.3853-3864

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EP3529265A2 (en) 2019-08-28
JP2019531742A (ja) 2019-11-07
AU2017347685B2 (en) 2023-08-03
US12655451B2 (en) 2026-06-16
US20230138915A1 (en) 2023-05-04
CA3041039A1 (en) 2018-04-26
AU2017347685A1 (en) 2019-05-02

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