JP7011618B2 - Dissolved hydrogen water generator and dissolved hydrogen water generation method - Google Patents

Description

The present invention relates to a dissolved hydrogen water generator for producing dissolved hydrogen water used for preparing a dialysate and a method for producing dissolved hydrogen water.

In hemodialysis treatment, a dialysate prepared by using dissolved hydrogen water in which hydrogen is dissolved has been attracting attention in recent years as it contributes to reduction of oxidative stress in patients (see, for example, Patent Document 1).

Japanese Patent No. 5840248

In dialysis treatment using the device disclosed in Patent Document 1, it is unclear how much hydrogen is delivered to the patient's body, and a technique for controlling the production of dissolved hydrogen according to the hydrogen delivered to the body. Is desired to be established.

The present invention has been devised in view of the above circumstances, and provides a technique for controlling the production of dissolved hydrogen according to the hydrogen delivered to the body of a patient in hemodialysis treatment using dissolved hydrogen water. The main purpose is to do.

The first invention of the present invention is a dissolved hydrogen water generating apparatus for generating dissolved hydrogen water in which hydrogen is dissolved in water, and is prepared by a hydrogen water generating unit for generating the dissolved hydrogen water and the dissolved hydrogen water. A detection unit for detecting hydrogen gas contained in the blood of a patient undergoing dialysis using the dialysate, and a control for controlling the hydrogen water generation unit based on the detection result of the detection unit. It has a part.

In the production of the dissolved hydrogen water according to the present invention, the detector is returned to the patient from the first detector for detecting the amount of the hydrogen gas contained in the blood sent from the patient to the dialyzer and the dialyzer. It is desirable to include a second detector that detects the amount of the hydrogen gas contained in the blood.

In the dissolved hydrogen water generator according to the present invention, the control unit has the amount of the hydrogen gas detected by the second detector and the amount of the hydrogen gas detected by the first detector. It is desirable to control the hydrogen water generator based on the difference.

In the dissolved hydrogen water generation according to the present invention, it is desirable that the control unit controls the hydrogen water generation unit based on the average value of the differences.

In the dissolved hydrogen water generating apparatus according to the present invention, it is desirable that the control unit generates the dissolved hydrogen water based on the cumulative value of the difference.

In the generation of dissolved hydrogen water according to the present invention, it is desirable to further include a notification unit for notifying the amount or difference of the hydrogen gas.

In the dissolved hydrogen water generating apparatus according to the present invention, the hydrogen water generating unit includes an anode feeding body and a cathode feeding body for electrolyzing the water, and the control unit is the dissolved hydrogen of the dissolved hydrogen water. It is desirable to control the current for electrolysis supplied to the cathode feeder and the cathode feeder so that the concentration is increased or decreased.

In the dissolved hydrogen water generation according to the present invention, the hydrogen water generation unit includes an anodic feeding body and a cathode feeding body for electrolyzing the water, and the control unit has a threshold value for which the difference is predetermined. When it is smaller than, it is desirable that the control unit increases the current for electrolysis supplied to the anode feeder and the cathode feeder.

The second invention of the present invention is a method for producing dissolved hydrogen water in which hydrogen is dissolved in water, and is prepared by the production step of producing the dissolved hydrogen water and the dissolved hydrogen water. A detection step of detecting hydrogen gas contained in the blood of a patient undergoing dialysis using a dialysate and a control step of controlling the dissolved hydrogen concentration of the dissolved hydrogen water based on the detection result of the hydrogen gas. include.

In the dissolved hydrogen water generation method according to the present invention, the detection step includes a first detection step of detecting the amount of the hydrogen gas contained in the blood sent from the patient to the dialyzer, and a return from the dialyzer to the patient. The control step includes the second detection step of detecting the amount of the hydrogen gas contained in the blood, and the control step is based on the amount of the hydrogen gas detected by the second detection step and the first detection step. It is desirable to control the dissolved hydrogen concentration based on the difference between the detected amount of the hydrogen gas and the detected amount.

The dissolved hydrogen water generator of the first invention is the hydrogen water generation device based on the detection unit for detecting the hydrogen gas contained in the blood of the patient during dialysis and the detection result of the detection unit. The control unit for controlling the unit is provided. This makes it possible to appropriately control the production of the dissolved hydrogen water used in the preparation of the dialysate based on the hydrogen delivered into the body of the patient.

The method for producing dissolved hydrogen water according to the second invention is based on the detection step of detecting the hydrogen gas contained in the blood of a patient undergoing dialysis and the detection result of the hydrogen gas. It includes a control step of controlling the dissolved hydrogen concentration. This makes it possible to appropriately control the dissolved hydrogen concentration of the dissolved hydrogen water used for preparing the dialysate based on the hydrogen delivered to the patient's body.

It is a figure which shows the schematic structure of the dialysis system including the dissolved hydrogen water generation apparatus of this invention. It is a figure which shows the detection part of FIG. 1 in detail. It is a figure which shows the electrolytic cell which is an example of the hydrogen water generation part of FIG. It is a flowchart which shows the processing procedure of the dissolved hydrogen water generation method used for the dissolved hydrogen water generation apparatus of FIG. It is a flowchart which shows the processing procedure of the modification of the dissolved hydrogen water generation method of FIG. It is a flowchart which shows the processing procedure of another modification of the dissolved hydrogen water generation method of FIG. It is a flowchart which shows the processing procedure of the further modification of the dissolved hydrogen water generation method of FIG.

Hereinafter, embodiments of the present invention will be described with reference to the drawings.
FIG. 1 shows a schematic configuration of a dialysis system 100 including the dissolved hydrogen water generator 1 of the present embodiment. The dissolved hydrogen water generator 1 is an apparatus for generating dissolved hydrogen water in the dialysis system 100 in which the dialysate prepared by the dissolved hydrogen water generation is used.

The dialysis system 100 includes a reverse osmosis membrane treatment device 2, a dissolved hydrogen water generation device 1, a dialysate preparation device 5, and a dialysis device 6.

The reverse osmosis membrane treatment device 2 purifies the raw water by the reverse osmosis treatment and supplies it to the dissolved hydrogen water generation device 1. Tap water is generally used as the raw water, but other water such as well water and groundwater can also be used.

The reverse osmosis membrane treatment device 2 includes a water softening treatment device 21, an activated carbon treatment device 22, and a reverse osmosis membrane module 23. The water softening treatment device 21 removes hardness components such as calcium ions and magnesium ions from the raw water to soften the water. The activated carbon treatment device 22 has activated carbon which is a fine porous substance, and adsorbs and removes chlorine and the like from the water supplied from the water softening treatment device 21. The reverse osmosis membrane module 23 separates the water supplied from the activated carbon treatment apparatus 22 into treated water purified by the reverse osmosis membrane and concentrated water containing impurities. The treated water purified by the reverse osmosis membrane module 23 is sent to the dissolved hydrogen water generator 1. On the other hand, the concentrated water that could not permeate the reverse osmosis membrane is discharged to the outside of the reverse osmosis membrane treatment device 2.

The dissolved hydrogen water generation device 1 adds hydrogen to the water purified by the reverse osmosis membrane treatment device 2 to generate dissolved hydrogen water. The dissolved hydrogen water generation device 1 includes a hydrogen water generation unit 3 for generating dissolved hydrogen water (hydrogen-containing water) in which hydrogen gas is dissolved. In this embodiment, the electrolytic cell 4 is applied as a part of the hydrogen water generation unit 3. The details of the electrolytic cell 4 will be described later. The dissolved hydrogen water generated by the hydrogen water generation unit 3 is sent to the dialysate preparation device 5 as dialysate preparation water.

The dialysate preparation device 5 prepares a dialysate by, for example, diluting a liquid dialysate using the dialysate preparation water supplied from the hydrogen water generation unit 3. The dialysate prepared by the dialysate preparation device 5 is sent to the dialysate device 6.

The dialysis machine 6 includes a dialysate supply device 61 and a dialyzer 62. The dialysate supply device 61 sends the dialysate supplied from the dialysate preparation device 5 to the dialyzer 62. The dialyzer 62 is an artificial kidney containing, for example, a dialysis membrane 62a composed of a porous membrane such as a hollow yarn membrane, and receives dialysis treatment from the dialysate supplied from the dialysate preparation device 5 via the dialysis membrane 62a. It acts on the blood of patient H to remove waste products and water from the blood.

The patient H and the dialyzer 62 are connected to each other via blood circuits 63 and 64. The blood circuit 63 sends the blood collected from the patient H to the dialyzer 62. The blood circuit 63 is provided with a pump 65 for pumping blood. The blood circuit 64 returns the blood from which waste products and the like have been removed by the dialyzer 62 to the patient H.

The dissolved hydrogen water generation device 1 includes a detection unit 12 for detecting hydrogen gas contained in the blood of patient H, and a control unit 13 for controlling the hydrogen water generation unit 3.

The detection unit 12 collects the blood of the patient H, detects the amount of hydrogen gas per unit volume of the blood, and outputs the corresponding electric signal to the control unit 13. A known hydrogen gas detector or the like can be applied to the detection unit 12. The detection unit 12 of the present embodiment is provided in the blood circuits 63 and 64, and detects hydrogen gas contained in the blood flowing through the blood circuits 63 and 64. A part of the blood flowing through the blood circuits 63 and 64 may be configured to be supplied to the detection unit 12.

The control unit 13 is composed of, for example, a CPU (Central Processing Unit) that executes various arithmetic processes, information processing, and the like, a program that controls the operation of the CPU, a memory that stores various information, and the like. The control unit 13 controls each unit of the dissolved hydrogen water generation device 1.

More specifically, the control unit 13 controls the hydrogen water generation unit 3 based on the electric signal input from the detection unit 12, that is, the detection result of the detection unit 12. For example, when hydrogen gas is detected in the blood of patient H, it is confirmed that the hydrogen added in the hydrogen water generation unit 3 surely reaches and is absorbed in the body of patient H via the dialysate and blood. Therefore, the operation of the hydrogen water generation unit 3 is weakened or stopped.

On the other hand, when hydrogen gas is not detected in the blood of patient H, it can be confirmed that hydrogen has not yet reached the body of patient H. Therefore, for example, the operation of the hydrogen water generation unit 3, that is, the generation of dissolved hydrogen water is continued. .. In this case, the control unit 13 may control the operation of the hydrogen water generation unit 3 so as to increase the dissolved hydrogen concentration.

Therefore, according to the dissolved hydrogen water generation device 1, it is possible to appropriately control the generation of the dissolved hydrogen water used for preparing the dialysate based on the hydrogen delivered to the body of the patient H.

FIG. 2 shows the detection unit 12. The detection unit 12 includes a first detector 12a and a second detector 12b that detect the amount of hydrogen gas contained in blood.

The first detector 12a and the second detector 12b collect blood flowing through the blood circuits 63 and 64 and detect the amount of hydrogen gas contained in the blood. More specifically, the first detector 12a is provided in the blood circuit 63 and detects the amount of hydrogen gas per unit volume of blood sent from the patient H to the dialyzer 62. The second detector 12b is provided in the blood circuit 64 and detects the amount of hydrogen gas per unit volume of blood returned from the dialyzer 62 to the patient H. The detection unit 12 outputs an electric signal corresponding to the amount of hydrogen gas detected by the first detector 12a and the second detector 12b to the control unit 13. As a result, the control unit 13 can individually know the amount of hydrogen gas contained in the blood flowing through the blood circuits 63 and 64 and can use it for controlling the hydrogen water generation unit 3.

For example, if the amount of hydrogen gas detected by the second detector 12b is greater than the amount of hydrogen gas detected by the first detector 12a, it is considered that the hydrogen gas in the blood has been absorbed by the patient H. Therefore, the control unit 13 calculates the difference between the amount of hydrogen gas detected by the second detector 12b and the amount of hydrogen gas detected by the first detector 12a, so that the hydrogen absorbed by the patient H can be calculated. The amount of gas can be known and can be used for controlling the hydrogen water generation unit 3.

For example, the control unit 13 appropriately controls the hydrogen water generation unit 3 by calculating the difference in the amount of hydrogen gas and comparing it with a predetermined first threshold value. The first threshold value can be determined, for example, by statistically processing information regarding the transition of the symptom of patient H (hereinafter, the same applies to the second threshold value to the sixth threshold value). With such a configuration, it becomes possible to appropriately control the hydrogen water generation unit 3 based on the amount of hydrogen gas absorbed by the patient H.

The amount of the hydrogen gas may be a volume, a molecular weight, or the like, in addition to the mass. Further, the control unit 13 may be configured to calculate the amount of hydrogen gas absorbed by the patient H in a unit time.

Further, in the present dissolved hydrogen water generation device 1, the control unit 13 may be configured to control the hydrogen water generation unit 3 based on the average value of the difference in the amount of hydrogen gas. For example, the control unit 13 controls the hydrogen water generation unit 3 by calculating an average value of the difference in the amount of hydrogen gas and comparing it with a predetermined second threshold value. It is desirable that the control unit 13 calculates the moving average value at regular time intervals as the average value. With such a configuration, it is possible to appropriately control the hydrogen water generation unit 3 without being affected by minute fluctuations in the concentration of hydrogen gas in the blood.

Further, in the present dissolved hydrogen water generation device 1, the control unit 13 may be configured to control the hydrogen water generation unit 3 based on the cumulative value of the difference in the amount of hydrogen gas. For example, the control unit 13 controls the hydrogen water generation unit 3 by calculating the cumulative value of the difference in the amount of hydrogen gas by the detection unit 12 and comparing it with a predetermined third threshold value. With such a configuration, it becomes possible to appropriately control the hydrogen water generation unit 3 based on the hydrogen gas accumulated in the body of the patient H.

It is desirable that the dissolved hydrogen water generator 1 further includes a notification unit 14 for notifying the amount or difference of the hydrogen gas. For example, an LED that outputs an optical signal, a speaker device that outputs an audio signal, or the like is applied to the notification unit 14. The notification may be a combination of an optical signal and an audio signal. The operation of the notification unit 14 is controlled by, for example, the control unit 13. By providing the notification unit 14 in the dissolved hydrogen water generation device 1, the doctor, the nurse, or the patient H can know that hydrogen has reached the body of the patient H by the notification unit 14.

FIG. 3 shows an electrolytic cell 4 constituting the hydrogen water generation unit 3. The electrolytic cell 4 generates hydrogen molecules by electrolyzing water. When these hydrogen molecules dissolve in water, dissolved hydrogen water, which is water to which the first hydrogen is added, is generated.

The electrolytic cell 4 includes an electrolytic cell 40, and has a first feeding body 41 and a second feeding body 42 in the electrolytic cell 40. The first feeding body 41 and the second feeding body 42 are provided in the electrolytic chamber 40.

A diaphragm 43 is provided between the first feeding body 41 and the second feeding body 42. The electrolytic chamber 40 is divided into a first pole chamber 40a in which the first feeding body 41 is arranged and a second pole chamber 40b in which the second feeding body 42 is arranged by the diaphragm 43.

The polarities of the first feeding body 41 and the second feeding body 42 and the voltage applied to the first feeding body 41 and the second feeding body 42 are controlled by the control unit 13.

A current detector is provided in the current supply line between the feeding bodies 41 and 42 and the control unit 13. The current detector detects the electrolytic current supplied to the first feeding body 41 and the second feeding body 42, and outputs an electric signal corresponding to the value to the control unit 13.

The control unit 13 controls the DC voltage applied to the first feeding body 41 and the second feeding body 42, for example, based on the electric signal output from the current detector. More specifically, the control unit 13 applies a DC voltage to the first feeding body 41 and the second feeding body 42 so that the electrolytic current detected by the current detector becomes a preset desired value. Feedback control. For example, when the electrolytic current is excessive, the control unit 13 decreases the voltage, and when the electrolytic current is too small, the control unit 13 increases the voltage. As a result, the electrolytic current supplied to the first feeding body 41 and the second feeding body 42 is appropriately controlled.

Hydrogen gas and oxygen gas are generated by electrolyzing water in the electrolytic chamber 40. For example, in the second polar chamber 40b on the cathode side, hydrogen gas is generated, and dissolved hydrogen water in which the hydrogen molecules are dissolved is generated and supplied to the reverse osmosis membrane module 23 of the reverse osmosis membrane treatment device 2. The dissolved hydrogen water generated by such electrolysis is also referred to as "electrolyzed hydrogen water", and the dialysis treatment using the electrolytic hydrogen water is also referred to as "electrolyzed water dialysis". On the other hand, oxygen gas is generated in the first pole chamber 40a on the anode side.

For the diaphragm 43, for example, a solid polymer membrane made of a fluororesin having a sulfonic acid group is appropriately used. In the solid polymer membrane, the oxonium ion generated in the first pole chamber 40a on the anode side is moved to the second pole chamber 40b on the cathode side by electrolysis, and is used as a raw material for producing hydrogen gas. Therefore, the pH of the dissolved hydrogen water does not change without generating hydroxide ions during electrolysis.

In the present embodiment, the control unit 13 increases or decreases the dissolved hydrogen concentration of the dissolved hydrogen water based on the difference in the amount of hydrogen gas detected by the detection unit 12, so that the first feeder 41 and the second feeder 41 and the second It is desirable that it is configured to control the current for electrolysis supplied to the feeder 42.

More specifically, when the difference in the amount of hydrogen gas detected by the detection unit 12 is smaller than a predetermined threshold value, the control unit 13 supplies electricity to the first power supply body 41 and the second power supply body 42. Greatly control the current for decomposition. On the other hand, when the amount of the hydrogen gas is larger than a predetermined threshold value, the control unit 13 may control the current for electrolysis supplied to the first feeding body 41 and the second feeding body 42 to be small. ..

Further, when the average value or the cumulative value of the amount of the hydrogen gas detected by the detection unit 12 is smaller than a predetermined threshold value, the control unit 13 supplies the first power supply body 41 and the second power supply body 42. It may be configured to largely control the current for electrolysis. On the other hand, when the average value or the cumulative value of the amount of hydrogen gas is larger than a predetermined threshold value, the control unit 13 applies a current for electrolysis to be supplied to the first feeding body 41 and the second feeding body 42. It may be controlled small.

Further, the control unit 13 determines the current for electrolysis supplied to the first feeding body 41 and the second feeding body 42 based on the combination of the average value and the cumulative value of the amount of hydrogen gas per unit volume of exhaled breath. It may be configured to be largely controlled.

FIG. 4 shows a treatment procedure of the dissolved hydrogen water generation method 500 used in the present dissolved hydrogen water generation device 1. The dissolved hydrogen water generation method 500 is repeatedly executed during dialysis treatment using a dialysate to which hydrogen is added, and includes a generation step S1, a detection step S21, S22, and a control step S3, S4, S5. There is.

In the generation step S1, dissolved hydrogen water is generated by the hydrogen water generation unit 3. The production of dissolved hydrogen water is, in principle, continued during the dialysis treatment.

In the detection step S21, the blood of patient H undergoing dialysis is collected. In the present dissolved hydrogen water generation device 1, the detection step S21 is executed by the detection unit 12. In the detection step S22, the detection unit 12 detects the hydrogen gas contained in the blood collected in the detection step S21. In the control steps S3, S4, and S5, the control unit 13 controls the hydrogen water generation unit 3 based on the detection result in the detection step S2. For example, when hydrogen gas is detected in the blood (Y in S3), it can be determined that the hydrogen gas has reached the body of the patient H, so that the operation of the hydrogen water generation unit 3 is weakened or stopped (S4). For example, in the control step S4, the control unit 13 weakens or cuts off the current for electrolysis.

On the other hand, when hydrogen gas is not detected in the blood (N in S3), the operation of the hydrogen water generation unit 3 is controlled so as to increase the dissolved hydrogen concentration (S5), and the process returns to S21. For example, in the control step S5, the control unit 13 increases the current for electrolysis.

According to the present dissolved hydrogen water generation method 500, it is possible to appropriately control the production of dissolved hydrogen water used for preparing a dialysate based on the hydrogen delivered to the body of the patient H.

FIG. 5 shows a dissolved hydrogen water generation method 500A which is a modification of the dissolved hydrogen water generation method 500 of FIG. The treatment procedure of the above-mentioned dissolved hydrogen water generation method 500 can be adopted for the portion of the dissolved hydrogen water generation method 500A not described below.

In the dissolved hydrogen water generation method 500A, the detection steps S23, S24, S25 and S26 are applied instead of the detection steps S21 and S22 of the dissolved hydrogen water generation method 500, and the control steps S31 and S32 are replaced with the control step S3. Applies.

In the detection step S23, the blood sent from the patient H to the dialyzer 62 is collected by the first detector 12a provided in the blood circuit 63. In the detection step S24, the blood returned from the dialyzer 62 to the patient H is collected by the second detector 12b provided in the blood circuit 64.

In the detection step S25, the amount of hydrogen gas contained in the blood collected in the detection step S23 is detected. As a result, the amount of hydrogen gas contained in the blood sent from the patient H to the dialyzer 62 is detected. In the detection step S26, the amount of hydrogen gas contained in the blood collected in the detection step S24 is detected. As a result, the amount of hydrogen gas contained in the blood returned from the dialyzer 62 to the patient H is detected.

In the control step S31, the difference between the amount of hydrogen gas detected in the detection step S26 and the amount of hydrogen gas detected in the detection step S25 is calculated. That is, the control unit 13 calculates the difference in the amount of hydrogen gas by subtracting the amount of hydrogen gas detected in the detection step S25 from the amount of hydrogen gas detected in the detection step S26. The difference in the amount of hydrogen gas can be considered as the amount of hydrogen gas absorbed by the patient H.

In the control step S32, the difference in the amount of the hydrogen gas calculated in the control step S31 is compared with the first threshold value. When the difference in the amount of hydrogen gas is equal to or greater than the first threshold value (Y in S32), the process proceeds to S4. It may be configured to return to S21 after executing S4.

On the other hand, when the difference in the amount of hydrogen gas is smaller than the first threshold value (N in S32), the process shifts to S5 and then returns to S21. In the dissolved hydrogen water generation method 500A, the control unit 13 controls the operation of the hydrogen water generation unit 3 based on the amount of hydrogen gas absorbed by the patient H by calculating the difference from the amount of the hydrogen gas. , It becomes possible to appropriately control the production of dissolved hydrogen water used for the preparation of dialysate.

FIG. 6 shows a dissolved hydrogen water generation method 500B which is a modification of the dissolved hydrogen water generation method 500A of FIG. For the portion of the dissolved hydrogen water generation method 500B that is not described below, the treatment procedure of the above-mentioned dissolved hydrogen water generation method 500A or the like can be adopted.

In the dissolved hydrogen water generation method 500B, the control steps S33 and S34 are applied instead of the control steps S31 and S32 of the dissolved hydrogen water generation method 500A. In the control steps S33, S34, S4, and S5, the control unit 13 calculates the average value of the difference in the amount of hydrogen gas based on the detection results in the detection steps S25 and S26, and operates the hydrogen water generation unit 3. To control.

That is, in the control step S33, the control unit 13 calculates the average value of the difference in the amounts of the hydrogen gas based on the detection results in the detection steps S25 and S26. Then, when the average value of the amount of hydrogen gas is equal to or higher than the second threshold value (Y in S34), the process proceeds to S4. On the other hand, when the average value of the amount of hydrogen gas is smaller than the second threshold value (N in S34), the process shifts to S5 and then returns to S21. In the dissolved hydrogen water generation method 500B, the operation of the hydrogen water generation unit 3 is controlled based on the average value of the hydrogen gas concentration in the exhaled breath, so that it is affected by minute fluctuations in the hydrogen gas concentration in the exhaled breath. Instead, it is possible to appropriately control the production of dissolved hydrogen water used in the preparation of dialysate.

FIG. 7 shows a dissolved hydrogen water generation method 500C, which is another modification of the dissolved hydrogen water generation method 500A of FIG. The treatment procedure of the above-mentioned dissolved hydrogen water generation method 500 can be adopted for the portion of the dissolved hydrogen water generation method 500C which is not described below.

In the dissolved hydrogen water generation method 500C, the control steps S35 and S36 are applied instead of the control steps S31 and S32 of the dissolved hydrogen water generation method 500A. In the control steps S35, S36, S4, and S5, the control unit 13 calculates the cumulative value of the difference in the amount of hydrogen gas based on the detection results in the detection steps S25 and S26, and operates the hydrogen water generation unit 3. To control.

That is, in the control step S31, the control unit 13 calculates the cumulative value of the difference in the amount of the detected hydrogen gas based on the detection results in the detection steps S25 and S26. Then, when the cumulative value of the difference in the amount of hydrogen gas is equal to or higher than the third threshold value (Y in S35), the process proceeds to S4. .. On the other hand, when the cumulative value of the amount of hydrogen gas is smaller than the first threshold value (N in S36), the process shifts to S5 and then returns to S21. In the dissolved hydrogen water generation method 500C, the operation of the hydrogen water generation unit 3 is controlled based on the cumulative value of the difference in the amount of hydrogen gas, so that the dialysate is charged according to the hydrogen gas accumulated in the body of the patient H. It is possible to appropriately control the production of dissolved hydrogen water used in the preparation.

Although the dissolved hydrogen water generation device 1 of the present invention has been described in detail above, the present invention is not limited to the above-mentioned specific embodiment, but is modified to various embodiments. That is, the present dissolved hydrogen water generating apparatus 1 is at least an apparatus for generating dissolved hydrogen water in which hydrogen is dissolved in water, and is prepared by a hydrogen water generating unit 3 for generating dissolved hydrogen water and dissolved hydrogen water. To control the hydrogen water generation unit 3 based on the detection unit 12 for detecting the hydrogen gas contained in the blood of the patient H undergoing dialysis using the dialysate and the detection result of the detection unit 12. It suffices to include the control unit 13 of the above.

Therefore, for example, even if the control unit 13 is configured to determine that dialysis is completed when the difference in the amount of hydrogen gas or the average value exceeds a predetermined fourth threshold value or fifth threshold value. good. Further, the control unit 13 may be configured to determine that dialysis has been completed when the cumulative value exceeds a predetermined sixth threshold value.

Further, the hydrogen water generation unit 3 is not limited to the electrolytic tank 4 that generates dissolved hydrogen water by electrolyzing water, and for example, hydrogen molecules generated by a chemical reaction between water and magnesium are dissolved in water. It may be an apparatus for generating dissolved hydrogen water or an apparatus for generating dissolved hydrogen water by dissolving hydrogen gas (hydrogen molecule) supplied from a hydrogen gas cylinder in water.

Further, the present dissolved hydrogen water generation method 500 or the like is at least a method for generating dissolved hydrogen water in which hydrogen is dissolved in water, and is prepared by the generation step S1 for producing the dissolved hydrogen water and the dissolved hydrogen water. A detection step S22 for detecting hydrogen gas contained in the blood of patient H undergoing dialysis using the dialysate, and a control step S3 for controlling the dissolved hydrogen concentration of the dissolved hydrogen water based on the detection result of the hydrogen gas. Or S5 may be included.

1 Dissolved hydrogen water generation device 3 Hydrogen water generation unit 12 Detection unit 13 Control unit 14 Notification unit 500 Dissolved hydrogen water generation method 500A Dissolved hydrogen water generation method 500B Dissolved hydrogen water generation method 500C Dissolved hydrogen water generation method S2 Detection step S21 Detection step S22 Detection step S3 Control step S31 Control step S32 Control step S4 Control step S5 Control step H Patient

Claims (4)

It is a device for generating dissolved hydrogen water in which hydrogen is dissolved in water.
The hydrogen water generation unit that generates the dissolved hydrogen water,
A detection unit for detecting hydrogen gas contained in the blood of a patient undergoing dialysis using a dialysate prepared from the dissolved hydrogen water, and a detection unit.
A control unit for controlling the hydrogen water generation unit is provided based on the detection result of the detection unit .
The detection unit has a first detector that detects the amount of the hydrogen gas contained in the blood sent from the patient to the dialyzer, and the amount of the hydrogen gas contained in the blood returned from the dialyzer to the patient. Including a second detector to detect
The control unit is based on the cumulative value of the difference between the amount of the hydrogen gas detected by the second detector and the amount of the hydrogen gas detected by the first detector. To generate,
Dissolved hydrogen water generator. The dissolved hydrogen water generator according to claim 1 , wherein the control unit controls the hydrogen water generation unit based on the average value of the difference . The dissolved hydrogen water generator according to claim 1 or 2, further comprising a notification unit for notifying the difference . The hydrogen water generation unit includes an anode feeder and a cathode feeder for electrolyzing water.
When the difference is smaller than a predetermined threshold value, the control unit increases the current for electrolysis supplied to the anode feeding body and the cathode feeding body according to claims 1 to 3. Dissolved hydrogen water generator according to any one of.

Images