JP7224586B2 - 免疫力の評価方法 - Google Patents
免疫力の評価方法 Download PDFInfo
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- JP7224586B2 JP7224586B2 JP2019002621A JP2019002621A JP7224586B2 JP 7224586 B2 JP7224586 B2 JP 7224586B2 JP 2019002621 A JP2019002621 A JP 2019002621A JP 2019002621 A JP2019002621 A JP 2019002621A JP 7224586 B2 JP7224586 B2 JP 7224586B2
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健康な成人18名を対象として、顔面頬部の肌の角層水分量はコルネオメーター(Courage+Khazaka社)で、顔面頬部の肌の経表皮水分蒸散量はテヴァメーター(Courage+Khazaka社)で、疲労感はVAS法(日本疲労学会の疲労感VAS検査用紙)で測定した。血液中のNK細胞活性は、採血で得た末梢血を用いて、放射性物質51Crを使用した、51Cr遊離法で測定した。測定項目間の統計解析は、積率相関係数および無相関検定p値(*p<0.05)を算出することで行った。
健康な成人18名を対象として、唾液を採取し、唾液中のストレス因子を測定した。唾液中アミラーゼ(α-アミラーゼ)は酵素活性測定キット(サリメトリクス社)で、唾液中コルチゾールおよび唾液中免疫グロブリンAはELISA(Enzyme-Linked Immuno Sorbent Assay)で測定した。測定項目間の統計解析は、積率相関係数および無相関検定p値(*p<0.05)を算出することで行った。
健康な成人18名を対象として、季節ごと「春(5月)、夏(8月)、秋(11月)、冬(2月)」の血液中NK細胞活性の測定を行った。血液中のNK細胞活性は、採血で得た末梢血を用いて、放射性物質51Crを使用した、51Cr遊離法で測定した。
Claims (1)
- 血液中ナチュラルキラー(NK)細胞活性を推定するための指標を得る方法であって、血液中ナチュラルキラー(NK)細胞活性を推定するための指標として、顔面頬部の肌の角層水分量を測定する方法。
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JP7224586B2 true JP7224586B2 (ja) | 2023-02-20 |
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Citations (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20040054265A1 (en) | 2002-09-13 | 2004-03-18 | Conopco, Inc. | Psychological stress in humans |
JP2004307425A (ja) | 2003-04-10 | 2004-11-04 | Nonogawa Shoji Kk | 抗ストレス剤 |
JP2007189951A (ja) | 2006-01-19 | 2007-08-02 | Kinji Ishida | 黒米発酵食品 |
WO2007145333A1 (ja) | 2006-06-15 | 2007-12-21 | National University Corporation, Tokyo Medical And Dental University | 免疫力評価方法、免疫力評価装置、免疫力評価プログラム、及び免疫力評価プログラムを記録した情報記録媒体 |
JP2010145205A (ja) | 2008-12-18 | 2010-07-01 | Tokyo Medical & Dental Univ | 免疫力評価方法、装置、及びプログラム |
WO2014132982A1 (ja) | 2013-02-27 | 2014-09-04 | 株式会社明治 | ストレス軽減剤 |
JP2016069285A (ja) | 2014-09-26 | 2016-05-09 | 株式会社アミノアップ化学 | 免疫促進組成物 |
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Patent Citations (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20040054265A1 (en) | 2002-09-13 | 2004-03-18 | Conopco, Inc. | Psychological stress in humans |
JP2004307425A (ja) | 2003-04-10 | 2004-11-04 | Nonogawa Shoji Kk | 抗ストレス剤 |
JP2007189951A (ja) | 2006-01-19 | 2007-08-02 | Kinji Ishida | 黒米発酵食品 |
WO2007145333A1 (ja) | 2006-06-15 | 2007-12-21 | National University Corporation, Tokyo Medical And Dental University | 免疫力評価方法、免疫力評価装置、免疫力評価プログラム、及び免疫力評価プログラムを記録した情報記録媒体 |
JP2010145205A (ja) | 2008-12-18 | 2010-07-01 | Tokyo Medical & Dental Univ | 免疫力評価方法、装置、及びプログラム |
WO2014132982A1 (ja) | 2013-02-27 | 2014-09-04 | 株式会社明治 | ストレス軽減剤 |
JP2016069285A (ja) | 2014-09-26 | 2016-05-09 | 株式会社アミノアップ化学 | 免疫促進組成物 |
Non-Patent Citations (3)
Title |
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免疫力測定評価基準,2016年10月23日,http://web.archive.org/web/20161023165211/http://h-ls.jp/check13.html |
永田頌史,ストレスによる免疫能の変化と脳・免疫連関,産業医科大学雑誌,1993年,Vol.15 No.2,Page.161-171 |
田中喜秀,薬学領域におけるストレス研究の最前線,ライフサポート,2010年,Vol.22 No.3,Page.90-95 |
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