JP7045330B2 - 生物学的及び非生物学的粒子を検知し分類するリアルタイム光学系方法及びシステム - Google Patents

生物学的及び非生物学的粒子を検知し分類するリアルタイム光学系方法及びシステム Download PDF

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JP7045330B2
JP7045330B2 JP2018556864A JP2018556864A JP7045330B2 JP 7045330 B2 JP7045330 B2 JP 7045330B2 JP 2018556864 A JP2018556864 A JP 2018556864A JP 2018556864 A JP2018556864 A JP 2018556864A JP 7045330 B2 JP7045330 B2 JP 7045330B2
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デビット ビー シルコット
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ハミルトン アソシエイツ インク
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/1434—Optical arrangements
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/02—Investigating particle size or size distribution
    • G01N15/0205—Investigating particle size or size distribution by optical means
    • G01N15/0211—Investigating a scatter or diffraction pattern
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/1429—Signal processing
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/1456—Optical investigation techniques, e.g. flow cytometry without spatial resolution of the texture or inner structure of the particle, e.g. processing of pulse signals
    • G01N15/1459—Optical investigation techniques, e.g. flow cytometry without spatial resolution of the texture or inner structure of the particle, e.g. processing of pulse signals the analysis being performed on a sample stream
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/01—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials specially adapted for biological cells, e.g. blood cells
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N2015/0042—Investigating dispersion of solids
    • G01N2015/0046—Investigating dispersion of solids in gas, e.g. smoke
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N2015/1006—Investigating individual particles for cytology
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/21—Polarisation-affecting properties
    • G01N2021/217—Measuring depolarisation or comparing polarised and depolarised parts of light

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  • Chemical & Material Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Engineering & Computer Science (AREA)
  • Signal Processing (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
JP2018556864A 2016-05-02 2017-04-11 生物学的及び非生物学的粒子を検知し分類するリアルタイム光学系方法及びシステム Active JP7045330B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US15/143,726 US9851291B2 (en) 2016-05-02 2016-05-02 Realtime optical method and system for detecting and classifying biological and non-biological particles
US15/143,726 2016-05-02
PCT/US2017/026933 WO2017192244A1 (en) 2016-05-02 2017-04-11 Realtime optical method and system for detecting and classifying biological and non-biological particles

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JP2019520551A JP2019520551A (ja) 2019-07-18
JP2019520551A5 JP2019520551A5 (https=) 2021-08-19
JP7045330B2 true JP7045330B2 (ja) 2022-03-31

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US (2) US9851291B2 (https=)
EP (1) EP3452801B1 (https=)
JP (1) JP7045330B2 (https=)
CN (1) CN109196330B (https=)
WO (1) WO2017192244A1 (https=)

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CN108287129A (zh) * 2018-03-22 2018-07-17 中国计量大学 多通道荧光谱生物气溶胶粒子的检测装置
DE102018006137A1 (de) * 2018-08-03 2020-02-06 Paragon Gmbh & Co. Kgaa Partikelmessvorrichtung und Verfahren zur Bestimmung der Partikelmassenkonzentrationen in Aerosolen
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JP2020176967A (ja) * 2019-04-22 2020-10-29 康嶺有限公司Ｈｅａｌｔｈ Ｐｅａｋ Ｌｉｍｉｔｅｄ 蛍光偏光を検出する光学系及び偏光度測定ユニット
CN111826422B (zh) * 2019-04-22 2024-03-26 康岭有限公司 检测荧光偏振的光学系统以及偏振度测量单元
RU192340U1 (ru) * 2019-05-13 2019-09-13 Федеральное государственное бюджетное образовательное учреждение высшего образования "Орловский государственный аграрный университет имени Н.В. Парахина" Датчик для определения микроорганизмов в воздухе
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CN110927025B (zh) * 2019-12-05 2023-03-10 北京华泰诺安探测技术有限公司 一种气溶胶粒子监测设备
CN111337392A (zh) * 2020-02-28 2020-06-26 清华大学深圳国际研究生院 一种悬浮颗粒偏振荧光同步测量装置
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CN113945490B (zh) * 2020-07-17 2025-05-02 航天神舟生物科技集团有限公司 一种激光粒子检测装置
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CN117392671B (zh) * 2023-10-26 2025-07-04 江苏大学 基于显微偏振图像特征的温室作物气传病害孢子分类方法
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CN118294428A (zh) * 2024-06-06 2024-07-05 浙江泰林分析仪器有限公司 一种基于激光诱导荧光技术的微生物检测光路
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