JP6938835B2 - レプチン欠乏状態を治療するためのｃｄ２４タンパク質の使用 - Google Patents

レプチン欠乏状態を治療するためのｃｄ２４タンパク質の使用 Download PDF

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JP6938835B2
JP6938835B2 JP2018539976A JP2018539976A JP6938835B2 JP 6938835 B2 JP6938835 B2 JP 6938835B2 JP 2018539976 A JP2018539976 A JP 2018539976A JP 2018539976 A JP2018539976 A JP 2018539976A JP 6938835 B2 JP6938835 B2 JP 6938835B2
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JP2019506408A5 (https=
JP2019506408A (ja
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リウ，　ヤン
ヤン リウ，
パン ジェン，
パン ジェン，
マーティン デベンポート，
マーティン デベンポート，
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オンコイミューン， インコーポレイテッド
オンコイミューン， インコーポレイテッド
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/177—Receptors; Cell surface antigens; Cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/177—Receptors; Cell surface antigens; Cell surface determinants
    • A61K38/1774—Immunoglobulin superfamily (e.g. CD2, CD4, CD8, ICAM molecules, B7 molecules, Fc-receptors, MHC-molecules)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/2264—Obesity-gene products, e.g. leptin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
    • A61K47/6801—Drug-antibody or immunoglobulin conjugates defined by the pharmacologically or therapeutically active agent
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70596—Molecules with a "CD"-designation not provided for elsewhere
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

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  • Health & Medical Sciences (AREA)
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  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Organic Chemistry (AREA)
  • Cell Biology (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Genetics & Genomics (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Toxicology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
JP2018539976A 2016-02-02 2017-02-02 レプチン欠乏状態を治療するためのｃｄ２４タンパク質の使用 Expired - Fee Related JP6938835B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201662290202P 2016-02-02 2016-02-02
US62/290,202 2016-02-02
PCT/US2017/016120 WO2017136492A1 (en) 2016-02-02 2017-02-02 Use of cd24 proteins for treating leptin-deficient conditions

Publications (3)

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JP2019506408A JP2019506408A (ja) 2019-03-07
JP2019506408A5 JP2019506408A5 (https=) 2020-03-12
JP6938835B2 true JP6938835B2 (ja) 2021-09-22

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JP2018539976A Expired - Fee Related JP6938835B2 (ja) 2016-02-02 2017-02-02 レプチン欠乏状態を治療するためのｃｄ２４タンパク質の使用

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US (2) US10799558B2 (https=)
EP (1) EP3411062B1 (https=)
JP (1) JP6938835B2 (https=)
KR (1) KR20180120145A (https=)
CN (1) CN109069583B (https=)
CA (1) CA3012466A1 (https=)
SG (1) SG11201806338SA (https=)
WO (1) WO2017136492A1 (https=)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11547741B2 (en) * 2017-05-22 2023-01-10 Oncoimmune, Inc. Methods of use of soluble CD24 for treating immune related adverse events in cancer therapies
JP2021523929A (ja) * 2018-03-05 2021-09-09 オンコイミューン， インコーポレイテッド 後天性免疫不全症候群（ｈｉｖ／ａｉｄｓ）の治療のための可溶性ｃｄ２４の使用方法
WO2019236474A1 (en) * 2018-06-04 2019-12-12 Oncoimmune, Inc. Methods of use of cd24 for the prevention and treatment of leukemia relapse
EP3921338A4 (en) * 2019-02-06 2022-11-23 Oncoimmune Inc. TARGETED CD24-SIGLEC INTERACTIONS TO TREAT AND PREVENT NON-ALCOHOLIC STEATOHEPATITIS
US20220000974A1 (en) * 2019-02-06 2022-01-06 Oncolmmune, Inc. Targeting CD24-Siglec Interactions for Treating Subjects with Prediabetes or Diabetes

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1267909B1 (en) * 2000-03-29 2010-07-28 The Ohio State University Research Foundation Methods of blocking tissue destruction by autoreactive t cells
WO2004106495A2 (en) * 2003-05-29 2004-12-09 Millennium Pharmaceuticals, Inc. Compositions, kits, and methods for identification, assessment, prevention, and therapy of breast cancer
DK2563385T3 (da) * 2010-04-28 2017-11-06 Oncoimmune Inc Fremgangsmåder til anvendelse af opløselig cd24 til behandling af reumatoid artritis
SG11201401811WA (en) * 2011-08-30 2014-09-26 Amc Amsterdam Method for preventing and/or treating insulin resistance
HK1214628A1 (zh) 2012-11-05 2016-07-29 Pronai Therapeutics, Inc. 寡核苷酸癌症療法的給藥和施用

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Publication number Publication date
US10799558B2 (en) 2020-10-13
EP3411062B1 (en) 2020-11-25
US20190038716A1 (en) 2019-02-07
US20210162006A1 (en) 2021-06-03
CN109069583A (zh) 2018-12-21
WO2017136492A1 (en) 2017-08-10
CN109069583B (zh) 2021-09-21
JP2019506408A (ja) 2019-03-07
EP3411062A4 (en) 2019-09-25
CA3012466A1 (en) 2017-08-10
SG11201806338SA (en) 2018-08-30
KR20180120145A (ko) 2018-11-05
EP3411062A1 (en) 2018-12-12

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