JP6995746B2 - 安全な放射性同位体調製および注入のためのシステム - Google Patents
安全な放射性同位体調製および注入のためのシステム Download PDFInfo
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- JP6995746B2 JP6995746B2 JP2018517488A JP2018517488A JP6995746B2 JP 6995746 B2 JP6995746 B2 JP 6995746B2 JP 2018517488 A JP2018517488 A JP 2018517488A JP 2018517488 A JP2018517488 A JP 2018517488A JP 6995746 B2 JP6995746 B2 JP 6995746B2
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Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP15172904.3A EP3106200A1 (en) | 2015-06-19 | 2015-06-19 | A system for safe radioisotope preparation and injection |
| EP15172904.3 | 2015-06-19 | ||
| PCT/EP2016/064221 WO2016203055A2 (en) | 2015-06-19 | 2016-06-20 | A system for safe radioisotope preparation and injection |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020158658A Division JP7066799B2 (ja) | 2015-06-19 | 2020-09-23 | 安全な放射性同位体調製および注入のためのシステム |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2018529969A JP2018529969A (ja) | 2018-10-11 |
| JP6995746B2 true JP6995746B2 (ja) | 2022-02-04 |
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Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018517488A Active JP6995746B2 (ja) | 2015-06-19 | 2016-06-20 | 安全な放射性同位体調製および注入のためのシステム |
| JP2020158658A Active JP7066799B2 (ja) | 2015-06-19 | 2020-09-23 | 安全な放射性同位体調製および注入のためのシステム |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020158658A Active JP7066799B2 (ja) | 2015-06-19 | 2020-09-23 | 安全な放射性同位体調製および注入のためのシステム |
Country Status (13)
| Country | Link |
|---|---|
| US (3) | US12390577B2 (enExample) |
| EP (3) | EP3106200A1 (enExample) |
| JP (2) | JP6995746B2 (enExample) |
| KR (3) | KR102623512B1 (enExample) |
| CN (3) | CN119868729B (enExample) |
| CA (2) | CA2989950A1 (enExample) |
| DK (2) | DK3449972T3 (enExample) |
| ES (1) | ES2951981T3 (enExample) |
| FI (2) | FI3449972T3 (enExample) |
| PL (1) | PL3310428T3 (enExample) |
| PT (1) | PT3310428T (enExample) |
| SI (1) | SI3310428T1 (enExample) |
| WO (1) | WO2016203055A2 (enExample) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2017358321B2 (en) | 2016-11-11 | 2022-01-06 | MedTrace Pharma A/S | Method and system for modelling a human heart and atria |
| SI3338808T1 (sl) | 2016-12-21 | 2023-10-30 | MedTrace Pharma A/S | Diagnostična uporaba radiofarmacevtikov s kratko življenjsko dobo |
| DE102017125606A1 (de) * | 2017-11-02 | 2019-05-02 | Kernkraftwerk Gösgen-Däniken Ag | Ventilblock für ein molchbares und/oder festkörperführendes Leitungssystem und Verteilerleitungssystem |
| TWI684184B (zh) * | 2019-01-23 | 2020-02-01 | 日商住友重機械工業股份有限公司 | 自屏蔽迴旋加速器系統 |
| IT201900012735A1 (it) | 2019-07-24 | 2021-01-24 | Gvs Spa | Connettore a tre vie perfezionato |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2008506428A (ja) | 2004-07-16 | 2008-03-06 | チューリッヒ大学 | 放射活性を正確に分配する方法及び装置 |
| EP2457602A1 (en) | 2010-11-25 | 2012-05-30 | F. Hoffmann-La Roche AG | Infusion pump having dosing unit with safety valve |
| US8602058B1 (en) | 2009-08-12 | 2013-12-10 | Gil Del Castillo | Pushbutton stopcock assembly |
Family Cites Families (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3834372A (en) * | 1973-01-12 | 1974-09-10 | S Turney | Disposable manifold with atmospheric vent |
| US3957082A (en) * | 1974-09-26 | 1976-05-18 | Arbrook, Inc. | Six-way stopcock |
| GB1549100A (en) * | 1977-04-19 | 1979-07-25 | Northern Eng Ind | Rotary control valve |
| US4950230A (en) | 1987-03-19 | 1990-08-21 | Delmed, Inc. | Method and apparatus for bagless continuous ambulatory peritoneal dialysis |
| CA2055297C (en) * | 1990-11-13 | 1996-10-08 | Iwao Kanno | Apparatus and method for producing and automatically injecting h--o |
| JP2501264B2 (ja) | 1991-10-30 | 1996-05-29 | 上村 和夫 | H2 15oの製造装置とh2 15oの注射液製造装置及びh2 15oの自動注射装置 |
| US5482865A (en) * | 1994-06-10 | 1996-01-09 | Associated Universities, Inc. | Apparatus and method for preparing oxygen-15 labeled water H2 [15 O] in an injectable form for use in positron emission tomography |
| EP1920718A1 (en) | 1995-04-20 | 2008-05-14 | ACIST Medical Systems, Inc. | Radiographic contrast material injector |
| JPH09173447A (ja) * | 1995-12-27 | 1997-07-08 | Terumo Corp | 薬液投与用器具および腹膜透析液投与用器具 |
| US6471674B1 (en) | 2000-04-21 | 2002-10-29 | Medrad, Inc. | Fluid delivery systems, injector systems and methods of fluid delivery |
| US7734331B2 (en) * | 2004-03-02 | 2010-06-08 | General Electric Company | Systems, methods and apparatus for preparation, delivery and monitoring of radioisotopes in positron emission tomography |
| ES2303266T3 (es) * | 2004-05-27 | 2008-08-01 | E-Z-Em, Inc. | Sistema, metodo y producto de programa informatico para manipular, mezclar, dispensar e inyectar agentes radiofarmaceuticos. |
| US20070181615A1 (en) * | 2006-02-08 | 2007-08-09 | International Dispensing Corporation | Drip resistant dispensing valve for fluids |
| US7813841B2 (en) * | 2006-03-10 | 2010-10-12 | Ottawa Heart Institute Research Corporation | Rubidium elution system control |
| JP5330234B2 (ja) * | 2006-06-14 | 2013-10-30 | アシスト・メディカル・システムズ,インコーポレイテッド | 医療用注入システムにおける流体不純物除去 |
| FR2906475B1 (fr) * | 2006-09-29 | 2009-01-09 | Lemer Prot Anti X Par Abrevati | Unite medicale pour le prelevement,le calibrage,la dilution et/ou l'injection d'un produit radioactif injectable |
| WO2008083313A2 (en) * | 2007-01-01 | 2008-07-10 | Medrad, Inc. | Methods and systems for integrated radiopharmaceutical generation, preparation, transportation, and administration |
| DE102007003690B4 (de) * | 2007-01-25 | 2009-05-14 | Iprm Intellectual Property Rights Management Ag | Multifunktionsventil |
| CN101801440A (zh) * | 2007-09-13 | 2010-08-11 | 分子制药洞察公司 | 用于和放射性试剂一起使用的输注和输送系统 |
| JP5695908B2 (ja) * | 2007-12-10 | 2015-04-08 | バイエル メディカル ケア インコーポレーテッド | 連続流体輸送システム及び流体輸送方法 |
| EP2259836A2 (en) * | 2008-04-04 | 2010-12-15 | Molecular Insight Pharmaceuticals, Inc. | Radiolabeled treatment infusion system, apparatus, and methods of using the same |
| CN104587552B (zh) * | 2008-06-06 | 2017-11-14 | 拜耳医药保健有限公司 | 用于向患者递送流体注射药丸以及处理有害流体的装置和方法 |
| AR076623A1 (es) | 2009-06-02 | 2011-06-22 | Sanofi Aventis Deutschland | Suministro de dos o mas medicamentos por medio de una unica seleccion de dosis e interfaz de dispensacion |
| CN102686254B (zh) * | 2009-11-09 | 2014-08-06 | 株式会社根本杏林堂 | 带开放功能的单向阀、具备该单向阀的软管单元及药液注入系统 |
| US9959389B2 (en) | 2010-06-24 | 2018-05-01 | Bayer Healthcare Llc | Modeling of pharmaceutical propagation and parameter generation for injection protocols |
| US8937287B2 (en) * | 2012-04-19 | 2015-01-20 | Abt Molecular Imaging, Inc. | Self-referencing radiation detector for use with a radiopharmaceutical quality control testing system |
| US9433728B2 (en) * | 2013-03-01 | 2016-09-06 | Bayer Healthcare Llc | Valveless pharmaceutical infusion system |
| BR112016010770B1 (pt) | 2013-11-14 | 2021-11-23 | David R. Duncan | Torneira com visor de estados funcionais positivo e negativo e válvula de múltiplas portas com indicadores de situações positiva e negativa |
| KR101444705B1 (ko) * | 2014-01-29 | 2014-09-26 | (주)유니테코 | 방사성 의약품 분배장치 |
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Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2008506428A (ja) | 2004-07-16 | 2008-03-06 | チューリッヒ大学 | 放射活性を正確に分配する方法及び装置 |
| US8602058B1 (en) | 2009-08-12 | 2013-12-10 | Gil Del Castillo | Pushbutton stopcock assembly |
| EP2457602A1 (en) | 2010-11-25 | 2012-05-30 | F. Hoffmann-La Roche AG | Infusion pump having dosing unit with safety valve |
| US20130261599A1 (en) | 2010-11-25 | 2013-10-03 | Roche Diagnostics International Ag | Dosing Unit With Safety Valve |
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