JP7208898B2 - 癌を処置するための併用療法 - Google Patents

癌を処置するための併用療法 Download PDF

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JP7208898B2
JP7208898B2 JP2019529251A JP2019529251A JP7208898B2 JP 7208898 B2 JP7208898 B2 JP 7208898B2 JP 2019529251 A JP2019529251 A JP 2019529251A JP 2019529251 A JP2019529251 A JP 2019529251A JP 7208898 B2 JP7208898 B2 JP 7208898B2
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pharmaceutically acceptable
acceptable salt
tazemetostat
combination
administered
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JP2020500872A5 (https=
JP2020500872A (ja
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アレハンドラ ライモンディ マリア
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エピザイム，インコーポレイティド
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
    • A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
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    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
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    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
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    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
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  • Nutrition Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Endocrinology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
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  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
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JP2019529251A 2016-12-02 2017-12-01 癌を処置するための併用療法 Active JP7208898B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2022192010A JP2023022228A (ja) 2016-12-02 2022-11-30 癌を処置するための併用療法

Applications Claiming Priority (11)

Application Number Priority Date Filing Date Title
US201662429612P 2016-12-02 2016-12-02
US62/429,612 2016-12-02
US201762444326P 2017-01-09 2017-01-09
US62/444,326 2017-01-09
US201762466968P 2017-03-03 2017-03-03
US62/466,968 2017-03-03
US201762530781P 2017-07-10 2017-07-10
US62/530,781 2017-07-10
US201762567542P 2017-10-03 2017-10-03
US62/567,542 2017-10-03
PCT/US2017/064222 WO2018102687A2 (en) 2016-12-02 2017-12-01 Combination therapy for treating cancer

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JP2022192010A Division JP2023022228A (ja) 2016-12-02 2022-11-30 癌を処置するための併用療法

Publications (3)

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JP2020500872A JP2020500872A (ja) 2020-01-16
JP2020500872A5 JP2020500872A5 (https=) 2021-01-14
JP7208898B2 true JP7208898B2 (ja) 2023-01-19

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US (2) US20200078362A1 (https=)
EP (1) EP3548032A2 (https=)
JP (2) JP7208898B2 (https=)
AU (2) AU2017367768A1 (https=)
WO (1) WO2018102687A2 (https=)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
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JO3363B1 (ar) 2011-04-13 2019-03-13 Epizyme Inc مركبات بنزين مستبدلة بأريل أو أريل غير متجانس
CA3025933A1 (en) 2016-06-01 2017-12-07 Epizyme, Inc. Use of ezh2 inhibitors for treating cancer
WO2018183885A1 (en) 2017-03-31 2018-10-04 Epizyme, Inc. Combination therapy for treating cancer
AU2018275123A1 (en) 2017-06-02 2020-01-30 Epizyme, Inc. Use of EZH2 inhibitors for treating cancer
CN111093660A (zh) 2017-09-05 2020-05-01 Epizyme股份有限公司 用于治疗癌症的组合疗法
US20220362254A1 (en) * 2019-08-22 2022-11-17 Thomas Jefferson University Methods for reprogramming cancer cells
WO2021063332A1 (zh) * 2019-09-30 2021-04-08 江苏恒瑞医药股份有限公司 一种ezh2抑制剂与cdk4/6抑制剂联合在制备治疗肿瘤药物中的用途
US20220395575A1 (en) * 2019-11-14 2022-12-15 H. Lee Moffitt Cancer Center And Research Institute, Inc. Combination therapy with protein kinase b activation inhibitor to treat cancer
WO2023111810A1 (en) * 2021-12-14 2023-06-22 Pfizer Inc. Combination therapies and uses for treating cancer
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