JP7091244B2 - デオキシシチジンキナーゼ結合化合物 - Google Patents

デオキシシチジンキナーゼ結合化合物 Download PDF

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JP7091244B2
JP7091244B2 JP2018535341A JP2018535341A JP7091244B2 JP 7091244 B2 JP7091244 B2 JP 7091244B2 JP 2018535341 A JP2018535341 A JP 2018535341A JP 2018535341 A JP2018535341 A JP 2018535341A JP 7091244 B2 JP7091244 B2 JP 7091244B2
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JP2019504833A (ja
JP2019504833A5 (https=
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ラドゥ，カイウス・ジー
ギプソン，レイモンド・エム
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ザ・リージエンツ・オブ・ザ・ユニバーシテイー・オブ・カリフオルニア
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
JP2018535341A 2016-01-08 2017-01-09 デオキシシチジンキナーゼ結合化合物 Active JP7091244B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201662276546P 2016-01-08 2016-01-08
US62/276,546 2016-01-08
PCT/US2017/012718 WO2017120585A1 (en) 2016-01-08 2017-01-09 Deoxycytidine kinase binding compounds

Publications (3)

Publication Number Publication Date
JP2019504833A JP2019504833A (ja) 2019-02-21
JP2019504833A5 JP2019504833A5 (https=) 2020-02-20
JP7091244B2 true JP7091244B2 (ja) 2022-06-27

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ID=59274442

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JP2018535341A Active JP7091244B2 (ja) 2016-01-08 2017-01-09 デオキシシチジンキナーゼ結合化合物

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US (1) US10570124B2 (https=)
EP (1) EP3400224A4 (https=)
JP (1) JP7091244B2 (https=)
CN (1) CN108779111B (https=)
AU (1) AU2017205336A1 (https=)
CA (1) CA3010723A1 (https=)
WO (1) WO2017120585A1 (https=)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2016094307A1 (en) 2014-12-08 2016-06-16 The Research Foundation For The State University Of New York Anti-fungals targeting the synthesis of fungal shingolipids
WO2018232298A1 (en) 2017-06-16 2018-12-20 The Research Foundation For The State University Of New York Anti-fungals compounds targeting the synthesis of fungal sphingolipids
CN116723845A (zh) * 2020-11-02 2023-09-08 特雷西拉公司 脱氧胞苷激酶抑制剂的结晶形式及其用途
MX2023005056A (es) 2020-11-02 2023-07-24 Trethera Corp Formas cristalinas de un inhibidor de cinasa de desoxicitidina y sus usos.
US20250092032A1 (en) * 2022-01-17 2025-03-20 Centre National De La Recherche Scientifique Deoxycytidine kinase inhibitors
WO2024186827A2 (en) * 2023-03-06 2024-09-12 The Regents Of The University Of California Novel host-directed therapeutic agent for the treatment of infectious diseases

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2012122368A1 (en) 2011-03-08 2012-09-13 The Regents Of The University Of California Deoxycytidine kinase binding compounds

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2008302703B2 (en) 2007-09-19 2013-11-07 The Regents Of The University Of California Positron emission tomography probes for imaging immune activation and selected cancers
EA036177B1 (ru) * 2013-08-13 2020-10-09 Дзе Риджентс Оф Дзе Юниверсити Оф Калифорния Ингибиторы дезоксицитидинкиназы
US20190000850A1 (en) 2015-02-09 2019-01-03 The Regents Of The University Of California Combination cancer therapy

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2012122368A1 (en) 2011-03-08 2012-09-13 The Regents Of The University Of California Deoxycytidine kinase binding compounds

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Publication number Publication date
CA3010723A1 (en) 2017-07-13
WO2017120585A1 (en) 2017-07-13
US10570124B2 (en) 2020-02-25
AU2017205336A1 (en) 2018-07-26
EP3400224A4 (en) 2019-08-07
EP3400224A1 (en) 2018-11-14
CN108779111A (zh) 2018-11-09
US20190016714A1 (en) 2019-01-17
JP2019504833A (ja) 2019-02-21
CN108779111B (zh) 2021-11-12

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