JP6960982B2 - クランプチャンバおよび吸入装置 - Google Patents
クランプチャンバおよび吸入装置 Download PDFInfo
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- JP6960982B2 JP6960982B2 JP2019231996A JP2019231996A JP6960982B2 JP 6960982 B2 JP6960982 B2 JP 6960982B2 JP 2019231996 A JP2019231996 A JP 2019231996A JP 2019231996 A JP2019231996 A JP 2019231996A JP 6960982 B2 JP6960982 B2 JP 6960982B2
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Description
いくつかの実施形態の一態様は、加熱気化される原薬を、一体化された加熱要素を提供するカートリッジに合わせて加工および包装することに関する。
・ カートリッジの最大寸法に対して再現可能な位置にパレットを位置決めする機能;
・ パレットに機械的安定性(例えば、1つ以上の縁部の支持、屈曲に抵抗する剛性、および/または定着)を提供する機能;
・ カートリッジと相互作用する形状の機械的要素によってカートリッジの輸送を可能にする取付け要素(例えば、掛止要素/定着要素および/または掛止面/定着面)を提供する機能;
・ 加熱要素の2つの平行な面の間に絶縁体を設けて自己接触を防止する機能;および/または
・ 加熱要素とカートリッジとの接着/定着/埋め込みのための表面領域および/またはかさ容積領域を提供する機能の1つ以上を実行する。
・ 用量カートリッジを物質気化装置に受け入れるためにカートリッジ容器に取り付けられ、また、
・ 用量部を投与するためにカートリッジ容器(マガジン)から取り外される、カートリッジ容器に関する。
<一体型加熱要素を有する用量カートリッジ>
ここで、いくつかの実施形態に係る、分解された用量カートリッジ2300の概略図(図5A)および組み立てられた用量カートリッジ2300の概略図(図5B)である図5Aおよび図5Bを参照する。また、いくつかの実施形態に係る、用量カートリッジ2350,2360,2370,2380,2390,2395の代替的構造を概略的に例示する図5C〜図5Mを参照する。図5C,5E,5G,5J,5Lは、分解された用量カートリッジを表す。図5D,5F,5H,5K,5Mは、組み立てられた用量カートリッジを表す。
・ 任意選択的に急速気化するように形成された(例えば扁平化することによって形成された)薬物用量装填物2304;
・ 薬物用量装填物2304のための機械的支持部(例えば、任意選択的にフレーム形状のハウジング2301内に包囲することによる支持);
・ カートリッジ2300の輸送を容易化するための取付け要素(例えば、顎状ラッチ(latch mandibles)2302);および/または
・ 薬物用量装填物2304の気化手段(例えば、電気抵抗加熱要素2306、任意選択的にメッシュ)を備える。
ここで、いくつかの実施形態に係る、吸入装置を用いて用量部パッケージの中で使用される粒状化した植物性物質を調製する方法の概略的なフローチャートである図1を参照する。また、ここで、いくつかの実施形態に係る、植物性物質のすりつぶし装置2200の概略図である図3も参照する。また、ここで、いくつかの実施形態に係る、植物性物質のすりつぶしヘッド2204のすりつぶしプレート2220の概略図である図4も参照する。
<用量カートリッジに合わせた植物性物質の包装>
ここで、いくつかの実施形態に係る、吸入装置を用いて使用される用量カートリッジに合わせて植物性物質を包装する方法の概略的フローチャートである図2を参照する。
<用量カートリッジカルーセルおよび気化装置>
ここで、いくつかの実施形態に係る、吸入装置と共に使用されるカルーセル型の用量部送達システム2340を例示する概略図である図6A〜図6Eを参照する。
ここで、いくつかの実施形態に係る、カルーセルから装填される用量部送達装置であって、用量部自体を送達するためにカルーセルから分離可能な用量部送達装置を例示する概略図である図8Aおよび図8Bを参照する。
ここで、いくつかの実施形態に係る、2つの別個のカルーセルマガジン内に保持された複数の用量カートリッジからの物質を潜在的に同時に投与するために配置されたカルーセルを例示する概略図である図10を参照する。
本出願は、2014年6月30日に出願された米国仮特許出願第62/019,225号;2014年8月11日に出願された米国仮特許出願第62/035,588号;2014年12月1日に出願された米国仮特許出願第62/085,772号;2014年12月2日に出願された米国仮特許出願第62/086,208号;および、2015年5月21日に出願された米国仮特許出願第62/164,710号の優先権を、米国特許法第119条(e)に基づき主張する。本出願は、「単離した物質の気化および吸入のための方法および装置」(“METHOD AND DEVICE FOR VAPORIZATION AND INHALATION OF ISOLATED SUBSTANCES”)と題されかつ2015年6月30日に出願された併行出願(代理人整理番号:62783);「流量制御吸入装置」(“FLOW REGULATING INHALER DEVICE”)と題されかつ2015年6月30日に出願された併行出願(代理人整理番号:62784);および、「活性薬剤の肺送達のための方法、装置、およびシステム」(“METHODS, DEVICES AND SYSTEMS FOR PULMONARY DELIVERY OF ACTIVE AGENTS”)と題されかつ2015年6月30日に出願された併行出願(代理人整理番号:62791、63210、および63211)の優先権を、米国特許法第119条(e)に基づき主張するものであり、これら文書の開示内容は参照によりその全体が本明細書に援用される。
Claims (19)
- 加熱気化される原薬を使用者に肺送達するための吸入器用用量カートリッジのためのクランプチャンバであって、
前記吸入器用用量カートリッジを格納位置から使用位置に移動するカートリッジ輸送部であって、前記カートリッジ輸送部は、前記用量カートリッジの受入れ領域と連結する形状の用量部引出しアームであって、移動することによって、前記用量カートリッジが使用位置にまたは使用位置から移動される、用量部引出しアームを備える、前記カートリッジ輸送部と、
加熱気化される原薬が上記クランプチャンバの空気路と密封状態で位置合わせされるように、選択された用量カートリッジと係合する少なくとも2つのクランプ部材と、
前記クランプチャンバの中の前記吸入器用用量カートリッジの電気抵抗加熱要素の少なくとも2つの電気接触受入れ領域と電気接触するように位置決めされた電極と、
を備える、クランプチャンバ。 - 前記クランプ部材の少なくとも1つは、少なくとも1つのエアシールを備える、請求項1に記載のクランプチャンバ。
- 前記少なくとも1つのエアシールは、前記用量カートリッジの周りを閉鎖して、前記空気路に沿った空気流の移動以外の空気流の移動を防止する、請求項2に記載のクランプチャンバ。
- 前記少なくとも1つのエアシールは、弾性的に変形可能な材料を含む、請求項2および3のいずれか一項に記載のクランプチャンバ。
- 前記クランプ部材は、それぞれが前記電極の少なくとも1つを備える、請求項1から4のいずれか一項に記載のクランプチャンバ。
- 加熱気化される原薬の揮発性成分を前記空気路に閉じ込める、請求項1から5のいずれか一項に記載のクランプチャンバ。
- 前記電極は、それぞれ前記電気抵抗加熱要素の電気接触受入れ領域に接触する平面を画定する、請求項1から6のいずれか一項に記載のクランプチャンバ。
- 前記電極は、それぞれ前記電気抵抗加熱要素の電気接触受入れ領域に接触する湾曲面を画定する、請求項1から6のいずれか一項に記載のクランプチャンバ。
- 前記電極は、前記吸入器用用量カートリッジの対向表面に電気接触するように位置決めされた、請求項1から8のいずれか一項に記載のクランプチャンバ。
- 前記カートリッジ輸送部は、前記用量カートリッジの係止部材と係合する形状を有する、請求項1から9のいずれか一項に記載のクランプチャンバ。
- それぞれが対応する吸入器用用量カートリッジを移動する、複数のカートリッジ輸送部と、
前記複数のカートリッジ輸送部に対応する複数のクランプ部材と、
前記カートリッジ輸送部のそれぞれに対応する電極と、
を備える、請求項1から10のいずれか一項に記載のクランプチャンバ。 - 前記電極と前記電気接触受入れ領域との間の接触力は、約500ニュートンである、請求項1から11のいずれか一項に記載のクランプチャンバ。
- 複数の用量カートリッジが格納されたマガジンとともに使用される吸入装置であって、
請求項1から12のいずれか一項に記載のクランプチャンバと、
投与計画に基づき前記複数の用量カートリッジから用量カートリッジを選択するように構成された制御部と、
を備える、吸入装置。 - カルーセル型のマガジンに取り付けるまたは受け入れる形状を有する、請求項13に記載の吸入装置。
- 線型のマガジンに取り付けるまたは受け入れる形状を有する、請求項13および14のいずれか一項に記載の吸入装置。
- 前記マガジンの移動を作動するモータを備え、前記制御部は、前記モータの動作を制御する、請求項13から15のいずれか一項に記載の吸入装置。
- 前記制御部は、前記電気抵抗加熱要素による前記用量カートリッジの加熱を制御する、請求項13から16のいずれか一項に記載の吸入装置。
- 前記電気抵抗加熱要素は、空気が通過可能である、請求項13から17のいずれか一項に記載の吸入装置。
- 前記用量カートリッジの空気流および/または温度を示すデータを提供する1つまたは複数のセンサを備える、請求項13から18のいずれか一項に記載の吸入装置。
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US201462019225P | 2014-06-30 | 2014-06-30 | |
US62/019,225 | 2014-06-30 | ||
US201462035588P | 2014-08-11 | 2014-08-11 | |
US62/035,588 | 2014-08-11 | ||
US201462085772P | 2014-12-01 | 2014-12-01 | |
US62/085,772 | 2014-12-01 | ||
US201462086208P | 2014-12-02 | 2014-12-02 | |
US62/086,208 | 2014-12-02 | ||
US201562164710P | 2015-05-21 | 2015-05-21 | |
US62/164,710 | 2015-05-21 | ||
PCT/IL2015/050677 WO2016001925A1 (en) | 2014-06-30 | 2015-06-30 | Drug dose cartridge for an inhaler device |
JP2016576071A JP6663867B2 (ja) | 2014-06-30 | 2015-06-30 | 吸入装置用の薬物用量カートリッジ |
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