JP7068743B2 - Ｍｇａｔ２阻害活性を有する縮合環誘導体を含有する医薬組成物 - Google Patents

Ｍｇａｔ２阻害活性を有する縮合環誘導体を含有する医薬組成物 Download PDF

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JP7068743B2
JP7068743B2 JP2020002515A JP2020002515A JP7068743B2 JP 7068743 B2 JP7068743 B2 JP 7068743B2 JP 2020002515 A JP2020002515 A JP 2020002515A JP 2020002515 A JP2020002515 A JP 2020002515A JP 7068743 B2 JP7068743 B2 JP 7068743B2
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substituted
unsubstituted
aromatic
aromatic heterocyclic
aromatic carbocyclic
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JP2020111571A (ja
JP2020111571A5 (enrdf_load_stackoverflow
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浩平 野津
佑介 舘野
健吾 枡田
祐二 西浦
義一 佐々木
優 日向
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Shionogi and Co Ltd
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JP2020002515A 2019-01-11 2020-01-10 Ｍｇａｔ２阻害活性を有する縮合環誘導体を含有する医薬組成物 Active JP7068743B2 (ja)

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JP2019003070 2019-01-11
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JP2020111571A5 JP2020111571A5 (enrdf_load_stackoverflow) 2022-03-04
JP7068743B2 true JP7068743B2 (ja) 2022-05-17

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CN114685502A (zh) * 2020-12-25 2022-07-01 由理生物医药（上海）有限公司 作为kras-g12c抑制剂的螺环类化合物
CN118215478A (zh) * 2021-09-08 2024-06-18 盐野义制药株式会社 用于预防和治疗与抗肥胖作用有关的疾病的药物
EP4475956A1 (en) 2022-02-09 2024-12-18 Quanta Therapeutics, Inc. Kras modulators and uses thereof
CN119604501A (zh) 2022-05-25 2025-03-11 光达治疗公司 基于嘧啶的调节剂及其用途

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2014009165A (ja) 2012-06-27 2014-01-20 Dainippon Sumitomo Pharma Co Ltd 二環性ピリミジン化合物
WO2014133134A1 (ja) 2013-02-28 2014-09-04 味の素株式会社 新規テトラヒドロピリドピリミジノン誘導体
WO2015134701A1 (en) 2014-03-07 2015-09-11 Bristol-Myers Squibb Company Dihydropyridinone mgat2 inhibitors for use in the treatment of metabolic disorders
WO2015144799A1 (en) 2014-03-27 2015-10-01 Janssen Pharmaceutica Nv SUBSTITUTED 4,5,6,7-TETRAHYDRO-PYRAZOLO[1,5-a]PYRAZINE DERIVATIVES AND 5,6,7,8-TETRAHYDRO-4H-PYRAZOLO[1,5-a][1,4]DIAZEPINE DERIVATIVES AS ROS1 INHIBITORS
WO2017069224A1 (ja) 2015-10-22 2017-04-27 塩野義製薬株式会社 Ｍｇａｔ２阻害活性を有するスピロ環誘導体
WO2019013312A1 (ja) 2017-07-14 2019-01-17 塩野義製薬株式会社 Ｍｇａｔ２阻害活性を有する縮合環誘導体

Patent Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2014009165A (ja) 2012-06-27 2014-01-20 Dainippon Sumitomo Pharma Co Ltd 二環性ピリミジン化合物
WO2014133134A1 (ja) 2013-02-28 2014-09-04 味の素株式会社 新規テトラヒドロピリドピリミジノン誘導体
WO2015134701A1 (en) 2014-03-07 2015-09-11 Bristol-Myers Squibb Company Dihydropyridinone mgat2 inhibitors for use in the treatment of metabolic disorders
WO2015144799A1 (en) 2014-03-27 2015-10-01 Janssen Pharmaceutica Nv SUBSTITUTED 4,5,6,7-TETRAHYDRO-PYRAZOLO[1,5-a]PYRAZINE DERIVATIVES AND 5,6,7,8-TETRAHYDRO-4H-PYRAZOLO[1,5-a][1,4]DIAZEPINE DERIVATIVES AS ROS1 INHIBITORS
WO2017069224A1 (ja) 2015-10-22 2017-04-27 塩野義製薬株式会社 Ｍｇａｔ２阻害活性を有するスピロ環誘導体
WO2019013312A1 (ja) 2017-07-14 2019-01-17 塩野義製薬株式会社 Ｍｇａｔ２阻害活性を有する縮合環誘導体
WO2019013311A1 (ja) 2017-07-14 2019-01-17 塩野義製薬株式会社 Ｍｇａｔ２阻害活性を有する縮合環誘導体
JP7060298B1 (ja) 2017-07-14 2022-04-26 塩野義製薬株式会社 Ｍｇａｔ２阻害活性を有する縮合環誘導体

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