JP7138096B2 - 生物学的溶液中の単量体タンパク質から凝集タンパク質を分離するための方法 - Google Patents

生物学的溶液中の単量体タンパク質から凝集タンパク質を分離するための方法 Download PDF

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JP7138096B2
JP7138096B2 JP2019513416A JP2019513416A JP7138096B2 JP 7138096 B2 JP7138096 B2 JP 7138096B2 JP 2019513416 A JP2019513416 A JP 2019513416A JP 2019513416 A JP2019513416 A JP 2019513416A JP 7138096 B2 JP7138096 B2 JP 7138096B2
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solution
protein
acid
monomer
group
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JP2019536736A5 (enExample
JP2019536736A (ja
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アタン,セムラ コラク
ダブリュ. ヴェイル,アンドリュー
ケー. ラスムセン,ジェラルド
ダブリュ. グリースグラバー,ジョージ
エー. ボソフ,キャサリン
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3M Innovative Properties Co
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3M Innovative Properties Co
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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14Extraction; Separation; Purification
    • C07K1/34Extraction; Separation; Purification by filtration, ultrafiltration or reverse osmosis
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D71/00Semi-permeable membranes for separation processes or apparatus characterised by the material; Manufacturing processes specially adapted therefor
    • B01D71/06Organic material
    • B01D71/40Polymers of unsaturated acids or derivatives thereof, e.g. salts, amides, imides, nitriles, anhydrides, esters
    • B01D71/401Polymers based on the polymerisation of acrylic acid, e.g. polyacrylate
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14Extraction; Separation; Purification
    • C07K1/16Extraction; Separation; Purification by chromatography
    • C07K1/18Ion-exchange chromatography
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Water Supply & Treatment (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Peptides Or Proteins (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Enzymes And Modification Thereof (AREA)
JP2019513416A 2016-09-09 2017-08-30 生物学的溶液中の単量体タンパク質から凝集タンパク質を分離するための方法 Active JP7138096B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201662385385P 2016-09-09 2016-09-09
US62/385,385 2016-09-09
PCT/US2017/049376 WO2018048698A1 (en) 2016-09-09 2017-08-30 Processes for separating aggregated proteins from monomeric proteins in a biological solution

Publications (3)

Publication Number Publication Date
JP2019536736A JP2019536736A (ja) 2019-12-19
JP2019536736A5 JP2019536736A5 (enExample) 2020-10-22
JP7138096B2 true JP7138096B2 (ja) 2022-09-15

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JP2019513416A Active JP7138096B2 (ja) 2016-09-09 2017-08-30 生物学的溶液中の単量体タンパク質から凝集タンパク質を分離するための方法

Country Status (5)

Country Link
US (1) US20190194250A1 (enExample)
EP (1) EP3510041B1 (enExample)
JP (1) JP7138096B2 (enExample)
CN (1) CN109689674A (enExample)
WO (1) WO2018048698A1 (enExample)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3509729A1 (en) 2016-09-09 2019-07-17 3M Innovative Properties Company Functionalized copolymers and use thereof
WO2019123176A1 (en) 2017-12-20 2019-06-27 3M Innovative Properties Company Polymeric substrates with attached thiocarbonylthio-containing groups
EP3728425B1 (en) 2017-12-20 2021-12-08 3M Innovative Properties Company Polymeric substrates with attached polymeric chains
WO2020128732A2 (en) 2018-12-19 2020-06-25 3M Innovative Properties Company Zwitterionic copolymers, coating compositions, articles, and coating methods
JP2023521193A (ja) * 2020-04-13 2023-05-23 スリーエム イノベイティブ プロパティズ カンパニー フロースループロセス及び標的分子を精製するためのデバイス
EP4182377A1 (en) 2020-07-16 2023-05-24 3M Innovative Properties Company Phosphate-containing copolymers for virulence suppression
US20230302045A1 (en) * 2020-07-16 2023-09-28 3M Innovative Properties Company Phosphonate-containing polymers for virulence suppression
EP4573366A1 (en) * 2022-08-15 2025-06-25 Solventum Intellectual Properties Company Functionalized porous substrates and their use for detecting analytes

Citations (2)

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JP2013189427A (ja) 2012-03-12 2013-09-26 Emd Millipore Corp フロースルー式での生物製剤からのタンパク質凝集体の除去
WO2015050767A1 (en) 2013-10-03 2015-04-09 3M Innovative Properties Company Ligand-functionalized substrates with enhanced binding capacity

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US4707265A (en) 1981-12-18 1987-11-17 Cuno Incorporated Reinforced microporous membrane
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US5468847A (en) * 1994-03-10 1995-11-21 Minnesota Mining And Manufacturing Company Method of isolating and purifying a biomacromolecule
US5962544A (en) 1995-12-07 1999-10-05 3M Microporous materials of ethylene-vinyl alcohol copolymer and methods for making same
US6056529A (en) 1998-02-11 2000-05-02 Cuno, Inc. Systems for producing a plurality of different microporous phase inversion membrane each having any one of a plurality of different pore sizes from a single master dope batch
US6413070B1 (en) 1997-04-11 2002-07-02 Cuno Incorporated System for manufacturing reinforced three-zone microporous membrane
US6878419B2 (en) 2001-12-14 2005-04-12 3M Innovative Properties Co. Plasma treatment of porous materials
US7338692B2 (en) 2003-09-12 2008-03-04 3M Innovative Properties Company Microporous PVDF films
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US7674835B2 (en) 2005-12-21 2010-03-09 3M Innovative Properties Company Method of making macroporous anion exchange resins
US7683100B2 (en) 2005-12-21 2010-03-23 3M Innovative Properties Company Method of making macroporous cation exchange resins
US7674836B2 (en) * 2006-07-28 2010-03-09 3M Innovative Properties Company Method of making macroporous cation exchange resins
JP6062630B2 (ja) 2008-06-26 2017-01-18 スリーエム イノベイティブ プロパティズ カンパニー グラフト化鎖を伴う固体支持体
JP6141597B2 (ja) * 2009-02-27 2017-06-07 イー・エム・デイー・ミリポア・コーポレイシヨン タンパク質凝集物を除去するためのスルホン基を含有する膜
US9272246B2 (en) 2011-03-28 2016-03-01 3M Innovative Properties Company Ligand functional substrates
EP3326711B1 (en) 2012-06-05 2021-07-07 3M Innovative Properties Company Graft copolymer functionalized article
EP2901158B1 (en) 2012-09-27 2018-07-25 3M Innovative Properties Company Ligand grafted substrates
CN110054661A (zh) * 2013-12-12 2019-07-26 Emd密理博公司 使用含丙烯酰胺的过滤器分离蛋白
EP3509729A1 (en) * 2016-09-09 2019-07-17 3M Innovative Properties Company Functionalized copolymers and use thereof
FR3074575B1 (fr) * 2017-12-04 2020-10-16 Commissariat Energie Atomique Capteur de motif thermique a capacite pyroelectrique
WO2020128732A2 (en) * 2018-12-19 2020-06-25 3M Innovative Properties Company Zwitterionic copolymers, coating compositions, articles, and coating methods

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2013189427A (ja) 2012-03-12 2013-09-26 Emd Millipore Corp フロースルー式での生物製剤からのタンパク質凝集体の除去
WO2015050767A1 (en) 2013-10-03 2015-04-09 3M Innovative Properties Company Ligand-functionalized substrates with enhanced binding capacity

Also Published As

Publication number Publication date
US20190194250A1 (en) 2019-06-27
EP3510041A1 (en) 2019-07-17
WO2018048698A1 (en) 2018-03-15
EP3510041B1 (en) 2023-05-31
CN109689674A (zh) 2019-04-26
JP2019536736A (ja) 2019-12-19

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