JP7161991B2 - 免疫レパートリーシーケンシングのための核酸サンプル調製の方法 - Google Patents

免疫レパートリーシーケンシングのための核酸サンプル調製の方法 Download PDF

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JP7161991B2
JP7161991B2 JP2019522907A JP2019522907A JP7161991B2 JP 7161991 B2 JP7161991 B2 JP 7161991B2 JP 2019522907 A JP2019522907 A JP 2019522907A JP 2019522907 A JP2019522907 A JP 2019522907A JP 7161991 B2 JP7161991 B2 JP 7161991B2
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nucleic acid
primer
adapter
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capture moiety
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ジェイソン マイヤーズ,
ジョシュア スタール,
ブレイディ カルバー,
ブライアン クドロー,
ジェンス エバーライン,
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アーチャーディーエックス, エルエルシー
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    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813Hybridisation assays
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
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    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2809Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against the T-cell receptor (TcR)-CD3 complex
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    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
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    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6806Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
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    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D495/00Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/32Fusion polypeptide fusions with soluble part of a cell surface receptor, "decoy receptors"
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    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6869Methods for sequencing

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  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
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JP2019522907A 2016-11-02 2017-11-02 免疫レパートリーシーケンシングのための核酸サンプル調製の方法 Active JP7161991B2 (ja)

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PCT/US2017/059804 WO2018085599A2 (en) 2016-11-02 2017-11-02 Methods of nucleic acid sample preparation for immune repertoire sequencing

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JP2022185155A (ja) 2022-12-13
WO2018085599A3 (en) 2018-06-07
EP4198140C0 (en) 2024-09-04
US20210180118A1 (en) 2021-06-17
EP4198140B1 (en) 2024-09-04
AU2023201370B2 (en) 2025-08-28
EP4198140A1 (en) 2023-06-21
US20180155767A1 (en) 2018-06-07
EP3535405A4 (en) 2020-07-15
CA3042391A1 (en) 2018-05-11
CN110191959A (zh) 2019-08-30
AU2023201370A1 (en) 2023-04-13
ES2940620T3 (es) 2023-05-09
CN110191959B (zh) 2024-04-09
WO2018085599A2 (en) 2018-05-11
AU2017355460B2 (en) 2022-12-08
US10947582B2 (en) 2021-03-16
EP3535405B1 (en) 2022-12-21
EP3535405A2 (en) 2019-09-11
AU2017355460A1 (en) 2019-05-23
JP7483824B2 (ja) 2024-05-15
JP2019537439A (ja) 2019-12-26

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