JP7055638B2 - 幹細胞からの筋肉系列細胞の生成 - Google Patents
幹細胞からの筋肉系列細胞の生成 Download PDFInfo
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- JP7055638B2 JP7055638B2 JP2017555573A JP2017555573A JP7055638B2 JP 7055638 B2 JP7055638 B2 JP 7055638B2 JP 2017555573 A JP2017555573 A JP 2017555573A JP 2017555573 A JP2017555573 A JP 2017555573A JP 7055638 B2 JP7055638 B2 JP 7055638B2
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- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
- C12N5/0658—Skeletal muscle cells, e.g. myocytes, myotubes, myoblasts
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/34—Muscles; Smooth muscle cells; Heart; Cardiac stem cells; Myoblasts; Myocytes; Cardiomyocytes
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/04—Drugs for disorders of the muscular or neuromuscular system for myasthenia gravis
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- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
- C12N5/0658—Skeletal muscle cells, e.g. myocytes, myotubes, myoblasts
- C12N5/0659—Satellite cells
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/5044—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
- G01N33/5061—Muscle cells
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/48—Reproductive organs
- A61K35/54—Ovaries; Ova; Ovules; Embryos; Foetal cells; Germ cells
- A61K35/545—Embryonic stem cells; Pluripotent stem cells; Induced pluripotent stem cells; Uncharacterised stem cells
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- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/10—Growth factors
- C12N2501/15—Transforming growth factor beta (TGF-β)
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- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/40—Regulators of development
- C12N2501/415—Wnt; Frizzeled
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- C12N2510/00—Genetically modified cells
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- C12N2533/00—Supports or coatings for cell culture, characterised by material
- C12N2533/90—Substrates of biological origin, e.g. extracellular matrix, decellularised tissue
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Cell Biology (AREA)
- Biotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Rheumatology (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Developmental Biology & Embryology (AREA)
- Veterinary Medicine (AREA)
- General Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Molecular Biology (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Cardiology (AREA)
- Epidemiology (AREA)
- Virology (AREA)
- Vascular Medicine (AREA)
- Neurology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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- General Physics & Mathematics (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562151352P | 2015-04-22 | 2015-04-22 | |
| US62/151,352 | 2015-04-22 | ||
| PCT/AU2016/000144 WO2016168890A1 (en) | 2015-04-22 | 2016-04-22 | Generation of muscle-lineage cells from stem cells |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2018518943A JP2018518943A (ja) | 2018-07-19 |
| JP2018518943A5 JP2018518943A5 (OSRAM) | 2019-06-06 |
| JP7055638B2 true JP7055638B2 (ja) | 2022-04-18 |
Family
ID=60254709
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017555573A Expired - Fee Related JP7055638B2 (ja) | 2015-04-22 | 2016-04-22 | 幹細胞からの筋肉系列細胞の生成 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20180346879A1 (OSRAM) |
| EP (1) | EP3286301B1 (OSRAM) |
| JP (1) | JP7055638B2 (OSRAM) |
| CN (1) | CN107709545A (OSRAM) |
| AU (1) | AU2016250905B2 (OSRAM) |
| CA (1) | CA2983332A1 (OSRAM) |
| WO (1) | WO2016168890A1 (OSRAM) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL301900A (en) | 2014-11-21 | 2023-06-01 | Regeneron Pharma | Methods and compositions for targeted genetic modification using paired guide rnas |
| WO2017100498A1 (en) | 2015-12-11 | 2017-06-15 | The Johns Hopkins University | Isolation of fusion-competent myoblasts and therapeutic applications thereof related to muscular dystrophy |
| JP7090544B2 (ja) * | 2016-04-27 | 2022-06-24 | 武田薬品工業株式会社 | 骨格筋前駆細胞及び骨格筋細胞の製造方法 |
| JP7324583B2 (ja) | 2016-05-20 | 2023-08-10 | リジェネロン・ファーマシューティカルズ・インコーポレイテッド | 複数のガイドrnaを使用して免疫寛容を破綻させるための方法 |
| AU2017351638A1 (en) | 2016-10-26 | 2019-06-13 | Genea Biocells USA (Holdings), Inc. | Improved generation of muscle lineage cells and therapeutic uses thereof |
| US12365875B2 (en) | 2017-01-06 | 2025-07-22 | The Regents Of The University Of California | Methods for generating skeletal muscle progenitor cells |
| CN107937338B (zh) * | 2017-11-30 | 2021-08-03 | 中山大学 | 一种来自多能干细胞的中胚层谱系间充质干细胞及其制备方法 |
| CN110859854A (zh) * | 2018-08-08 | 2020-03-06 | 上海市东方医院 | 治疗神经源性肌肉萎缩的药物组合物及其制法和应用 |
| JP7033095B2 (ja) * | 2019-03-04 | 2022-03-09 | 日清食品ホールディングス株式会社 | 三次元筋組織とその製造方法 |
| US20220411825A1 (en) * | 2019-11-20 | 2022-12-29 | Vita Therapeutics, Inc. | Method of engineering hypoimmunogenic muscle precursor cells |
| JP7540893B2 (ja) * | 2020-02-27 | 2024-08-27 | テルモ株式会社 | Cd56陽性細胞の比率を高めるための組成物 |
| CN111826451A (zh) * | 2020-09-11 | 2020-10-27 | 中国肉类食品综合研究中心 | 实时荧光定量pcr检测猪肌肉调节因子的引物组及其应用 |
| WO2022093665A1 (en) * | 2020-10-26 | 2022-05-05 | University Of Massachusetts | Methods and compositions for treatment of muscle disease with ipsc-induced human skeletal muscle stem cells |
| WO2022140300A1 (en) * | 2020-12-22 | 2022-06-30 | Ixcells Biotechnolgies Usa, Inc. | Methods and compositions for differentiating skeletal muscle |
| US20240360415A1 (en) * | 2021-08-09 | 2024-10-31 | Aleph Farms Ltd. | Muscle cells differentiated from pluripotent cells, methods of producing same and use thereof |
| KR20240152443A (ko) * | 2023-04-12 | 2024-10-22 | 이엔셀 주식회사 | 근력 약화 관련 질환 치료제 스크리닝 방법 |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2013138623A1 (en) | 2012-03-14 | 2013-09-19 | Children's Medical Center Corporation | High-throughput image-based chemical screening in zebrafish blastomere cell culture |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5143842A (en) | 1988-11-01 | 1992-09-01 | The University Of Colorado Foundation, Inc. | Media for normal human muscle satellite cells |
| WO2007126077A1 (ja) * | 2006-04-28 | 2007-11-08 | Asubio Pharma Co., Ltd. | 多能性幹細胞から心筋細胞を分化誘導する方法 |
| AU2010355614B2 (en) * | 2010-06-13 | 2015-07-02 | Institute Of Biophysics, Chinese Academy Of Sciences | Methods and compositions for preparing cardiomyocytes from stem cells and uses thereof |
| WO2014015777A1 (zh) * | 2012-07-23 | 2014-01-30 | 中国科学院生物物理研究所 | 体外诱导多能干细胞分化为心室肌细胞的方法 |
| AU2014268197A1 (en) * | 2014-02-11 | 2015-08-27 | Monash University | Muscle cell production |
| CN104293730B (zh) * | 2014-09-23 | 2017-07-28 | 云南中科灵长类生物医学重点实验室 | 多能干细胞体外定向分化为心肌细胞的方法 |
| WO2016108288A1 (ja) * | 2014-12-29 | 2016-07-07 | 国立大学法人京都大学 | 骨格筋前駆細胞の製造方法 |
-
2016
- 2016-04-22 EP EP16782394.7A patent/EP3286301B1/en active Active
- 2016-04-22 CA CA2983332A patent/CA2983332A1/en active Pending
- 2016-04-22 CN CN201680035069.5A patent/CN107709545A/zh active Pending
- 2016-04-22 WO PCT/AU2016/000144 patent/WO2016168890A1/en not_active Ceased
- 2016-04-22 AU AU2016250905A patent/AU2016250905B2/en not_active Ceased
- 2016-04-22 US US15/568,274 patent/US20180346879A1/en not_active Abandoned
- 2016-04-22 JP JP2017555573A patent/JP7055638B2/ja not_active Expired - Fee Related
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2013138623A1 (en) | 2012-03-14 | 2013-09-19 | Children's Medical Center Corporation | High-throughput image-based chemical screening in zebrafish blastomere cell culture |
Non-Patent Citations (7)
| Title |
|---|
| Journal of Bone and Mineral Research, 2010, Vol.25, No.6, pp.1216-1233 |
| Methods, 2016, Vol.101, pp.73-84 |
| Nature Biotechnology, 2015, Vol.33, No.9, pp.962-969, ONLINE METHODS |
| Stem Cell Reports, 2013, Vol.1, pp.620-631 |
| Stem Cell Reports, 2014, Vol.2, pp.92-106 |
| Stem Cell Reports, 2014, Vol.3, pp.516-529 |
| Stem Cells, 2016, Vol.34, pp.299-310 |
Also Published As
| Publication number | Publication date |
|---|---|
| EP3286301B1 (en) | 2021-07-28 |
| AU2016250905B2 (en) | 2022-02-10 |
| WO2016168890A1 (en) | 2016-10-27 |
| JP2018518943A (ja) | 2018-07-19 |
| AU2016250905A8 (en) | 2018-03-15 |
| EP3286301A1 (en) | 2018-02-28 |
| AU2016250905A1 (en) | 2017-11-09 |
| EP3286301A4 (en) | 2019-02-20 |
| US20180346879A1 (en) | 2018-12-06 |
| CA2983332A1 (en) | 2016-10-27 |
| WO2016168890A8 (en) | 2017-11-30 |
| CN107709545A (zh) | 2018-02-16 |
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