JP7184761B2 - アデノシン５’－ヌクレオチダーゼの阻害剤 - Google Patents

アデノシン５’－ヌクレオチダーゼの阻害剤 Download PDF

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JP7184761B2
JP7184761B2 JP2019517777A JP2019517777A JP7184761B2 JP 7184761 B2 JP7184761 B2 JP 7184761B2 JP 2019517777 A JP2019517777 A JP 2019517777A JP 2019517777 A JP2019517777 A JP 2019517777A JP 7184761 B2 JP7184761 B2 JP 7184761B2
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JP2019529500A5 (OSRAM
JP2019529500A (ja
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ピエール ポール デビアン ローラン
カリシアク ヤロスラフ
ブイ．ローソン ケネス
レディ レレティ マンモハン
アレン リンジー エリック
ハーディング マイルズ ディロン
ニューカム エリック
パトリック パワーズ ジェイ
リード ローゼン ブランドン
ウル シャリフ イーヘサン
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アーカス バイオサイエンシズ インコーポレイティド
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    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
    • A61K31/7076—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines containing purines, e.g. adenosine, adenylic acid
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    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals
    • C07H19/167—Purine radicals with ribosyl as the saccharide radical
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    • C07H19/16—Purine radicals
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    • C07H19/207—Purine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids the phosphoric or polyphosphoric acids being esterified by a further hydroxylic compound, e.g. flavine adenine dinucleotide or nicotinamide-adenine dinucleotide
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JP2019517777A 2016-10-03 2017-10-02 アデノシン５’－ヌクレオチダーゼの阻害剤 Active JP7184761B2 (ja)

Priority Applications (1)

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JP2022158467A JP2022173493A (ja) 2016-10-03 2022-09-30 アデノシン５’－ヌクレオチダーゼの阻害剤

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201662403598P 2016-10-03 2016-10-03
US62/403,598 2016-10-03
PCT/US2017/054694 WO2018067424A1 (en) 2016-10-03 2017-10-02 Inhibitors of adenosine 5'-nucleotidase

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JP2019529500A JP2019529500A (ja) 2019-10-17
JP2019529500A5 JP2019529500A5 (OSRAM) 2021-04-15
JP7184761B2 true JP7184761B2 (ja) 2022-12-06

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JP2022158467A Withdrawn JP2022173493A (ja) 2016-10-03 2022-09-30 アデノシン５’－ヌクレオチダーゼの阻害剤

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US (3) US11058704B2 (OSRAM)
EP (1) EP3518934A4 (OSRAM)
JP (2) JP7184761B2 (OSRAM)
CN (1) CN110049767B (OSRAM)
TW (1) TWI781960B (OSRAM)
WO (1) WO2018067424A1 (OSRAM)

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KR20210144821A (ko) 2019-03-29 2021-11-30 아르커스 바이오사이언시즈 인코포레이티드 규명된 아데노신 지문을 이용한 암의 치료방법
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CR20220611A (es) 2020-06-02 2023-06-07 Arcus Biosciences Inc Anticuerpos anti-tigit
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JP2024521706A (ja) 2021-05-21 2024-06-04 アーカス バイオサイエンシーズ，インコーポレーテッド Ａｘｌ化合物
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JP2025516262A (ja) 2022-05-02 2025-05-27 アーカス バイオサイエンシズ インコーポレイティド 抗ｔｉｇｉｔ抗体及びその使用
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