BR112019012980A2 - Variantes estáveis de protease - Google Patents
Variantes estáveis de protease Download PDFInfo
- Publication number
- BR112019012980A2 BR112019012980A2 BR112019012980-4A BR112019012980A BR112019012980A2 BR 112019012980 A2 BR112019012980 A2 BR 112019012980A2 BR 112019012980 A BR112019012980 A BR 112019012980A BR 112019012980 A2 BR112019012980 A2 BR 112019012980A2
- Authority
- BR
- Brazil
- Prior art keywords
- protease
- variant
- seq
- stable
- variables
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/52—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/52—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea
- C12N9/54—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea bacteria being Bacillus
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
- A23K20/189—Enzymes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
- C12Y304/21—Serine endopeptidases (3.4.21)
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
- C11D3/16—Organic compounds
- C11D3/38—Products with no well-defined composition, e.g. natural products
- C11D3/386—Preparations containing enzymes, e.g. protease or amylase
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Polymers & Plastics (AREA)
- Biomedical Technology (AREA)
- Medicinal Chemistry (AREA)
- Biotechnology (AREA)
- Molecular Biology (AREA)
- Microbiology (AREA)
- Food Science & Technology (AREA)
- Animal Husbandry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Enzymes And Modification Thereof (AREA)
- Detergent Compositions (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Fodder In General (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP16206367 | 2016-12-22 | ||
| EP16206367.1 | 2016-12-22 | ||
| PCT/EP2017/084452 WO2018115473A2 (en) | 2016-12-22 | 2017-12-22 | Stable protease variants |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR112019012980A2 true BR112019012980A2 (pt) | 2020-05-26 |
Family
ID=57629395
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR112019012980-4A BR112019012980A2 (pt) | 2016-12-22 | 2017-12-22 | Variantes estáveis de protease |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US11396648B2 (enExample) |
| EP (1) | EP3559225A2 (enExample) |
| JP (2) | JP7035079B2 (enExample) |
| KR (2) | KR102686572B1 (enExample) |
| CN (1) | CN110325636A (enExample) |
| AU (2) | AU2017380106B2 (enExample) |
| BR (1) | BR112019012980A2 (enExample) |
| CA (1) | CA3047868A1 (enExample) |
| MX (2) | MX2019007287A (enExample) |
| WO (1) | WO2018115473A2 (enExample) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2021368118A1 (en) * | 2020-10-30 | 2023-05-11 | The Regents Of The University Of California | Compositions and methods for treating celiac sprue disease |
| WO2023147350A1 (en) | 2022-01-26 | 2023-08-03 | Digestiva, Inc. | Blood glucose stabilizing methods and compositions |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1600141B1 (en) * | 2004-05-24 | 2013-04-17 | 3M Deutschland GmbH | Collagenolytic active enzyme containing compositions for the treatment of dental caries |
| HUE037870T2 (hu) | 2011-08-10 | 2018-09-28 | Univ Washington Through Its Center For Commercialization | Készítmények és módszerek lisztérzékenység kezelésére |
| EP3520808B1 (en) * | 2013-08-14 | 2021-04-21 | University Of Washington Through Its Center For Commercialization | Compositions for treating celiac sprue disease |
| BR112017026142A2 (pt) | 2015-06-08 | 2018-08-14 | Univ California | composições e métodos para tratar doença sprue celíaca |
| US20190230958A1 (en) * | 2016-06-23 | 2019-08-01 | Ew Nutrition Gmbh | Feed composition comprising an acid protease |
-
2017
- 2017-12-22 AU AU2017380106A patent/AU2017380106B2/en active Active
- 2017-12-22 CA CA3047868A patent/CA3047868A1/en active Pending
- 2017-12-22 US US16/471,507 patent/US11396648B2/en active Active
- 2017-12-22 KR KR1020237022708A patent/KR102686572B1/ko active Active
- 2017-12-22 WO PCT/EP2017/084452 patent/WO2018115473A2/en not_active Ceased
- 2017-12-22 BR BR112019012980-4A patent/BR112019012980A2/pt unknown
- 2017-12-22 JP JP2019555724A patent/JP7035079B2/ja active Active
- 2017-12-22 MX MX2019007287A patent/MX2019007287A/es unknown
- 2017-12-22 CN CN201780087051.4A patent/CN110325636A/zh active Pending
- 2017-12-22 KR KR1020197020123A patent/KR102553627B1/ko active Active
- 2017-12-22 EP EP17835479.1A patent/EP3559225A2/en active Pending
-
2019
- 2019-06-19 MX MX2024000078A patent/MX2024000078A/es unknown
-
2022
- 2022-03-02 JP JP2022031591A patent/JP7344329B2/ja active Active
-
2024
- 2024-04-17 AU AU2024202526A patent/AU2024202526A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| KR102553627B1 (ko) | 2023-07-07 |
| EP3559225A2 (en) | 2019-10-30 |
| JP7035079B2 (ja) | 2022-03-14 |
| JP2020505944A (ja) | 2020-02-27 |
| KR102686572B1 (ko) | 2024-07-19 |
| KR20230107898A (ko) | 2023-07-18 |
| US11396648B2 (en) | 2022-07-26 |
| WO2018115473A3 (en) | 2019-01-31 |
| CA3047868A1 (en) | 2018-06-28 |
| JP7344329B2 (ja) | 2023-09-13 |
| JP2022081554A (ja) | 2022-05-31 |
| WO2018115473A2 (en) | 2018-06-28 |
| MX2019007287A (es) | 2019-09-27 |
| CN110325636A (zh) | 2019-10-11 |
| US20190322994A1 (en) | 2019-10-24 |
| AU2024202526A1 (en) | 2024-05-30 |
| AU2017380106B2 (en) | 2024-05-09 |
| MX2024000078A (es) | 2024-02-23 |
| KR20190095361A (ko) | 2019-08-14 |
| AU2017380106A1 (en) | 2019-07-04 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| Chikate et al. | Differential protease activity augments polyphagy in H elicoverpa armigera | |
| Schneider et al. | Molecular mechanism of mast cell–mediated innate defense against endothelin and snake venom sarafotoxin | |
| Vioque et al. | Chemical and microbiological characteristics of ewes' milk cheese manufactured with extracts from flowers of Cynara cardunculus and Cynara humilis as coagulants | |
| Gogliettino et al. | Identification and characterisation of a novel acylpeptide hydrolase from Sulfolobus solfataricus: structural and functional insights | |
| Fu et al. | DegP functions as a critical protease for bacterial acid resistance | |
| Dong et al. | Cleavage‐dependent activation of a chlamydia‐secreted protease | |
| JP7344329B2 (ja) | 安定なプロテアーゼ変異型 | |
| Yang et al. | Substrate-induced changes in dynamics and molecular motions of cuticle-degrading serine protease PL646: a molecular dynamics study | |
| Elliott et al. | Functional identification of the cDNA coding for a wheat endo-1, 4-β-D-xylanase inhibitor | |
| Lu et al. | Dimerization and protease resistance: new insight into the function of PR-1 | |
| Wang et al. | Improving the catalytic activity of a detergent‐compatible serine protease by rational design | |
| Konarev et al. | Characterization of a glutenin-specific serine proteinase of Sunn bug Eurygaster integricepts Put. | |
| Lenz et al. | Pressure-based strategy for the inactivation of spores | |
| Adekoya et al. | Comparative sequence and structure analysis reveal features of cold adaptation of an enzyme in the thermolysin family | |
| Tremblay et al. | Harnessing the functional diversity of plant cystatins to design inhibitor variants highly active against herbivorous arthropod digestive proteases | |
| Alvarez-Alfageme et al. | Characterization of digestive enzymes of bruchid parasitoids–initial steps for environmental risk assessment of genetically modified legumes | |
| Hemmati et al. | Biochemical characterization and structural analysis of trypsin from P lodia interpunctella midgut: implication of determinants in extremely alkaline pH activity profile | |
| Chen et al. | Purification and characterization of a new rhizopuspepsin from Rhizopus oryzae NBRC 4749 | |
| US20230092791A1 (en) | Stable protease variants | |
| Park et al. | Chlorophyte aspartyl aminopeptidases: ancient origins, expanded families, new locations, and secondary functions | |
| Khajeh et al. | Acidic and proteolytic digestion of α-amylases from Bacillus licheniformis and Bacillus amyloliquefaciens: stability and flexibility analysis | |
| Liu et al. | Structural and dynamic basis of serine proteases from nematophagous fungi for cuticle degradation | |
| Li et al. | Site-directed mutagenesis of myofibril-bound serine proteinase from Crucian carp: possible role of Pro95, A127 and I130 on thermal stability | |
| Verbauwhede et al. | Heat‐sensitive inhibition of aqualysin 1 by protein containing wheat, maize, and barley extracts | |
| WO2015165472A2 (en) | Cold-active alpha-amylase |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B350 | Update of information on the portal [chapter 15.35 patent gazette] | ||
| B06W | Patent application suspended after preliminary examination (for patents with searches from other patent authorities) chapter 6.23 patent gazette] | ||
| B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] |