JP7061568B2 - オピオイド新生児薬物離脱症候群の処置及び予防 - Google Patents

オピオイド新生児薬物離脱症候群の処置及び予防 Download PDF

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JP7061568B2
JP7061568B2 JP2018535324A JP2018535324A JP7061568B2 JP 7061568 B2 JP7061568 B2 JP 7061568B2 JP 2018535324 A JP2018535324 A JP 2018535324A JP 2018535324 A JP2018535324 A JP 2018535324A JP 7061568 B2 JP7061568 B2 JP 7061568B2
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pharmaceutical composition
opioid
drug
naltrexol
antagonist
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JP2019501194A (ja
JP2019501194A5 (https=
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ウォルフガング・サディー
ジョン・オーバーディック
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オハイオ・ステイト・イノベーション・ファウンデーション
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/485—Morphinan derivatives, e.g. morphine, codeine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4178—1,3-Diazoles not condensed 1,3-diazoles and containing further heterocyclic rings, e.g. pilocarpine, nitrofurantoin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/36—Opioid-abuse

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Addiction (AREA)
  • Emergency Medicine (AREA)
  • Organic Chemistry (AREA)
  • Psychiatry (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Saccharide Compounds (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
JP2018535324A 2016-01-08 2017-01-06 オピオイド新生児薬物離脱症候群の処置及び予防 Active JP7061568B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201662276691P 2016-01-08 2016-01-08
US62/276,691 2016-01-08
PCT/US2017/012452 WO2017120417A1 (en) 2016-01-08 2017-01-06 Treatments and prevention of opioid neonatal abstinence syndrome

Publications (3)

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JP2019501194A JP2019501194A (ja) 2019-01-17
JP2019501194A5 JP2019501194A5 (https=) 2020-01-23
JP7061568B2 true JP7061568B2 (ja) 2022-04-28

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JP2018535324A Active JP7061568B2 (ja) 2016-01-08 2017-01-06 オピオイド新生児薬物離脱症候群の処置及び予防

Country Status (8)

Country Link
US (3) US10925870B2 (https=)
EP (1) EP3400066B1 (https=)
JP (1) JP7061568B2 (https=)
CN (1) CN108778423A (https=)
AU (1) AU2017206041B2 (https=)
CA (1) CA3010609A1 (https=)
DK (1) DK3400066T3 (https=)
WO (1) WO2017120417A1 (https=)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2019199704A1 (en) * 2018-04-09 2019-10-17 Katana Pharmaceuticals, Inc. Oxytocin compositions and methods of use
CN113573711A (zh) * 2019-01-04 2021-10-29 伊瑟治疗公司 治疗药物或酒精依赖性的方法
US10653690B1 (en) * 2019-07-09 2020-05-19 Orexo Ab Pharmaceutical composition for nasal delivery
CN117915916A (zh) * 2021-07-06 2024-04-19 伊瑟治疗公司 低剂量纳曲醇和其用途
US11977085B1 (en) 2023-09-05 2024-05-07 Elan Ehrlich Date rape drug detection device and method of using same

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030069262A1 (en) 2000-03-15 2003-04-10 Wolfgang Sadee Neutral antagonists and use thereof in treating drug abuse
US20060111308A1 (en) 2004-11-16 2006-05-25 Wendye Robbins Methods and compositions for therapeutic treatment
US20060240085A1 (en) 2003-07-25 2006-10-26 Euro-Celtique S.A. Treatment of dependence withdrawal

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8748448B2 (en) 2007-10-18 2014-06-10 Aiko Biotechnology Combination analgesic employing opioid agonist and neutral antagonist
EP2214672B1 (en) 2007-10-18 2012-10-17 Aiko Biotechnology Combination analgesic employing opioid and neutral antagonist
WO2009079489A1 (en) * 2007-12-17 2009-06-25 The Ohio State University Research Foundation Methods for screening of opioid receptor neutral antagonists and inverse agonists and uses thereof
US9226918B2 (en) * 2008-12-04 2016-01-05 The Board Of Trustees Of The Leland Stanford Junior University Methods and compositions for treating or preventing narcotic withdrawal symptoms

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030069262A1 (en) 2000-03-15 2003-04-10 Wolfgang Sadee Neutral antagonists and use thereof in treating drug abuse
US20060240085A1 (en) 2003-07-25 2006-10-26 Euro-Celtique S.A. Treatment of dependence withdrawal
US20060111308A1 (en) 2004-11-16 2006-05-25 Wendye Robbins Methods and compositions for therapeutic treatment

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
ClinicalTrials.gov，2014年06月26日，NCT01965704
DEBELAK, Kimber et al.，The American Journal of Addictions，2013年，Vol. 22, Issue 3，pp. 252-254，https://doi.org/10.1111/j.1521-0391.2012.12005.x
ELKOMY, MH. et al.，CLINICAL PHARMACOLOGY & THERAPEUTICS，2015年02月，Vol. 97, No. 2，pp. 167-176，https://doi.org/10.1002/cpt.5
WIEGAND, Samantha L. et al.，OBSTETRICS & GYNECOLOGY，2015年02月，Vol. 125, Issue 2，pp. 363-368，https://doi.org/10.1097/AOG.0000000000000640

Also Published As

Publication number Publication date
JP2019501194A (ja) 2019-01-17
US20250177379A1 (en) 2025-06-05
CA3010609A1 (en) 2017-07-13
US12161641B2 (en) 2024-12-10
EP3400066A1 (en) 2018-11-14
EP3400066A4 (en) 2019-06-26
AU2017206041B2 (en) 2022-07-28
AU2017206041A1 (en) 2018-07-26
US10925870B2 (en) 2021-02-23
WO2017120417A1 (en) 2017-07-13
EP3400066B1 (en) 2021-07-28
DK3400066T3 (da) 2021-10-18
NZ744112A (en) 2025-05-30
US20190015406A1 (en) 2019-01-17
CN108778423A (zh) 2018-11-09
US20210205296A1 (en) 2021-07-08

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