JP7080899B2 - 同じヒト対象に由来する少なくとも２つの試料に対して早期バイオマーカーを使用する、外傷性脳損傷の超急性の診断及び決定の一助となるための方法 - Google Patents

同じヒト対象に由来する少なくとも２つの試料に対して早期バイオマーカーを使用する、外傷性脳損傷の超急性の診断及び決定の一助となるための方法 Download PDF

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JP7080899B2
JP7080899B2 JP2019556261A JP2019556261A JP7080899B2 JP 7080899 B2 JP7080899 B2 JP 7080899B2 JP 2019556261 A JP2019556261 A JP 2019556261A JP 2019556261 A JP2019556261 A JP 2019556261A JP 7080899 B2 JP7080899 B2 JP 7080899B2
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gfap
antibody
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マクイストン，ベス
ロジャーズ，ジャスティン
ダトワイラー，ソール
マリノ，ジェイミー
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    • G01N33/6896—Neurological disorders, e.g. Alzheimer's disease
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61B6/50—Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment specially adapted for specific body parts; specially adapted for specific clinical applications
    • A61B6/501—Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment specially adapted for specific body parts; specially adapted for specific clinical applications for diagnosis of the head, e.g. neuroimaging or craniography
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    • G01N2333/914—Hydrolases (3)
    • G01N2333/916—Hydrolases (3) acting on ester bonds (3.1), e.g. phosphatases (3.1.3), phospholipases C or phospholipases D (3.1.4)
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    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90—Enzymes; Proenzymes
    • G01N2333/914—Hydrolases (3)
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JP2019556261A 2017-04-28 2018-04-26 同じヒト対象に由来する少なくとも２つの試料に対して早期バイオマーカーを使用する、外傷性脳損傷の超急性の診断及び決定の一助となるための方法 Active JP7080899B2 (ja)

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US201762491600P 2017-04-28 2017-04-28
US62/491,600 2017-04-28
PCT/US2018/029585 WO2018200823A1 (en) 2017-04-28 2018-04-26 Methods for aiding in the hyperacute diagnosis and determination of traumatic brain injury using early biomarkers on at least two samples from the same human subject

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JP2020517919A JP2020517919A (ja) 2020-06-18
JP2020517919A5 JP2020517919A5 (https=) 2020-12-10
JP7080899B2 true JP7080899B2 (ja) 2022-06-06

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US (3) US10877038B2 (https=)
EP (1) EP3635407B1 (https=)
JP (1) JP7080899B2 (https=)
CN (1) CN110603449A (https=)
AU (1) AU2018256845B2 (https=)
BR (1) BR112019022476A2 (https=)
ES (1) ES3053676T3 (https=)
WO (1) WO2018200823A1 (https=)

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US12601749B2 (en) 2008-08-11 2026-04-14 Banyan Biomarkers, Inc. Biomarker detection process and assay of neurological condition
CA3261113A1 (en) * 2017-03-23 2025-10-27 Abbott Laboratories Methods for aiding in the diagnosis and determination of the extent of traumatic brain injury in a human subject using the early biomarker ubiquitin carboxy-terminal hydrolase l1
WO2018191531A1 (en) 2017-04-15 2018-10-18 Abbott Laboratories Methods for aiding in the hyperacute diagnosis and determination of traumatic brain injury in a human subject using early biomarkers
ES3053676T3 (en) 2017-04-28 2026-01-23 Abbott Lab Methods for aiding in the hyperacute diagnosis and determination of traumatic brain injury using early biomarkers on at least two samples from the same human subject
US10866251B2 (en) 2017-05-25 2020-12-15 Abbott Laboratories Methods for aiding in the determination of whether to perform imaging on a human subject who has sustained or may have sustained an injury to the head using early biomarkers
JP7269182B2 (ja) 2017-05-30 2023-05-08 アボット・ラボラトリーズ 心臓トロポニンｉ及び早期バイオマーカーを使用する、ヒト対象における軽度外傷性脳損傷を診断及び査定する一助となるための方法
US11169159B2 (en) 2017-07-03 2021-11-09 Abbott Laboratories Methods for measuring ubiquitin carboxy-terminal hydrolase L1 levels in blood
EP3721233A2 (en) * 2017-12-09 2020-10-14 Abbott Laboratories Methods for aiding in the diagnosis and evaluation of a subject who has sustained an orthopedic injury and that has or may have sustained an injury to the head, such as mild traumatic brain injury (tbi), using glial fibrillary acidic protein (gfap) and/or ubiquitin carboxy-terminal hydrolase l1 (uch-l1)
JP7379165B2 (ja) 2017-12-09 2023-11-14 アボット・ラボラトリーズ Ｇｆａｐとｕｃｈ－ｌ１との組合せを使用する、ヒト対象における外傷性脳損傷を診断及び査定する一助となるための方法
CN111699391A (zh) 2017-12-29 2020-09-22 雅培实验室 用于诊断和评估创伤性脑损伤的新型生物标志物和方法
US20220214362A1 (en) * 2019-05-10 2022-07-07 Abbott Laboratories Evaluating biomarkers along with advanced magnetic resonance imaging procedures in a human subject that has sustained or may have sustained a head injury
US20220381796A1 (en) * 2021-05-18 2022-12-01 Abbott Laboratories Methods of evaluating brain injury in a pediatric subject
WO2022266034A1 (en) * 2021-06-14 2022-12-22 Abbott Laboratories Methods of diagnosing or aiding in diagnosis of brain injury caused by acoustic energy, electromagnetic energy, an over pressurization wave, and/or blast wind
JP2024538608A (ja) * 2021-09-30 2024-10-23 アボット・ラボラトリーズ 脳の損傷を診断する方法及びシステム
CN113970643B (zh) * 2021-11-23 2023-06-30 北京大学人民医院 检测抗uch-l1表位的自身抗体的试剂在制备sle血清诊断相关产品中的应用
CN120167040A (zh) 2022-06-29 2025-06-17 雅培实验室 用于确定生物样本中的gfap的磁性定点照护型系统和测定
CN116646041B (zh) * 2023-07-21 2023-11-21 北京惠每云科技有限公司 基于大模型提升临床试验受试者匹配精度的方法和系统

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