JP7173986B2 - 鼻移植片、送達工具、システム、及び使用の方法 - Google Patents
鼻移植片、送達工具、システム、及び使用の方法 Download PDFInfo
- Publication number
- JP7173986B2 JP7173986B2 JP2019555872A JP2019555872A JP7173986B2 JP 7173986 B2 JP7173986 B2 JP 7173986B2 JP 2019555872 A JP2019555872 A JP 2019555872A JP 2019555872 A JP2019555872 A JP 2019555872A JP 7173986 B2 JP7173986 B2 JP 7173986B2
- Authority
- JP
- Japan
- Prior art keywords
- nasal
- implant
- implants
- elongated member
- graft
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/18—Internal ear or nose parts, e.g. ear-drums
- A61F2/186—Nose parts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B17/24—Surgical instruments, devices or methods for use in the oral cavity, larynx, bronchial passages or nose; Tongue scrapers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B17/34—Trocars; Puncturing needles
- A61B17/3468—Trocars; Puncturing needles for implanting or removing devices, e.g. prostheses, implants, seeds, wires
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/0059—Cosmetic or alloplastic implants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/18—Internal ear or nose parts, e.g. ear-drums
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/58—Materials at least partially resorbable by the body
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B17/24—Surgical instruments, devices or methods for use in the oral cavity, larynx, bronchial passages or nose; Tongue scrapers
- A61B2017/246—Surgical instruments, devices or methods for use in the oral cavity, larynx, bronchial passages or nose; Tongue scrapers for cleaning of the nose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2210/00—Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2210/0004—Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof bioabsorbable
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2220/00—Fixations or connections for prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2220/0008—Fixation appliances for connecting prostheses to the body
- A61F2220/0016—Fixation appliances for connecting prostheses to the body with sharp anchoring protrusions, e.g. barbs, pins, spikes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2250/00—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2250/0014—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof having different values of a given property or geometrical feature, e.g. mechanical property or material property, at different locations within the same prosthesis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2250/00—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2250/0014—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof having different values of a given property or geometrical feature, e.g. mechanical property or material property, at different locations within the same prosthesis
- A61F2250/0018—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof having different values of a given property or geometrical feature, e.g. mechanical property or material property, at different locations within the same prosthesis differing in elasticity, stiffness or compressibility
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2250/00—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2250/0014—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof having different values of a given property or geometrical feature, e.g. mechanical property or material property, at different locations within the same prosthesis
- A61F2250/0029—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof having different values of a given property or geometrical feature, e.g. mechanical property or material property, at different locations within the same prosthesis differing in bending or flexure capacity
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2210/00—Anatomical parts of the body
- A61M2210/06—Head
- A61M2210/0618—Nose
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Otolaryngology (AREA)
- Heart & Thoracic Surgery (AREA)
- Biomedical Technology (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Engineering & Computer Science (AREA)
- Transplantation (AREA)
- Surgery (AREA)
- Cardiology (AREA)
- Pulmonology (AREA)
- Vascular Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Molecular Biology (AREA)
- Medical Informatics (AREA)
- Chemical & Material Sciences (AREA)
- Pathology (AREA)
- Dermatology (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Dentistry (AREA)
- Prostheses (AREA)
- Surgical Instruments (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2022177378A JP7569363B2 (ja) | 2017-04-13 | 2022-11-04 | 鼻移植片、送達工具、システム、及び使用の方法 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762485309P | 2017-04-13 | 2017-04-13 | |
| US62/485,309 | 2017-04-13 | ||
| PCT/US2018/027560 WO2018191659A1 (en) | 2017-04-13 | 2018-04-13 | Nasal implants, delivery tools, systems, and methods of use |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022177378A Division JP7569363B2 (ja) | 2017-04-13 | 2022-11-04 | 鼻移植片、送達工具、システム、及び使用の方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2020516398A JP2020516398A (ja) | 2020-06-11 |
| JP2020516398A5 JP2020516398A5 (enExample) | 2021-05-20 |
| JP7173986B2 true JP7173986B2 (ja) | 2022-11-17 |
Family
ID=63793653
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019555872A Active JP7173986B2 (ja) | 2017-04-13 | 2018-04-13 | 鼻移植片、送達工具、システム、及び使用の方法 |
| JP2022177378A Active JP7569363B2 (ja) | 2017-04-13 | 2022-11-04 | 鼻移植片、送達工具、システム、及び使用の方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022177378A Active JP7569363B2 (ja) | 2017-04-13 | 2022-11-04 | 鼻移植片、送達工具、システム、及び使用の方法 |
Country Status (7)
| Country | Link |
|---|---|
| US (3) | US11241306B2 (enExample) |
| EP (1) | EP3609432B1 (enExample) |
| JP (2) | JP7173986B2 (enExample) |
| CN (2) | CN110730642B (enExample) |
| AU (2) | AU2018251992B2 (enExample) |
| CA (1) | CA3059439A1 (enExample) |
| WO (1) | WO2018191659A1 (enExample) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2018132159A2 (en) * | 2016-11-03 | 2018-07-19 | Spirox, Inc. | Minimally invasive nasal implants and systems and methods |
| EP4574065A3 (en) | 2017-03-28 | 2025-08-20 | Stryker Corporation | Nasal delivery tools |
| US11554027B2 (en) * | 2018-09-10 | 2023-01-17 | Siesta Medical, Inc. | Systems and methods for nasal support |
| CN111449807B (zh) * | 2020-03-25 | 2023-05-26 | 深圳市大族三维科技有限公司 | 鼻假体适用性的判定方法、装置、终端设备及存储介质 |
| KR102402338B1 (ko) * | 2020-12-01 | 2022-05-26 | 유성식 | 코 성형 보형물 및 이를 이용한 코 성형방법 |
| DE102022120193B3 (de) | 2022-08-10 | 2023-10-05 | Heinz Kurz Gmbh | Verbessertes Septum-Implantat mit einem zentralen Rückenabschnitt und drei Teilabschnitten |
| DE102024101972B3 (de) | 2024-01-24 | 2025-03-13 | Heinz Kurz Gmbh | Einseitiges Septum-Implantat mit Splint |
| DE202024100349U1 (de) | 2024-01-24 | 2024-03-26 | Heinz Kurz Gmbh | Einseitiges Septum-Implantat mit Splint |
| DE202024100800U1 (de) | 2024-02-20 | 2024-03-26 | Heinz Kurz Gmbh | Einseitiges Implantat zur Spreizung eines Nasenflügels |
| DE102024104626B3 (de) | 2024-02-20 | 2025-07-10 | Heinz Kurz Gmbh | Einseitiges Implantat zur Spreizung eines Nasenflügels |
| CN117838233B (zh) * | 2024-03-04 | 2024-06-18 | 诺一迈尔(山东)医学科技有限公司 | 鼻中隔固定支架及鼻中隔固定支架系统 |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20070270899A1 (en) | 2006-05-17 | 2007-11-22 | Awengen Daniel | Implant for spreading the nasal wings |
| US20110251634A1 (en) | 2008-11-19 | 2011-10-13 | Gonzales Donald A | Apparatus and methods for correcting nasal valve collapse |
| WO2016033196A1 (en) | 2014-08-26 | 2016-03-03 | Spirox, Inc. | Nasal implants and systems and method of use |
Family Cites Families (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20030166107A1 (en) | 1997-09-18 | 2003-09-04 | Genentech, Inc. | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
| US6322590B1 (en) | 1999-11-09 | 2001-11-27 | Michael J. Sillers | Internal nasal implant |
| US8403954B2 (en) * | 2001-05-22 | 2013-03-26 | Sanostec Corp. | Nasal congestion, obstruction relief, and drug delivery |
| DE20307058U1 (de) * | 2003-05-07 | 2003-08-14 | Heinz Kurz GmbH Medizintechnik, 72144 Dußlingen | Implantat zur Spreizung der Nasenflügel |
| US7750914B2 (en) | 2004-08-26 | 2010-07-06 | Intel Corporation | Subdividing geometry images in graphics hardware |
| US7947076B2 (en) * | 2005-06-03 | 2011-05-24 | Medtronic Xomed, Inc. | Nasal valve treatment method and apparatus |
| US8038712B2 (en) * | 2006-06-29 | 2011-10-18 | Koninklijke Philips Electronics N.V. | Methods and devices for rhinoplasty and treating internal valve stenosis |
| MX2009000409A (es) | 2006-07-10 | 2009-05-11 | Sinexus Inc | Dispositivo para administracion sostenida de farmacos que se puede implantar para liberar agentes activos al complejo osteomeatal. |
| US7780730B2 (en) * | 2006-09-25 | 2010-08-24 | Iyad Saidi | Nasal implant introduced through a non-surgical injection technique |
| CN101199867B (zh) * | 2006-12-15 | 2012-08-22 | 张建军 | 医用泡沫硅橡胶制备方法及医用植入假体 |
| EP3103502A1 (en) | 2009-05-15 | 2016-12-14 | Intersect ENT, Inc. | Expandable devices and methods therefor |
| WO2011008981A1 (en) * | 2009-07-15 | 2011-01-20 | Regents Of The University Of Minnesota | Implantable devices for treatment of sinusitis |
| WO2011119084A1 (en) * | 2010-03-23 | 2011-09-29 | Sanda Hadziavdic | Adjustable nasal implant |
| US8480737B2 (en) * | 2010-09-27 | 2013-07-09 | Ethicon, Inc. | Columellar strut for nasal tip support |
| US9510940B2 (en) * | 2011-02-17 | 2016-12-06 | Ethicon, Inc. | Bioabsorbable multilayer nasal valve spreader graft |
| US20130317540A1 (en) * | 2012-05-22 | 2013-11-28 | Krasimira Hristov | Universal bioabsorbable nasal implant kit |
| DE102012107123B4 (de) * | 2012-08-03 | 2015-03-19 | Heinz Kurz Gmbh Medizintechnik | Septum-Implantat |
| JP6410323B2 (ja) * | 2013-02-27 | 2018-10-24 | スピロックス, インク.Spirox, Inc. | 鼻インプラントを使用するシステム |
| CN103816002A (zh) * | 2014-03-06 | 2014-05-28 | 王震东 | 编织型镍钛合金鼻支架 |
| CN106572917B (zh) | 2014-06-20 | 2020-03-24 | 迅息Pty有限公司 | 鼻扩张器装置 |
| US20160287367A1 (en) | 2015-03-30 | 2016-10-06 | Daniel A. Rontal | Bioresorbable septoplasty closure implant |
| WO2017053824A1 (en) | 2015-09-25 | 2017-03-30 | Spirox, Inc. | Nasal implants and systems and method of use |
| CN106420111B (zh) * | 2016-11-24 | 2018-02-16 | 上海索康医用材料有限公司 | 一种永久植入型面部植入物及其制备方法 |
-
2018
- 2018-04-13 WO PCT/US2018/027560 patent/WO2018191659A1/en not_active Ceased
- 2018-04-13 US US16/604,490 patent/US11241306B2/en active Active
- 2018-04-13 CN CN201880038945.9A patent/CN110730642B/zh active Active
- 2018-04-13 EP EP18784113.5A patent/EP3609432B1/en active Active
- 2018-04-13 CN CN202210831437.4A patent/CN115192253A/zh active Pending
- 2018-04-13 JP JP2019555872A patent/JP7173986B2/ja active Active
- 2018-04-13 AU AU2018251992A patent/AU2018251992B2/en active Active
- 2018-04-13 CA CA3059439A patent/CA3059439A1/en active Pending
-
2021
- 2021-09-17 AU AU2021232798A patent/AU2021232798B2/en active Active
- 2021-12-28 US US17/564,200 patent/US12102525B2/en active Active
-
2022
- 2022-11-04 JP JP2022177378A patent/JP7569363B2/ja active Active
-
2024
- 2024-09-30 US US18/901,960 patent/US20250025292A1/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20070270899A1 (en) | 2006-05-17 | 2007-11-22 | Awengen Daniel | Implant for spreading the nasal wings |
| US20110251634A1 (en) | 2008-11-19 | 2011-10-13 | Gonzales Donald A | Apparatus and methods for correcting nasal valve collapse |
| WO2016033196A1 (en) | 2014-08-26 | 2016-03-03 | Spirox, Inc. | Nasal implants and systems and method of use |
Also Published As
| Publication number | Publication date |
|---|---|
| AU2021232798B2 (en) | 2023-07-06 |
| US12102525B2 (en) | 2024-10-01 |
| CN110730642B (zh) | 2022-07-29 |
| CN110730642A (zh) | 2020-01-24 |
| US20220117726A1 (en) | 2022-04-21 |
| JP2020516398A (ja) | 2020-06-11 |
| US11241306B2 (en) | 2022-02-08 |
| EP3609432B1 (en) | 2024-05-22 |
| EP3609432A4 (en) | 2020-12-02 |
| AU2018251992A1 (en) | 2019-10-31 |
| CA3059439A1 (en) | 2018-10-18 |
| JP2023022044A (ja) | 2023-02-14 |
| EP3609432A1 (en) | 2020-02-19 |
| CN115192253A (zh) | 2022-10-18 |
| JP7569363B2 (ja) | 2024-10-17 |
| AU2021232798A1 (en) | 2021-10-14 |
| US20200054446A1 (en) | 2020-02-20 |
| AU2018251992B2 (en) | 2021-06-17 |
| US20250025292A1 (en) | 2025-01-23 |
| WO2018191659A1 (en) | 2018-10-18 |
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