JP6938484B2 - 使い捨てオートインジェクタ - Google Patents

使い捨てオートインジェクタ Download PDF

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Publication number
JP6938484B2
JP6938484B2 JP2018518694A JP2018518694A JP6938484B2 JP 6938484 B2 JP6938484 B2 JP 6938484B2 JP 2018518694 A JP2018518694 A JP 2018518694A JP 2018518694 A JP2018518694 A JP 2018518694A JP 6938484 B2 JP6938484 B2 JP 6938484B2
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JP
Japan
Prior art keywords
needle
injector
auto
mechanical
shaft
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
JP2018518694A
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English (en)
Japanese (ja)
Other versions
JP2018531702A5 (enExample
JP2018531702A (ja
Inventor
クヌーセン，ハンス・ステンベア
プラムベック，クリスティアン
エーレンシュレーガー，ラスムス
ヨアンセン，ヨーウエン
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Amgen Inc
Original Assignee
Amgen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Amgen Inc filed Critical Amgen Inc
Publication of JP2018531702A publication Critical patent/JP2018531702A/ja
Publication of JP2018531702A5 publication Critical patent/JP2018531702A5/ja
Priority to JP2021140783A priority Critical patent/JP7413325B2/ja
Application granted granted Critical
Publication of JP6938484B2 publication Critical patent/JP6938484B2/ja
Active legal-status Critical Current
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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
    • A61M5/2033—Spring-loaded one-shot injectors with or without automatic needle insertion
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142—Pressure infusion, e.g. using pumps
    • A61M5/145—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons
    • A61M5/1452—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons pressurised by means of pistons
    • A61M5/1454—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons pressurised by means of pistons spring-actuated, e.g. by a clockwork
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
    • A61M5/3202—Devices for protection of the needle before use, e.g. caps
    • A61M5/3204—Needle cap remover, i.e. devices to dislodge protection cover from needle or needle hub, e.g. deshielding devices
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
    • A61M5/3205—Apparatus for removing or disposing of used needles or syringes, e.g. containers; Means for protection against accidental injuries from used needles
    • A61M5/321—Means for protection against accidental injuries by used needles
    • A61M5/3243—Means for protection against accidental injuries by used needles being axially-extensible, e.g. protective sleeves coaxially slidable on the syringe barrel
    • A61M5/326—Fully automatic sleeve extension, i.e. in which triggering of the sleeve does not require a deliberate action by the user
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142—Pressure infusion, e.g. using pumps
    • A61M5/14244—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body
    • A61M5/14248—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body of the skin patch type
    • A61M2005/14252—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body of the skin patch type with needle insertion means
    • A61M2005/14256—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body of the skin patch type with needle insertion means with means for preventing access to the needle after use
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142—Pressure infusion, e.g. using pumps
    • A61M5/145—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons
    • A61M2005/14506—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons mechanically driven, e.g. spring or clockwork
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
    • A61M2005/206—With automatic needle insertion
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31511—Piston or piston-rod constructions, e.g. connection of piston with piston-rod
    • A61M2005/31518—Piston or piston-rod constructions, e.g. connection of piston with piston-rod designed to reduce the overall size of an injection device, e.g. using flexible or pivotally connected chain-like rod members
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
    • A61M5/3205—Apparatus for removing or disposing of used needles or syringes, e.g. containers; Means for protection against accidental injuries from used needles
    • A61M5/321—Means for protection against accidental injuries by used needles
    • A61M5/3243—Means for protection against accidental injuries by used needles being axially-extensible, e.g. protective sleeves coaxially slidable on the syringe barrel
    • A61M5/326—Fully automatic sleeve extension, i.e. in which triggering of the sleeve does not require a deliberate action by the user
    • A61M2005/3267—Biased sleeves where the needle is uncovered by insertion of the needle into a patient's body

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Environmental & Geological Engineering (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
JP2018518694A 2015-10-28 2016-10-28 使い捨てオートインジェクタ Active JP6938484B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2021140783A JP7413325B2 (ja) 2015-10-28 2021-08-31 使い捨てオートインジェクタ

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP15191929.7A EP3162395A1 (en) 2015-10-28 2015-10-28 Single-use auto-injector
EP15191929.7 2015-10-28
PCT/EP2016/076156 WO2017072333A1 (en) 2015-10-28 2016-10-28 Single-use auto-injector

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2021140783A Division JP7413325B2 (ja) 2015-10-28 2021-08-31 使い捨てオートインジェクタ

Publications (3)

Publication Number Publication Date
JP2018531702A JP2018531702A (ja) 2018-11-01
JP2018531702A5 JP2018531702A5 (enExample) 2021-04-30
JP6938484B2 true JP6938484B2 (ja) 2021-09-22

Family

ID=54360949

Family Applications (4)

Application Number Title Priority Date Filing Date
JP2018518694A Active JP6938484B2 (ja) 2015-10-28 2016-10-28 使い捨てオートインジェクタ
JP2021140783A Active JP7413325B2 (ja) 2015-10-28 2021-08-31 使い捨てオートインジェクタ
JP2023043876A Pending JP2023075320A (ja) 2015-10-28 2023-03-20 使い捨てオートインジェクタ
JP2025066707A Pending JP2025103048A (ja) 2015-10-28 2025-04-15 使い捨てオートインジェクタ

Family Applications After (3)

Application Number Title Priority Date Filing Date
JP2021140783A Active JP7413325B2 (ja) 2015-10-28 2021-08-31 使い捨てオートインジェクタ
JP2023043876A Pending JP2023075320A (ja) 2015-10-28 2023-03-20 使い捨てオートインジェクタ
JP2025066707A Pending JP2025103048A (ja) 2015-10-28 2025-04-15 使い捨てオートインジェクタ

Country Status (15)

Country Link
US (3) US11033684B2 (enExample)
EP (4) EP3162395A1 (enExample)
JP (4) JP6938484B2 (enExample)
AU (4) AU2016347644B2 (enExample)
CA (1) CA3002301A1 (enExample)
CY (1) CY1122354T1 (enExample)
DK (1) DK3368101T3 (enExample)
ES (2) ES2959440T3 (enExample)
HU (1) HUE045575T2 (enExample)
LT (1) LT3368101T (enExample)
MX (2) MX395072B (enExample)
PL (1) PL3368101T3 (enExample)
PT (1) PT3368101T (enExample)
SI (1) SI3368101T1 (enExample)
WO (1) WO2017072333A1 (enExample)

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GB2549750A (en) * 2016-04-27 2017-11-01 Owen Mumford Ltd Medicament delivery device
US10376656B2 (en) * 2016-05-18 2019-08-13 Portal Instruments, Inc. Side-angle decapping of pre-filled syringe
US20210353877A1 (en) * 2017-05-18 2021-11-18 Sanofi-Aventis Deutschland Gmbh Drug delivery device
CA3073835A1 (en) 2017-08-30 2019-03-07 Pirouette Medical LLC Compact auto-injector
US10441714B2 (en) 2017-10-05 2019-10-15 Pirouette Medical LLC Protective case for an auto-injector
US11033678B2 (en) 2017-11-20 2021-06-15 Agist Medical Systems, Inc. Compact injector drive
US11040147B2 (en) 2017-11-21 2021-06-22 Acist Medical Systems, Inc. Injector position sensing
AU2019235530B2 (en) 2018-03-13 2025-01-02 Mcdermott Laboratories Limited Devices for injecting medicaments and methods of use
WO2019192662A1 (en) 2018-04-04 2019-10-10 Cpu Innovation Aps Auto injector with improved functionality
EP3801691B1 (en) 2018-05-24 2024-12-11 Novartis AG Automatic drug delivery device
US12453822B2 (en) 2019-02-26 2025-10-28 Becton Dickinson France Auto-injector with audio indicator
KR102421966B1 (ko) * 2019-12-27 2022-07-19 지피헬스 주식회사 길이 단축형 휴대용 자동주사 장치
WO2022147985A1 (en) * 2021-01-05 2022-07-14 Medtrum Technologies Inc. A skin patch drug infusion device
US11872369B1 (en) 2021-02-18 2024-01-16 Fresenius Kabi Deutschland Gmbh Wearable medicament delivery device with leakage and skin contact sensing and method of use thereof
US11311666B1 (en) 2021-02-18 2022-04-26 Fresenius Kabi Deutschland Gmbh Modular wearable medicament delivery device and method of use thereof
US11464902B1 (en) 2021-02-18 2022-10-11 Fresenius Kabi Deutschland Gmbh Wearable medicament delivery device with compressible reservoir and method of use thereof
US11497847B1 (en) 2021-02-19 2022-11-15 Fresenius Kabi Deutschland Gmbh Wearable injector with adhesive substrate
US11426523B1 (en) 2021-02-19 2022-08-30 Fresenius Kabi Deutschland Gmbh Drug delivery assembly including a removable cartridge
US11607505B1 (en) 2021-02-19 2023-03-21 Fresenius Kabi Deutschland Gmbh Wearable injector with sterility sensors
US11406755B1 (en) 2021-02-19 2022-08-09 Fresenius Kabi Deutschland Gmbh Sensing fluid flow irregularities in an on-body injector
US11413394B1 (en) 2021-02-19 2022-08-16 Fresenius Kabi Deutschland Gmbh Display for wearable drug delivery device
US11633537B1 (en) 2021-02-19 2023-04-25 Fresenius Kabi Deutschland Gmbh Drug delivery assembly including a pre-filled cartridge
US11344682B1 (en) 2021-02-19 2022-05-31 Fresenius Kabi Deutschland Gmbh Drug supply cartridge with visual use indicator and delivery devices that use the same
US11419976B1 (en) 2021-04-30 2022-08-23 Fresenius Kabi Deutschland Gmbh Wearable drug delivery device with pressurized fluid dispensing
US11529459B1 (en) 2021-04-30 2022-12-20 Fresenius Kabi Deutschland Gmbh Wearable injector with adhesive module
US11351300B1 (en) 2021-04-30 2022-06-07 Fresenius Kabl Deutschland GmbH Drug dispensing system with replaceable drug supply cartridges
US11504470B1 (en) 2021-04-30 2022-11-22 Fresenius Kabi Deutschland Gmbh Deformable drug reservoir for wearable drug delivery device
US11717608B1 (en) 2021-05-03 2023-08-08 Fresenius Kabi Deutschland Gmbh Drug delivery assembly including an adhesive pad
US11484646B1 (en) 2021-05-04 2022-11-01 Fresenius Kabi Deutschland Gmbh Sealing systems for a reservoir of an on-body injector
WO2024251793A1 (en) * 2023-06-05 2024-12-12 Sanofi Drug delivery device
WO2024256913A1 (en) * 2023-06-16 2024-12-19 Janssen Biotech, Inc. Drug delivery device

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US6585699B2 (en) * 2000-04-13 2003-07-01 Nna/S Drug delivery device provided with a one-way mechanism
US6692472B2 (en) * 2000-05-04 2004-02-17 Novo Nordisk A/S Injection device, a preassembled dose setting and injection mechanism for an injection device, and a method of assembling an injection device
AU2002357520A1 (en) * 2001-12-27 2003-07-15 Menicon Co., Ltd. Cartridge syringe, cartridge and ophthalmologic syringe set equipped with the cartridge syringe
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WO2011101376A1 (en) * 2010-02-18 2011-08-25 Sanofi-Aventis Deutschland Gmbh Clutch mechanism
EP2364740A1 (en) * 2010-03-09 2011-09-14 Sanofi-Aventis Deutschland GmbH Arrangement for transferring a translation of a drive means to a plunger
JP6173210B2 (ja) * 2010-08-19 2017-08-02 ノボ・ノルデイスク・エー／エス 針シールド、減衰機構、及び聴覚と触覚によるフィードバックを有する、針を手動で挿入するための医療用自動注射装置
EP2468337A1 (en) * 2010-12-21 2012-06-27 Sanofi-Aventis Deutschland GmbH Back-end device for an auto-injector and auto-injector
GB2487235A (en) 2011-01-17 2012-07-18 Owen Mumford Ltd Injection device with pneumatic damping of the drive mechanism
US9084849B2 (en) * 2011-01-26 2015-07-21 Kaleo, Inc. Medicament delivery devices for administration of a medicament within a prefilled syringe
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CN108888836B (zh) * 2012-10-17 2021-09-07 椭元医疗技术有限公司 自动药物输送装置
CN104884105B (zh) * 2013-01-10 2018-01-19 诺和诺德股份有限公司 具有剂量采集装置的医用注射系统
US20160106920A1 (en) 2013-06-03 2016-04-21 Novo Nordisk A/S Medical Injection Device
GB2549750A (en) * 2016-04-27 2017-11-01 Owen Mumford Ltd Medicament delivery device

Also Published As

Publication number Publication date
JP7413325B2 (ja) 2024-01-15
AU2016347644B2 (en) 2021-04-01
MX2022010594A (es) 2022-09-09
EP3162395A1 (en) 2017-05-03
ES2959440T3 (es) 2024-02-26
DK3368101T3 (da) 2019-11-11
CA3002301A1 (en) 2017-05-04
AU2021204659A1 (en) 2021-07-22
SI3368101T1 (sl) 2019-11-29
LT3368101T (lt) 2019-11-11
CY1122354T1 (el) 2021-01-27
US11033684B2 (en) 2021-06-15
EP4233938A2 (en) 2023-08-30
EP3583966B1 (en) 2023-07-26
AU2016347644A1 (en) 2018-04-26
JP2023075320A (ja) 2023-05-30
MX395072B (es) 2025-03-24
PL3368101T3 (pl) 2020-01-31
HUE045575T2 (hu) 2020-01-28
EP4233938A3 (en) 2024-02-28
AU2021204659B2 (en) 2023-02-09
AU2023202885A1 (en) 2023-05-25
MX2018005110A (es) 2018-06-06
US20210268192A1 (en) 2021-09-02
PT3368101T (pt) 2019-11-05
US20180304014A1 (en) 2018-10-25
JP2025103048A (ja) 2025-07-08
AU2025203511A1 (en) 2025-06-05
EP3583966A3 (en) 2020-03-11
ES2751074T3 (es) 2020-03-30
US12186536B2 (en) 2025-01-07
JP2018531702A (ja) 2018-11-01
EP3583966A2 (en) 2019-12-25
US20250082858A1 (en) 2025-03-13
EP3368101B1 (en) 2019-09-04
JP2021191437A (ja) 2021-12-16
WO2017072333A1 (en) 2017-05-04
AU2023202885B2 (en) 2025-02-27
EP3368101A1 (en) 2018-09-05

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