JP6945452B2 - 細菌感染症の処置方法 - Google Patents

細菌感染症の処置方法 Download PDF

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JP6945452B2
JP6945452B2 JP2017555494A JP2017555494A JP6945452B2 JP 6945452 B2 JP6945452 B2 JP 6945452B2 JP 2017555494 A JP2017555494 A JP 2017555494A JP 2017555494 A JP2017555494 A JP 2017555494A JP 6945452 B2 JP6945452 B2 JP 6945452B2
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compound
meropenem
pharmaceutically acceptable
combination
hours
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JP2018513188A5 (enExample
JP2018513188A (ja
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グリフィス、デイビッド、シー．
ダドリー、マイケル、エヌ．
ルーティット、ジェフリー、エス．
ロモフスカヤ、オルガ
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レンペックス・ファーマシューティカルズ・インコーポレイテッド
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/69—Boron compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/407—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with other heterocyclic ring systems, e.g. ketorolac, physostigmine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

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  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2017555494A 2015-04-24 2016-04-20 細菌感染症の処置方法 Active JP6945452B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2021101472A JP7245289B2 (ja) 2015-04-24 2021-06-18 細菌感染症の処置方法

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562152668P 2015-04-24 2015-04-24
US62/152,668 2015-04-24
PCT/US2016/028437 WO2016172208A1 (en) 2015-04-24 2016-04-20 Methods of treating bacterial infections

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JP2021101472A Division JP7245289B2 (ja) 2015-04-24 2021-06-18 細菌感染症の処置方法

Publications (3)

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JP2018513188A JP2018513188A (ja) 2018-05-24
JP2018513188A5 JP2018513188A5 (enExample) 2019-05-30
JP6945452B2 true JP6945452B2 (ja) 2021-10-06

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JP2017555494A Active JP6945452B2 (ja) 2015-04-24 2016-04-20 細菌感染症の処置方法
JP2021101472A Active JP7245289B2 (ja) 2015-04-24 2021-06-18 細菌感染症の処置方法

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JP2021101472A Active JP7245289B2 (ja) 2015-04-24 2021-06-18 細菌感染症の処置方法

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US (2) US20160339045A1 (enExample)
EP (1) EP3285776B1 (enExample)
JP (2) JP6945452B2 (enExample)
CN (2) CN107530364A (enExample)
AU (1) AU2016252555A1 (enExample)
CA (1) CA2982911C (enExample)
ES (1) ES2942329T3 (enExample)
WO (1) WO2016172208A1 (enExample)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2599791C2 (ru) 2010-08-10 2016-10-20 Ремпекс Фармасьютикэлз, Инч. Циклические бороновые кислотно-эфирные производные и их использование в терапии
AU2014204045B2 (en) 2013-01-04 2018-10-18 Rempex Pharmaceuticals, Inc. Boronic acid derivatives and therapeutic uses thereof
WO2015171398A1 (en) 2014-05-05 2015-11-12 Rempex Pharmaceuticals, Inc. Salts and polymorphs of cyclic boronic acid ester derivatives and therapeutic uses thereof
RS59488B1 (sr) 2014-05-05 2019-12-31 Rempex Pharmaceuticals Inc Sinteza boronatnih soli i njihove upotrebe
JP6672176B2 (ja) 2014-05-19 2020-03-25 レンペックス・ファーマシューティカルズ・インコーポレイテッド ボロン酸誘導体およびその治療的使用
AU2015284307A1 (en) 2014-07-01 2017-02-02 Rempex Pharmaceuticals, Inc. Boronic acid derivatives and therapeutic uses thereof
US10662205B2 (en) 2014-11-18 2020-05-26 Qpex Biopharma, Inc. Cyclic boronic acid ester derivatives and therapeutic uses thereof
US20180051041A1 (en) 2015-03-17 2018-02-22 Rempex Pharmaceuticals, Inc. Boronic acid derivatives and therapeutic uses thereof
JP7060245B2 (ja) 2016-06-30 2022-04-26 キューペックス バイオファーマ， インコーポレイテッド ボロン酸誘導体およびその治療的使用
PT3565551T (pt) * 2017-01-09 2024-06-14 Melinta Therapeutics Inc Métodos de tratamento de infeções bacterianas com uma combinação de vaborbactam e meropenem
AU2018345317B2 (en) * 2017-10-03 2024-10-24 Melinta Therapeutics, Inc. Methods of treating bacterial infections
CA3078627A1 (en) 2017-10-11 2019-04-18 Qpex Biopharma, Inc. Boronic acid derivatives and synthesis thereof
EP3781576B1 (en) 2018-04-20 2024-06-12 Qpex Biopharma, Inc. Boronic acid derivatives and therapeutic uses thereof
CN116098993B (zh) * 2022-11-17 2024-10-25 中国农业科学院特产研究所 一种狐、貉肺炎三联灭活疫苗及其制备方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4783443A (en) 1986-03-03 1988-11-08 The University Of Chicago Amino acyl cephalosporin derivatives
RU2599791C2 (ru) 2010-08-10 2016-10-20 Ремпекс Фармасьютикэлз, Инч. Циклические бороновые кислотно-эфирные производные и их использование в терапии
US10561675B2 (en) * 2012-06-06 2020-02-18 Rempex Pharmaceuticals, Inc. Cyclic boronic acid ester derivatives and therapeutic uses thereof

Also Published As

Publication number Publication date
AU2016252555A1 (en) 2017-11-09
JP7245289B2 (ja) 2023-03-23
HK1249432A1 (en) 2018-11-02
JP2018513188A (ja) 2018-05-24
US20160339045A1 (en) 2016-11-24
CN107530364A (zh) 2018-01-02
JP2021143196A (ja) 2021-09-24
WO2016172208A1 (en) 2016-10-27
US20190105337A1 (en) 2019-04-11
EP3285776A4 (en) 2019-01-23
CA2982911A1 (en) 2016-10-27
CN112755039A (zh) 2021-05-07
CA2982911C (en) 2023-10-03
EP3285776A1 (en) 2018-02-28
ES2942329T3 (es) 2023-05-31
EP3285776B1 (en) 2022-12-21

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