JP7035079B2 - 安定なプロテアーゼ変異型 - Google Patents

安定なプロテアーゼ変異型 Download PDF

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JP7035079B2
JP7035079B2 JP2019555724A JP2019555724A JP7035079B2 JP 7035079 B2 JP7035079 B2 JP 7035079B2 JP 2019555724 A JP2019555724 A JP 2019555724A JP 2019555724 A JP2019555724 A JP 2019555724A JP 7035079 B2 JP7035079 B2 JP 7035079B2
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protease variant
seq
kumamoricin
amino acid
variant according
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JP2020505944A (ja
JP2020505944A5 (enExample
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アンドレアス ミヒェルス
アンドレアス シャイディク
クリスティアン エレンド
クラウディア クラップ
トーマス ホルン
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イーダブル ニュートリション ゲゼルシャフト ミット ベシュレンクテル ハフツング
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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/48Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/52Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea
    • CCHEMISTRY; METALLURGY
    • C11ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11DDETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D3/00Other compounding ingredients of detergent compositions covered in group C11D1/00
    • C11D3/16Organic compounds
    • C11D3/38Products with no well-defined composition, e.g. natural products
    • C11D3/386Preparations containing enzymes, e.g. protease or amylase
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K20/00Accessory food factors for animal feeding-stuffs
    • A23K20/10Organic substances
    • A23K20/189Enzymes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/48Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/52Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea
    • C12N9/54Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea bacteria being Bacillus
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y304/00Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21Serine endopeptidases (3.4.21)

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Polymers & Plastics (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Food Science & Technology (AREA)
  • Animal Husbandry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Detergent Compositions (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Fodder In General (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
JP2019555724A 2016-12-22 2017-12-22 安定なプロテアーゼ変異型 Active JP7035079B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2022031591A JP7344329B2 (ja) 2016-12-22 2022-03-02 安定なプロテアーゼ変異型

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP16206367 2016-12-22
EP16206367.1 2016-12-22
PCT/EP2017/084452 WO2018115473A2 (en) 2016-12-22 2017-12-22 Stable protease variants

Related Child Applications (1)

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JP2020505944A JP2020505944A (ja) 2020-02-27
JP2020505944A5 JP2020505944A5 (enExample) 2021-02-04
JP7035079B2 true JP7035079B2 (ja) 2022-03-14

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JP2019555724A Active JP7035079B2 (ja) 2016-12-22 2017-12-22 安定なプロテアーゼ変異型
JP2022031591A Active JP7344329B2 (ja) 2016-12-22 2022-03-02 安定なプロテアーゼ変異型

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US (1) US11396648B2 (enExample)
EP (1) EP3559225A2 (enExample)
JP (2) JP7035079B2 (enExample)
KR (2) KR102686572B1 (enExample)
CN (1) CN110325636A (enExample)
AU (2) AU2017380106B2 (enExample)
BR (1) BR112019012980A2 (enExample)
CA (1) CA3047868A1 (enExample)
MX (2) MX2019007287A (enExample)
WO (1) WO2018115473A2 (enExample)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2021368118A1 (en) * 2020-10-30 2023-05-11 The Regents Of The University Of California Compositions and methods for treating celiac sprue disease
WO2023147350A1 (en) 2022-01-26 2023-08-03 Digestiva, Inc. Blood glucose stabilizing methods and compositions

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2013023151A2 (en) 2011-08-10 2013-02-14 University Of Washington Through Its Center For Commercialization Compositions and methods for treating celiac sprue disease
WO2015023728A1 (en) 2013-08-14 2015-02-19 University Of Washington Through Its Center For Commercialization Compositions and methods for treating celiac sprue disease
WO2016200880A1 (en) 2015-06-08 2016-12-15 University Of Washington Compositions and methods for treating celiac sprue disease
WO2017220776A1 (en) 2016-06-23 2017-12-28 Ew Nutrition Gmbh Feed composition comprising an acid protease

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1600141B1 (en) * 2004-05-24 2013-04-17 3M Deutschland GmbH Collagenolytic active enzyme containing compositions for the treatment of dental caries

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2013023151A2 (en) 2011-08-10 2013-02-14 University Of Washington Through Its Center For Commercialization Compositions and methods for treating celiac sprue disease
WO2015023728A1 (en) 2013-08-14 2015-02-19 University Of Washington Through Its Center For Commercialization Compositions and methods for treating celiac sprue disease
WO2016200880A1 (en) 2015-06-08 2016-12-15 University Of Washington Compositions and methods for treating celiac sprue disease
WO2017220776A1 (en) 2016-06-23 2017-12-28 Ew Nutrition Gmbh Feed composition comprising an acid protease

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
Kumamoliisin-As,Database UniProtKB/Swiss-Prot [online],2006年11月28日,Accession No. Q8GB88
Peptidase S53 propeptide,Database Uniprot [online],Accession No. J9HC20, entry version 19,2016年09月07日
TSURUOKA N. et al.,Appl. Environ. Microbiol.,2003年,Vol.69 No.1,p.162-169

Also Published As

Publication number Publication date
KR102553627B1 (ko) 2023-07-07
EP3559225A2 (en) 2019-10-30
JP2020505944A (ja) 2020-02-27
KR102686572B1 (ko) 2024-07-19
KR20230107898A (ko) 2023-07-18
BR112019012980A2 (pt) 2020-05-26
US11396648B2 (en) 2022-07-26
WO2018115473A3 (en) 2019-01-31
CA3047868A1 (en) 2018-06-28
JP7344329B2 (ja) 2023-09-13
JP2022081554A (ja) 2022-05-31
WO2018115473A2 (en) 2018-06-28
MX2019007287A (es) 2019-09-27
CN110325636A (zh) 2019-10-11
US20190322994A1 (en) 2019-10-24
AU2024202526A1 (en) 2024-05-30
AU2017380106B2 (en) 2024-05-09
MX2024000078A (es) 2024-02-23
KR20190095361A (ko) 2019-08-14
AU2017380106A1 (en) 2019-07-04

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