JP7193874B2 - 筋肉Aキナーゼアンカータンパク質(mAKAP)作用の阻害による心臓病の処置 - Google Patents

筋肉Aキナーゼアンカータンパク質(mAKAP)作用の阻害による心臓病の処置 Download PDF

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JP7193874B2
JP7193874B2 JP2020521498A JP2020521498A JP7193874B2 JP 7193874 B2 JP7193874 B2 JP 7193874B2 JP 2020521498 A JP2020521498 A JP 2020521498A JP 2020521498 A JP2020521498 A JP 2020521498A JP 7193874 B2 JP7193874 B2 JP 7193874B2
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rsk3
makap
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makapβ
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マイケル エス. カピロフ,
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Kapiloff Michael S
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JP2020521498A 2017-07-06 2018-07-05 筋肉Aキナーゼアンカータンパク質(mAKAP)作用の阻害による心臓病の処置 Active JP7193874B2 (ja)

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US201762529224P 2017-07-06 2017-07-06
US62/529,224 2017-07-06
PCT/US2018/040913 WO2019010301A1 (en) 2017-07-06 2018-07-05 TREATMENT OF CARDIOPATHIES BY INHIBITING THE ACTION OF PROTEINS FROM ANCHORING TO MUSCLE PROTEIN KINASES A (MAKAP)

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JP2020527167A JP2020527167A (ja) 2020-09-03
JP2020527167A5 JP2020527167A5 (https=) 2021-08-05
JP7193874B2 true JP7193874B2 (ja) 2022-12-21

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US9132174B2 (en) 2013-03-15 2015-09-15 Anchored Rsk3 Inhibitors, Llc Treatment of heart disease by inhibition of the action of ribosomal S6 kinase 3 (RSK3)
WO2020051296A1 (en) * 2018-09-06 2020-03-12 Icahn School Of Medicine At Mount Sinai Compositions and methods for the treatment of heart disease
CA3139974A1 (en) * 2019-05-15 2020-11-19 University Of Miami Treatment of heart disease by disruption of the anchoring of pp2a
EP4103214B1 (en) 2020-02-13 2026-04-29 Tenaya Therapeutics, Inc. Gene therapy vectors for treating heart disease
JP2026505638A (ja) * 2023-02-13 2026-02-16 シーアールアイ バイオテック,インコーポレイテッド 心筋細胞における選択的発現のためのヒトトロポニンt遺伝子のプロモーター-エンハンサー配列

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US20140286928A1 (en) 2013-03-15 2014-09-25 Anchored Rsk3 Inhibitors, Llc Treatment of heart disease by inhibition of the action of ribosomal s6 kinase 3 (rsk3)

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US6489125B1 (en) 2000-05-10 2002-12-03 The Trustees Of Columbia University In The City Of New York Methods for identifying chemical compounds that inhibit dissociation of FKBP12.6 binding protein from type 2 ryanodine receptor
AU2003295600A1 (en) * 2002-11-14 2004-06-15 Dharmacon, Inc. Functional and hyperfunctional sirna
JP2007505158A (ja) * 2003-05-21 2007-03-08 ボード オブ リージェンツ ザ ユニバーシティー オブ テキサス システム 心肥大および心不全の処置としてのプロテインキナーゼC−μ(PKD)の阻害
US9217155B2 (en) * 2008-05-28 2015-12-22 University Of Massachusetts Isolation of novel AAV'S and uses thereof
US8734809B2 (en) * 2009-05-28 2014-05-27 University Of Massachusetts AAV's and uses thereof
US20130136729A1 (en) 2011-11-11 2013-05-30 University of Virginia Patent Foundation, d/b/a University of Virginia Licensing & Ventures Group Compositions and methods for targeting and treating diseases and injuries using adeno-associated virus vectors

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US20140286928A1 (en) 2013-03-15 2014-09-25 Anchored Rsk3 Inhibitors, Llc Treatment of heart disease by inhibition of the action of ribosomal s6 kinase 3 (rsk3)

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Title
Journal of Cell Science,2005年,Vol.118, No.23,pp.5637-5646

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ES2958662T3 (es) 2024-02-13
WO2019010301A1 (en) 2019-01-10
AU2018297274A1 (en) 2020-01-23
AU2018297274B2 (en) 2023-05-18
CA3065816A1 (en) 2019-01-10
JP2020527167A (ja) 2020-09-03
WO2019010301A8 (en) 2020-05-22
CA3065816C (en) 2024-11-19
EP3658157A1 (en) 2020-06-03
EP3658157B1 (en) 2023-07-26
US20190010493A1 (en) 2019-01-10
US10907153B2 (en) 2021-02-02

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