JP6983148B2 - 呼吸機能を可能にするために脊髄ネットワークにアクセスすること - Google Patents

呼吸機能を可能にするために脊髄ネットワークにアクセスすること Download PDF

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Publication number
JP6983148B2
JP6983148B2 JP2018501208A JP2018501208A JP6983148B2 JP 6983148 B2 JP6983148 B2 JP 6983148B2 JP 2018501208 A JP2018501208 A JP 2018501208A JP 2018501208 A JP2018501208 A JP 2018501208A JP 6983148 B2 JP6983148 B2 JP 6983148B2
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Prior art keywords
stimulation
respiratory
stimulator
sensor
breathing
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JP2018501208A
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Japanese (ja)
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JP2018524113A (ja
JP2018524113A5 (cg-RX-API-DMAC7.html
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ダニエル・シー・ルー
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University of California
University of California San Diego UCSD
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University of California
University of California San Diego UCSD
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Priority to JP2021188658A priority Critical patent/JP7520800B2/ja
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
    • A61N1/3606—Implantable neurostimulators for stimulating central or peripheral nerve system adapted for a particular treatment
    • A61N1/3611—Respiration control
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/05—Electrodes for implantation or insertion into the body, e.g. heart electrode
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/05—Electrodes for implantation or insertion into the body, e.g. heart electrode
    • A61N1/0551—Spinal or peripheral nerve electrodes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
    • A61N1/36128—Control systems
    • A61N1/36146—Control systems specified by the stimulation parameters
    • A61N1/36167—Timing, e.g. stimulation onset
    • A61N1/36175—Pulse width or duty cycle
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N2/00—Magnetotherapy
    • A61N2/004—Magnetotherapy specially adapted for a specific therapy
    • A61N2/006—Magnetotherapy specially adapted for a specific therapy for magnetic stimulation of nerve tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N2/00—Magnetotherapy
    • A61N2/02—Magnetotherapy using magnetic fields produced by coils, including single turn loops or electromagnets
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
    • A61N1/36128—Control systems
    • A61N1/36146—Control systems specified by the stimulation parameters
    • A61N1/3615—Intensity
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
    • A61N1/36128—Control systems
    • A61N1/36146—Control systems specified by the stimulation parameters
    • A61N1/36167—Timing, e.g. stimulation onset
    • A61N1/36171—Frequency

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Pulmonology (AREA)
  • Electrotherapy Devices (AREA)
  • Magnetic Treatment Devices (AREA)
JP2018501208A 2015-07-13 2016-07-11 呼吸機能を可能にするために脊髄ネットワークにアクセスすること Active JP6983148B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2021188658A JP7520800B2 (ja) 2015-07-13 2021-11-19 呼吸機能を可能にするために脊髄ネットワークにアクセスすること

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562191892P 2015-07-13 2015-07-13
US62/191,892 2015-07-13
PCT/US2016/041802 WO2017011410A1 (en) 2015-07-13 2016-07-11 Accessing spinal network to enable respiratory function

Related Child Applications (1)

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JP2021188658A Division JP7520800B2 (ja) 2015-07-13 2021-11-19 呼吸機能を可能にするために脊髄ネットワークにアクセスすること

Publications (3)

Publication Number Publication Date
JP2018524113A JP2018524113A (ja) 2018-08-30
JP2018524113A5 JP2018524113A5 (cg-RX-API-DMAC7.html) 2019-09-05
JP6983148B2 true JP6983148B2 (ja) 2021-12-17

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JP2018501208A Active JP6983148B2 (ja) 2015-07-13 2016-07-11 呼吸機能を可能にするために脊髄ネットワークにアクセスすること
JP2021188658A Active JP7520800B2 (ja) 2015-07-13 2021-11-19 呼吸機能を可能にするために脊髄ネットワークにアクセスすること

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Country Link
US (2) US20180185642A1 (cg-RX-API-DMAC7.html)
EP (1) EP3322477B1 (cg-RX-API-DMAC7.html)
JP (2) JP6983148B2 (cg-RX-API-DMAC7.html)
CA (1) CA3030615A1 (cg-RX-API-DMAC7.html)
HK (1) HK1255688A1 (cg-RX-API-DMAC7.html)
WO (1) WO2017011410A1 (cg-RX-API-DMAC7.html)

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EP4588503A3 (en) 2011-01-03 2025-10-01 The Regents of the University of California High density epidural stimulation for facilitation of locomotion, posture, voluntary movement, and recovery of autonomic, sexual, vasomotor, and cognitive function after neurological injury
EP2776119B1 (en) 2011-11-11 2019-02-06 The Regents of The University of California Transcutaneous spinal cord stimulation: noninvasive tool for activation of locomotor circuitry
US9393409B2 (en) 2011-11-11 2016-07-19 Neuroenabling Technologies, Inc. Non invasive neuromodulation device for enabling recovery of motor, sensory, autonomic, sexual, vasomotor and cognitive function
US9993642B2 (en) 2013-03-15 2018-06-12 The Regents Of The University Of California Multi-site transcutaneous electrical stimulation of the spinal cord for facilitation of locomotion
EP3049148B1 (en) 2013-09-27 2020-05-20 The Regents Of The University Of California Engaging the cervical spinal cord circuitry to re-enable volitional control of hand function in tetraplegic subjects
WO2016029159A2 (en) 2014-08-21 2016-02-25 The Regents Of The University Of California Regulation of autonomic control of bladder voiding after a complete spinal cord injury
AU2015308779B2 (en) 2014-08-27 2020-06-25 The Regents Of The University Of California Multi-electrode array for spinal cord epidural stimulation
WO2017035512A1 (en) 2015-08-26 2017-03-02 The Regents Of The University Of California Concerted use of noninvasive neuromodulation device with exoskeleton to enable voluntary movement and greater muscle activation when stepping in a chronically paralyzed subject
US11097122B2 (en) 2015-11-04 2021-08-24 The Regents Of The University Of California Magnetic stimulation of the spinal cord to restore control of bladder and/or bowel
CA3051401A1 (en) * 2017-01-24 2018-08-02 The Regents Of The University Of California Accessing spinal network to enable respiratory function
EP4473909A3 (en) 2017-02-17 2025-01-29 The University of British Columbia Apparatus and methods for maintaining physiological functions
WO2018217791A1 (en) 2017-05-23 2018-11-29 The Regents Of The University Of California Accessing spinal networks to address sexual dysfunction
EP3974021B1 (en) 2017-06-30 2023-06-14 ONWARD Medical N.V. A system for neuromodulation
WO2019050896A2 (en) * 2017-09-05 2019-03-14 University Of Florida Research Foundation, Inc. STIMULATION OF NEURONES MOTORS OF SPINAL CORD BY ELECTRICAL SIGNALS
US12357828B2 (en) 2017-12-05 2025-07-15 Ecole Polytechnique Federale De Lausanne (Epfl) System for planning and/or providing neuromodulation
US11992684B2 (en) 2017-12-05 2024-05-28 Ecole Polytechnique Federale De Lausanne (Epfl) System for planning and/or providing neuromodulation
KR102118530B1 (ko) * 2018-02-23 2020-06-03 김민규 펄스 자기장을 이용한 미주신경 자극 방법 및 장치
EP3840638A4 (en) * 2018-08-23 2022-05-18 The Regents Of The University Of California NON-INVASIVE SPINAL CORD STIMULATION FOR NERVE ROOT PALSY, CAUDA SYNDROME AND RESTORATION OF FUNCTION OF THE UPPER EXTREMITIES
ES2911465T3 (es) 2018-11-13 2022-05-19 Onward Medical N V Sistema de control para la reconstrucción y/o restauración del movimiento de un paciente
EP3695878B1 (en) 2019-02-12 2023-04-19 ONWARD Medical N.V. A system for neuromodulation
EP3827875B1 (en) 2019-11-27 2023-07-05 ONWARD Medical N.V. Neuromodulation system
DE19211698T1 (de) 2019-11-27 2021-09-02 Onward Medical B.V. Neuromodulation system
EP3875142A1 (en) * 2020-03-04 2021-09-08 ONWARD Medical B.V. A neuromodulation system
US12168096B2 (en) * 2021-01-27 2024-12-17 Chimei Medical Center Ventilator-weaning timing prediction system, program product thereof and method for building and using the same
US20240198100A1 (en) * 2021-04-14 2024-06-20 The Regents Of The University Of California Spinal cord stimulation for conditioning respiratory muscles

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US6234985B1 (en) * 1998-06-11 2001-05-22 Cprx Llc Device and method for performing cardiopulmonary resuscitation
US6463327B1 (en) * 1998-06-11 2002-10-08 Cprx Llc Stimulatory device and methods to electrically stimulate the phrenic nerve
US20110288609A1 (en) * 2003-10-15 2011-11-24 Rmx, Llc Therapeutic diaphragm stimulation device and method
US7422555B2 (en) * 2003-12-30 2008-09-09 Jacob Zabara Systems and methods for therapeutically treating neuro-psychiatric disorders and other illnesses
EP1750799A2 (en) * 2004-05-04 2007-02-14 The Cleveland Clinic Foundation Methods of treating medical conditions by neuromodulation of the sympathetic nervous system
US7657316B2 (en) * 2005-02-25 2010-02-02 Boston Scientific Neuromodulation Corporation Methods and systems for stimulating a motor cortex of the brain to treat a medical condition
US20070060954A1 (en) * 2005-02-25 2007-03-15 Tracy Cameron Method of using spinal cord stimulation to treat neurological disorders or conditions
US7920915B2 (en) * 2005-11-16 2011-04-05 Boston Scientific Neuromodulation Corporation Implantable stimulator
US7805195B2 (en) * 2005-03-24 2010-09-28 Vanderbilt University Respiratory triggered, bilateral laryngeal stimulator to restore normal ventilation in vocal fold paralysis
US8036750B2 (en) * 2005-06-13 2011-10-11 Cardiac Pacemakers, Inc. System for neural control of respiration
US8352036B2 (en) * 2009-01-19 2013-01-08 Anthony DiMarco Respiratory muscle activation by spinal cord stimulation
WO2010104700A1 (en) * 2009-03-09 2010-09-16 Cardiac Pacemakers, Inc. Systems for autonomic nerve modulation comprising electrodes implantable in a lymphatic vessel
US10279163B2 (en) * 2011-03-10 2019-05-07 Electrocore, Inc. Electrical and magnetic stimulators used to treat migraine/sinus headache, rhinitis, sinusitis, rhinosinusitis, and comorbid disorders
CA2877049C (en) * 2012-06-21 2022-08-16 Simon Fraser University Transvascular diaphragm pacing systems and methods of use
US9993642B2 (en) * 2013-03-15 2018-06-12 The Regents Of The University Of California Multi-site transcutaneous electrical stimulation of the spinal cord for facilitation of locomotion
EP3049148B1 (en) * 2013-09-27 2020-05-20 The Regents Of The University Of California Engaging the cervical spinal cord circuitry to re-enable volitional control of hand function in tetraplegic subjects
EP3185950A4 (en) * 2014-08-27 2018-04-11 The Regents of The University of California Methods of fabricating a multi-electrode array for spinal cord epidural stimulation
AU2015308779B2 (en) * 2014-08-27 2020-06-25 The Regents Of The University Of California Multi-electrode array for spinal cord epidural stimulation

Also Published As

Publication number Publication date
WO2017011410A1 (en) 2017-01-19
US20250295923A1 (en) 2025-09-25
JP2018524113A (ja) 2018-08-30
EP3322477A1 (en) 2018-05-23
HK1255688A1 (zh) 2019-08-23
JP7520800B2 (ja) 2024-07-23
US20180185642A1 (en) 2018-07-05
CA3030615A1 (en) 2017-01-19
JP2022016548A (ja) 2022-01-21
EP3322477A4 (en) 2019-03-20
EP3322477B1 (en) 2025-12-10

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